Hypertension:

Indications for: DIBENZYLINE

Treatment of pheochromocytoma, to control episodes of hypertension and sweating. May use concomitant β-blocker if tachycardia is excessive.

Adult Dosage:

Individualize. Initially 10mg twice daily. Increase dose every other day, usually to 20–40mg 2 or 3 times daily, until optimal dose obtained. Observe patients after each increase before instituting another increase.

Children Dosage:

Not recommended.

DIBENZYLINE Contraindications:

Conditions where a fall in BP may be undesirable.

DIBENZYLINE Warnings/Precautions:

Cerebral or coronary arteriosclerosis. Renal damage. May aggravate respiratory infections. Pregnancy (Cat.C). Nursing mothers: not recommended.

DIBENZYLINE Classification:

Alpha adrenergic blocker.

DIBENZYLINE Interactions:

Concomitant drugs that stimulate both alpha- and beta-adrenergic receptors (eg, epinephrine) may produce exaggerated hypotensive response and tachycardia. Blocks hyperthermia production by levarterenol. Blocks hypothermia production by reserpine.

Adverse Reactions:

Postural hypotension, tachycardia, inhibition of ejaculation, nasal congestion, miosis, GI upset, drowsiness, fatigue. May be carcinogenic (w. long-term use: not recommended).

How Supplied:

Caps—100