Migraine and headache:
Indications for AJOVY:
Prophylaxis of migraine.
Give by SC inj into abdomen, thigh, or upper arm. 225mg monthly or 675mg (given as 3 consecutive 225mg inj) every 3 months.
Consider discontinuing if hypersensitivity reaction occurs. Pregnancy. Nursing mothers.
Calcitonin gene-related peptide (CGRP) receptor antagonist.
Inj site reactions (eg, pain, induration, erythema); hypersensitivity reactions.
Half-life: ~31 days.
Generic Drug Availability:
Single-dose prefilled syringe—1; Single-dose prefilled autoinjector—1, 3