Anemias:
Indications for: AURYXIA
Iron deficiency anemia in adults with chronic kidney disease not on dialysis.
Adult Dosage:
Swallow whole. Take with meals. Initially 1 tab three times daily; titrate as needed to achieve hemoglobin target levels; max 12 tabs/day.
Children Dosage:
Not established.
AURYXIA Contraindications:
Iron overload syndromes (eg, hemochromatosis).
AURYXIA Warnings/Precautions:
Monitor serum phosphorus. Assess iron parameters (eg, serum ferritin, TSAT) prior to initiation and monitor during therapy. Accidental iron overdose (esp. in children <6yrs); may be fatal. Pregnancy. Nursing mothers.
AURYXIA Classification:
Hematinic.
AURYXIA Interactions:
Concomitant IV iron; may require dose reduction or discontinuation of IV therapy. Give doxycycline at least 1hr before Auryxia. Give ciprofloxacin at least 2hrs before or after Auryxia. Concomitant drugs with narrow therapeutic range; consider monitoring.
Adverse Reactions:
Diarrhea, discolored feces, constipation, nausea, vomiting, cough, abdominal pain, hyperkalemia; iron overload.
Generic Drug Availability:
NO
How Supplied:
Tabs—200
Hyperphosphatemia:
Indications for: AURYXIA
To control serum phosphorus levels in patients with chronic kidney disease on dialysis.
Adult Dosage:
Swallow whole. Take with meals. Initially 2 tabs three times daily; titrate in decrements or increments of 1–2 tabs daily as needed at 1-week or longer intervals to maintain target levels; max 12 tabs/day.
Children Dosage:
Not established.
AURYXIA Contraindications:
Iron overload syndromes (eg, hemochromatosis).
AURYXIA Warnings/Precautions:
Monitor serum phosphorus. Assess iron parameters (eg, serum ferritin, TSAT) prior to initiation and monitor during therapy. Accidental iron overdose (esp. in children <6yrs); may be fatal. Pregnancy. Nursing mothers.
AURYXIA Classification:
Phosphate binder.
AURYXIA Interactions:
Concomitant IV iron; may require dose reduction or discontinuation of IV therapy. Give doxycycline at least 1hr before Auryxia. Give ciprofloxacin at least 2hrs before or after Auryxia. Concomitant drugs with narrow therapeutic range; consider monitoring.
Adverse Reactions:
Diarrhea, discolored feces, constipation, nausea, vomiting, cough, abdominal pain, hyperkalemia; iron overload.
Generic Drug Availability:
NO
How Supplied:
Tabs—200
