Indications for: APTENSIO XR

Attention deficit hyperactivity disorder.

Limitations of Use:

Pediatrics <6yrs: experienced higher rates of adverse reactions (esp. weight loss).

Adults and Children:

Individualize. Swallow whole or may open capsule and sprinkle contents onto applesauce. <6yrs: not established. ≥6yrs: 10mg once daily in the AM. May titrate dose in weekly increments of 10mg/day. Max 60mg/day. Discontinue if no improvement after dose adjustment over a 1-month period.

APTENSIO XR Contraindications:

During or within 14 days of MAOIs.

Boxed Warning:

Abuse and dependence.

APTENSIO XR Warnings/Precautions:

High potential for abuse and dependence; monitor. Increased risk of sudden death, stroke, and MI; assess for presence of cardiac disease before initiating. Avoid in known structural cardiac abnormalities, cardiomyopathy, serious arrhythmias, coronary artery disease, and other cardiac problems. Pre-existing psychotic disorder. Bipolar disorder. Screen for risk factors of developing a manic episode prior to initiation. Consider discontinuing if new psychotic/manic symptoms occur. Peripheral vasculopathy including Raynaud's phenomenon; monitor for digital changes. Monitor growth (in children), BP, HR. Reduce dose or discontinue if paradoxical aggravation of symptoms occurs. Write ℞ for smallest practical amount. Reevaluate periodically. Pregnancy. Nursing mothers: monitor infants.

APTENSIO XR Classification:

CNS stimulant.

APTENSIO XR Interactions:

See Contraindications. Hypertensive crisis with concomitant MAOIs. Risk of serotonin syndrome with serotonergic drugs.

Adverse Reactions:

Headache, insomnia, abdominal pain, decreased appetite, nausea, vomiting, dizziness; hypertension, tachycardia, priapism.

How Supplied:

Ext-rel caps—90