Narcotic analgesics:

Indications for: Butorphanol Nasal Spray

Pain management when opioid analgesia is appropriate.

Adult Dosage:

≥18 years: initially 1 spray in 1 nostril, repeat after 60–90 minutes if needed (Elderly: 90–120 minutes); may repeat in 3–4 hours. Or, may give 1 spray in each nostril, may repeat after 3–4 hours.

Children Dosage:

<18 years: not recommended.

Butorphanol Nasal Spray Warnings/Precautions:

Head injury. Increased intracranial pressure. Biliary tract surgery. Respiratory, cardiac, renal, or hepatic dysfunction. MI. Ventricular dysfunction. Coronary insufficiency. Hypertension. May precipitate withdrawal in narcotic addicts. Elderly. Labor & delivery. Pregnancy (Cat.C). Nursing mothers.

Butorphanol Nasal Spray Classification:

Opioid (agonist-antagonist).

Butorphanol Nasal Spray Interactions:

Potentiates CNS depression with alcohol, other CNS depressants. Nasal vasoconstrictors delay onset. May be antagonized by concomitant (within 30 minutes) sumatriptan nasal spray.

Adverse Reactions:

Sedation, dizziness, nasal congestion, insomnia, GI upset, respiratory depression, sweating, hypo- or hypertension, rash, vasodilation, palpitation, tinnitus, respiratory and CNS effects.


Formerly known under the brand name Stadol NS.

How Supplied:

Nasal Spray 2.5mL (8–15 sprays)—Contact supplier.