CKD

Acute Renal Failure in CKD Patients Less Likely With PCI

Acute Renal Failure in CKD Patients Less Likely With PCI

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In a study, percutaneous coronary intervention was associated with a 72% decreased risk of acute renal failure compared with coronary artery bypass grafting in patients with chronic kidney disease.

Vitamin D Stores Lower in the Obese, Overweight

Vitamin D Stores Lower in the Obese, Overweight

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Obese or overweight individuals have significantly lower levels of 25-hydroxyvitamin D than normal-weight individuals at any level of kidney function, a study found.

Correcting Metabolic Acidosis May Preserve Muscle Mass

Correcting Metabolic Acidosis May Preserve Muscle Mass

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Oral sodium bicarbonate treatment was associated with improved lean body mass and kidney function in patients with metabolic acidosis due to CKD stages 3 and 4.

Single-Dose Potassium-Lowering Drug Effective in CKD, ESRD

Single-Dose Potassium-Lowering Drug Effective in CKD, ESRD

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A single 30-gram oral dose of sodium polystyrene sulfonate resulted in a significant decrease in serum potassium within 24 hours.

CKD Prevalence, Progression Rate High Among Elderly Diabetics

CKD Prevalence, Progression Rate High Among Elderly Diabetics

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In a South Korean study, nearly 60% of elderly patients with type 2 diabetes had chronic kidney disease at baseline.

FGF23 Predicts Development of CKD Anemia

FGF23 Predicts Development of CKD Anemia

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Anemia is 66% and 84% more likely to develop among patients in the 3rd and 4th quartiles of serum fibroblast growth factor 23 level vs those in the 1st quartile.

Studies Provide Detailed Look at Treatment-Related Hyperkalemia

Studies Provide Detailed Look at Treatment-Related Hyperkalemia

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Rates of hyperkalemia associated with receipt of renin-angiotensin-aldosterone system inhibitors vary by age and comorbidities.

Hyperkalemia Common in Stages 2-5 CKD

Hyperkalemia Common in Stages 2-5 CKD

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Longitudinal study with preplanned serum potassium measurements may provide a more accurate estimate of the burden of hyperkalemia among CKD patients.

Tolvaptan Cleared in US for ADPKD in Adults

Tolvaptan Cleared in US for ADPKD in Adults

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Originally approved for hyponatremia, the medication is the first FDA-approved treatment for rapidly progressing autosomal dominant polycystic kidney disease in adults.

Post-Parathyroidectomy Predictors of Hungry Bone Syndrome Identified

Post-Parathyroidectomy Predictors of Hungry Bone Syndrome Identified

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Predictors of hungry bone syndrome after parathyroidectomy include lower pre- and post-op calcium levels, according to a new study.

No Reduction in Platelets Found With IV Iron Use in CKD

No Reduction in Platelets Found With IV Iron Use in CKD

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New study shows that IV iron repletion with sodium ferric gluconate complex increased platelet count significantly at week 3 post-infusion and non-significantly at week 4.

Fenofibrate Therapy Slows CKD Progression in Diabetics

Fenofibrate Therapy Slows CKD Progression in Diabetics

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In a study of patients with type 2 diabetes, researchers observed a significantly lower annual decline in estimated glomerular filtration rate among those treated with fenofibrates vs placebo.

ADPKD Linked to Lower Mortality in Peritoneal Dialysis Patients

ADPKD Linked to Lower Mortality in Peritoneal Dialysis Patients

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Among patients on peritoneal dialysis, the odds of death are 32% lower among those with vs without autosomal dominant polycystic kidney disease, meta-analysis finds.

High Mean Corpuscular Volume Ups Hemodialysis Patient Death Risk

High Mean Corpuscular Volume Ups Hemodialysis Patient Death Risk

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Study of 109,501 incidental HD patients reveals an association between high mean corpuscular volume and increased risk of all-cause, cardiovascular, and infection-related mortality.

Extended-Release Calcifediol Reduces Bone Turnover in SHPT

Extended-Release Calcifediol Reduces Bone Turnover in SHPT

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Levels of the bone turnover markers CTX and P1NP declined over approximately 6 months of treatment patients with CKD and secondary hyperparathyroidism.

ADPKD-Related Kidney Failure Occurs Earlier in Non-Hispanic Blacks

ADPKD-Related Kidney Failure Occurs Earlier in Non-Hispanic Blacks

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Among patients younger than 40, the prevalence of end-stage renal disease secondary to ADPKD was 9.94% among non-Hispanic blacks vs 7.68% among non-Hispanic whites.

Outpatient AKI Is a Risk Factor for Death, Adverse Renal Outcomes

Outpatient AKI Is a Risk Factor for Death, Adverse Renal Outcomes

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In the most comprehensive study of its kind, investigators find that acute kidney injury not requiring hospitalization is associated with a 90% increased mortality risk.

Renal Replacement Therapy Trends in ADPKD Characterized

Renal Replacement Therapy Trends in ADPKD Characterized

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Patients with end-stage renal disease (ESRD) due to autosomal polycystic kidney disease are more likely to receive a kidney transplant than those with ESRD from other causes, new study finds.

GFR Decline Tied to Protein Intake in Diabetic Blacks

GFR Decline Tied to Protein Intake in Diabetic Blacks

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The percentage decline in estimated glomerular filtration rate over an 8-year period was greater among those with vs without diabetes across all quintiles of protein intake.

Pulmonary Hypertension Linked With Worse Prognosis in CKD, ESRD

Pulmonary Hypertension Linked With Worse Prognosis in CKD, ESRD

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Pulmonary hypertension in patients with any degree of renal insufficiency is associated with elevated risks of cardiovascular events and death.

Childhood Kidney Disease Ups Risk for Kidney Failure Later in Life

Childhood Kidney Disease Ups Risk for Kidney Failure Later in Life

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In an Israeli study, individuals who had any type of kidney disease as children had a 4-fold increased risk of end-stage renal disease in adulthood.

Kidney Disease Risk May Be Reduced With Bariatric Surgery

Kidney Disease Risk May Be Reduced With Bariatric Surgery

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At 1 and 7 years after bariatric surgery, 63% and 53% of patients at moderate risk for chronic kidney disease before surgery had an improvement in their CKD risk category.

Early RRT for Acute Kidney Injury Not Superior

Early RRT for Acute Kidney Injury Not Superior

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Early and late initiation of renal replacement therapy for AKI in critically ill patients are associated with similar long-term risks of death, chronic kidney disease, and end-stage renal disease.

Total Kidney Volume in ADPKD Predicts CKD Progression

Total Kidney Volume in ADPKD Predicts CKD Progression

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Each 100 mL/m increment in baseline height-adjusted total kidney volume is associated with 38% and 42% greater odds of developing stage 3 and 4 chronic kidney disease, respectively.

Some High-risk Heart Failure Patients Benefit From MRAs

Some High-risk Heart Failure Patients Benefit From MRAs

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Mineralocorticoid receptor antagonists found to lower hospital readmission risk in patients with heart failure and concomitant diabetes or renal insufficiency.

Whole-exome Sequencing Aids Diagnosis of CKD of Unknown Cause

Whole-exome Sequencing Aids Diagnosis of CKD of Unknown Cause

A fourth of adults with CKD of unknown cause, familial nephropathy, or hypertension have diagnosed mutations that can be identified using WES.

Diabetic CKD Patients Survive Longer With Metformin

Diabetic CKD Patients Survive Longer With Metformin

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Diabetic patients with chronic kidney disease starting treatment with metformin have a 36% decreased risk of death compared with those starting on a sulfonylurea, study finds.

Intensive Blood Pressure Control May Not Benefit CKD Patients

Intensive Blood Pressure Control May Not Benefit CKD Patients

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Post hoc analysis of SPRINT finds no significant difference in the incidence of fatal and nonfatal cardiovascular events among patients with moderate-to-advanced chronic kidney disease.

Drug Combo Promising for HCV Infection in Patients With Advanced CKD

Drug Combo Promising for HCV Infection in Patients With Advanced CKD

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Researchers report a high rate of sustained virologic response after 12 weeks of treatment with a ribavirin-free co-formulation of glecaprevir and pibrentasvir.

Pruritus in Hemodialysis Patients Underestimated, Undertreated

Pruritus in Hemodialysis Patients Underestimated, Undertreated

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Among hemodialysis patients always or nearly always bothered by itchy skin, 17% did not report their symptoms to a health care provider and 18% used no treatment for the condition.

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