Colorectal disorders:
Indications for: CORTIFOAM
Adjunct in ulcerative proctitis in patients who cannot retain steroid enemas.
Adult Dosage:
1 applicatorful rectally (80mg hydrocortisone) 1–2 times daily for 2–3 weeks. Then every other day. Discontinue if no improvement within 2–3 weeks.
Children Dosage:
Not recommended.
CORTIFOAM Contraindications:
Rectal obstruction. Abscess. Perforation. Peritonitis. Fresh intestinal anastomoses. Extensive fistulas and sinus tracts. Tuberculosis. Ocular herpes simplex. Psychosis. Peptic ulcer. Glomerulonephritis. Myasthenia gravis. Osteoporosis. Diverticulitis. Thrombophlebitis. Diabetes. Hyperthyroidism. Acute coronary disease. Hypertension. Limited cardiac reserve. Infections.
CORTIFOAM Warnings/Precautions:
Postileorectostomy: not recommended. Exposure to varicella or vaccinia. Severe ulcerative disease. CHF. Renal or hepatic dysfunction. Monitor adrenal function and serum electrolytes. Avoid abrupt cessation. Vaccinations. Pregnancy (Cat.C). Nursing mothers.
CORTIFOAM Classification:
Steroid.
CORTIFOAM Interactions:
May antagonize insulin or oral hypoglycemics, anticoagulants, aspirin. Hypokalemia with amphotericin B or diuretics. May be potentiated by macrolides, cyclosporine.
Adverse Reactions:
Hypertension, fluid retention, hypokalemia, adrenal suppression, cataracts, glaucoma, psychosis, dysmenorrhea, myopathy, neuropathy, thrombophlebitis, peptic ulcer, impaired wound healing, convulsions, local irritation (folliculitis, hypertrichosis, acne, hypopigmentation, macerations, dermal and epidermal atrophy, secondary infections, striae, miliaria).
How Supplied:
Aerosol—15g (w. applicator)
