Thromboembolic disorders:
Indications for: Aspirin/Dipyridamole
To reduce the risk of stroke in patients who have had transient ischemia of the brain or completed ischemic stroke due to thrombosis.
Adult Dosage:
Swallow whole. 1 cap twice daily, one in the morning and one in the evening. Alternative regimen in case of intolerable headaches: switch to 1 cap at bedtime and low-dose aspirin in AM; return to usual regimen as soon as possible, usually within 1 week.
Children Dosage:
Not recommended.
Aspirin/Dipyridamole Contraindications:
NSAID allergy. Patients with the syndrome of asthma, rhinitis, and nasal polyps. Viral infection in children/teens (risk of Reye syndrome).
Aspirin/Dipyridamole Warnings/Precautions:
Not interchangeable with individual components of aspirin and dipyridamole. Increased risk of bleeding, including GI bleed. History of active peptic ulcer, severe hepatic or renal dysfunction; avoid. Coronary artery disease. Pre-existing hypotension. Chronic, heavy alcohol use. Labor & delivery. Pregnancy. Nursing mothers.
Aspirin/Dipyridamole Classification:
Combination antiplatelet.
Aspirin/Dipyridamole Interactions:
Increased risk of bleeding with anticoagulants, antiplatelets, heparin, anagrelide, fibrinolytic therapy, alcohol, chronic NSAID use. Potentiates adenosine, acetazolamide, methotrexate, oral hypoglycemics. May antagonize ACE inhibitors, β-blockers, diuretics, cholinesterase inhibitors, uricosurics. May increase risk of renal dysfunction with NSAIDs. Monitor phenytoin, valproic acid, other anticonvulsants.
Adverse Reactions:
Headache, dyspepsia, abdominal pain, nausea, diarrhea; bleeding risk, increased liver enzymes, hepatic failure.
Note:
Formerly known under the brand name Aggrenox.
How Supplied:
Contact supplier
