Muscle spasms:
Indications for AMRIX:
Adjunct to rest and physical therapy for relief of muscle spasm associated with acute, painful musculoskeletal conditions.
Adult Dosage:
Swallow whole; or may sprinkle contents on applesauce and swallow immediately without chewing. Take at same time each day. 15mg once daily; may increase to 30mg/day given once daily. Max 2–3 weeks.
Children Dosage:
Not established.
AMRIX Contraindications:
Acute post-MI. Arrhythmias, heart block, other conduction disturbances. CHF. Hyperthyroidism. During or within 14 days of MAOIs.
AMRIX Warnings/Precautions:
Not effective in treating spasticity associated with cerebral or spinal chord disease or in children with cerebral palsy. Consider discontinuing if significant CNS symptoms develop. Urinary retention. Angle-closure glaucoma. Increased intraocular pressure. Hepatic impairment or elderly: not recommended. Pregnancy. Nursing mothers.
AMRIX Classification:
Muscle relaxant (central).
AMRIX Interactions:
See Contraindications. Hypertensive crisis with MAOIs. Increased risk of serotonin syndrome with other serotonergic drugs (eg, SSRIs, SNRIs, tricyclic antidepressants, tramadol, bupropion, meperidine, verapamil, MAOIs); discontinue if occurs. May potentiate alcohol, barbiturates, other CNS depressants. Caution with anticholinergics. May antagonize guanethidine and similar acting compounds. May enhance seizure risk with concomitant tramadol.
Adverse Reactions:
Dry mouth, dizziness, fatigue, constipation, nausea, dyspepsia, somnolence; serotonin syndrome, cardiovascular effects.
How Supplied:
Caps—60
