Miscellaneous ocular agents:

Indications for: BEOVU

Neovascular (wet) age-related macular degeneration (AMD). Diabetic macular edema (DME).

Adult Dosage:

Give by intravitreal inj. AMD: 6mg (0.05mL) once monthly (approx. 25–31 days) for the 1st 3 doses, followed by 6mg (0.05mL) once every 8–12 weeks. DME: 6mg (0.05mL) every 6 weeks (approx. 39–45 days) for the 1st 5 doses, followed by 6mg (0.05mL) once every 8–12 weeks.

Children Dosage:

Not established.

BEOVU Contraindications:

Ocular or periocular infections. Active intraocular inflammation.

BEOVU Warnings/Precautions:

Must only be administered by a qualified physician. Monitor for endophthalmitis, retinal detachments, retinal vasculitis and/or retinal vascular occlusion, elevation in IOP, and perfusion of optic nerve head following inj. Potential risk of arterial thromboembolic events (eg, nonfatal stroke or MI, vascular death). Advise females of reproductive potential to use effective contraception during and for ≥1 month after the last dose. Pregnancy. Nursing mothers: not recommended (during and for ≥1 month after the last dose).

BEOVU Classification:

Vascular endothelial growth factor (VEGF) inhibitor.

Adverse Reactions:

Vision blurred, cataract, conjunctival hemorrhage, eye pain, vitreous floaters; hypersensitivity reactions.

Generic Drug Availability:


How Supplied:

Single-dose vial (w. needle), single-dose prefilled syringe—1