Chronic Kidney Disease

Acute Renal Failure in CKD Patients Less Likely With PCI

Acute Renal Failure in CKD Patients Less Likely With PCI

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In a study, percutaneous coronary intervention was associated with a 72% decreased risk of acute renal failure compared with coronary artery bypass grafting in patients with chronic kidney disease.

Vitamin D Stores Lower in the Obese, Overweight

Vitamin D Stores Lower in the Obese, Overweight

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Obese or overweight individuals have significantly lower levels of 25-hydroxyvitamin D than normal-weight individuals at any level of kidney function, a study found.

Correcting Metabolic Acidosis May Preserve Muscle Mass

Correcting Metabolic Acidosis May Preserve Muscle Mass

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Oral sodium bicarbonate treatment was associated with improved lean body mass and kidney function in patients with metabolic acidosis due to CKD stages 3 and 4.

Single-Dose Potassium-Lowering Drug Effective in CKD, ESRD

Single-Dose Potassium-Lowering Drug Effective in CKD, ESRD

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A single 30-gram oral dose of sodium polystyrene sulfonate resulted in a significant decrease in serum potassium within 24 hours.

Stroke, Death Risk Increase With CKD and AFib

Stroke, Death Risk Increase With CKD and AFib

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Atrial fibrillation may up stroke risk as much as 1.5 to 2 times in CKD patients, according to study findings.

DOACs Increase Bleeding Risk More Than Warfarin in CKD

DOACs Increase Bleeding Risk More Than Warfarin in CKD

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DOAC users with eGFRs less than 60 mL/min/1.73m2 had a 23% higher risk for bleeding than warfarin users.

New Technique Allows Rapid Bedside Measurement of GFR

New Technique Allows Rapid Bedside Measurement of GFR

VFI approach for direct measurement of glomerular filtration rate is accurate and reproducible.

Rates of Cardiac Stress Testing Down but Still Higher in CKD

Rates of Cardiac Stress Testing Down but Still Higher in CKD

Decline in rates of cardiac stress testing in Medicare beneficiaries aged 66 years from 2008 to 2012.

CKD Patients Often Excluded From Cancer Trials

CKD Patients Often Excluded From Cancer Trials

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Even patients with mild chronic kidney disease were prevented from participating in clinical trials of drugs for bladder, breast, colorectal, lung, and prostate cancers.

Daily Coffee Drinking May Prevent CKD

Daily Coffee Drinking May Prevent CKD

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Drinking one cup of coffee daily was associated with 24% lower risk for chronic kidney disease.

CKD Prevalence, Progression Rate High Among Elderly Diabetics

CKD Prevalence, Progression Rate High Among Elderly Diabetics

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In a South Korean study, nearly 60% of elderly patients with type 2 diabetes had chronic kidney disease at baseline.

Low-Level Lead Exposure Found to Increase CKD Risk

Low-Level Lead Exposure Found to Increase CKD Risk

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Individuals with higher blood lead levels experienced greater decreases in eGFR.

Substance Use Ups Risks for CKD Progression, Mortality

Substance Use Ups Risks for CKD Progression, Mortality

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Persistent cocaine use by patients with chronic kidney disease more than doubled their risk for death.

FGF23 Predicts Development of CKD Anemia

FGF23 Predicts Development of CKD Anemia

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Anemia is 66% and 84% more likely to develop among patients in the 3rd and 4th quartiles of serum fibroblast growth factor 23 level vs those in the 1st quartile.

Studies Provide Detailed Look at Treatment-Related Hyperkalemia

Studies Provide Detailed Look at Treatment-Related Hyperkalemia

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Rates of hyperkalemia associated with receipt of renin-angiotensin-aldosterone system inhibitors vary by age and comorbidities.

Preeclampsia Increases Kidney Disease Risk Post-Pregnancy

Preeclampsia Increases Kidney Disease Risk Post-Pregnancy

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The risk of chronic kidney disease among women who experience preeclampsia is particularly elevated within 5 years of delivery.

Hyperkalemia Common in Stages 2-5 CKD

Hyperkalemia Common in Stages 2-5 CKD

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Longitudinal study with preplanned serum potassium measurements may provide a more accurate estimate of the burden of hyperkalemia among CKD patients.

Bardoxolone Shows Promise for ADPKD

Bardoxolone Shows Promise for ADPKD

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In a phase 2 trial that enrolled 31 patients with autosomal dominant polycystic kidney disease, treatment with bardoxolone resulted in a significant increase in kidney function.

Midstream Urine Microbiome Diverse in Seniors With CKD

Midstream Urine Microbiome Diverse in Seniors With CKD

After adjustment for demographics and diabetes status, microbiome diversity linked to estimated GFR.

Increasing Water Intake Does Not Slow eGFR Decline in CKD

Increasing Water Intake Does Not Slow eGFR Decline in CKD

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A nonsignificant 0.3 mL/min/1.73 m2 difference in eGFR was found between the usual and increased water intake groups after 1 year.

Coaching to improve water intake does not improve kidney function in adults with chronic kidney disease

1. In this randomized controlled trial, coaching to improve daily fluid intake did not improve kidney function in patients with Chronic Kidney Disease. 2. Increasing fluid intake via coaching was adequate to lower vasopressin secretion in patients. Evidence Rating Level: 1 (Excellent) Study Rundown: In both preclinical animal models and clinical human studies, increased water []

Cystatin C Tied to Cumulative Hearing Impairment

Cystatin C Tied to Cumulative Hearing Impairment

Cystatin C as biomarker, kidney function marker linked to 20-year cumulative incidence of HI.

Sleep Duration Tied With Quality of Life in CKD

Sleep Duration Tied With Quality of Life in CKD

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Patients with chronic kidney disease who sleep 7 hours a night have the highest health-related quality of life, new study finds.

Tolvaptan Cleared in US for ADPKD in Adults

Tolvaptan Cleared in US for ADPKD in Adults

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Originally approved for hyponatremia, the medication is the first FDA-approved treatment for rapidly progressing autosomal dominant polycystic kidney disease in adults.

Post-Parathyroidectomy Predictors of Hungry Bone Syndrome Identified

Post-Parathyroidectomy Predictors of Hungry Bone Syndrome Identified

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Predictors of hungry bone syndrome after parathyroidectomy include lower pre- and post-op calcium levels, according to a new study.

No Reduction in Platelets Found With IV Iron Use in CKD

No Reduction in Platelets Found With IV Iron Use in CKD

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New study shows that IV iron repletion with sodium ferric gluconate complex increased platelet count significantly at week 3 post-infusion and non-significantly at week 4.

Fenofibrate Therapy Slows CKD Progression in Diabetics

Fenofibrate Therapy Slows CKD Progression in Diabetics

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In a study of patients with type 2 diabetes, researchers observed a significantly lower annual decline in estimated glomerular filtration rate among those treated with fenofibrates vs placebo.

ADPKD Linked to Lower Mortality in Peritoneal Dialysis Patients

ADPKD Linked to Lower Mortality in Peritoneal Dialysis Patients

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Among patients on peritoneal dialysis, the odds of death are 32% lower among those with vs without autosomal dominant polycystic kidney disease, meta-analysis finds.

High Mean Corpuscular Volume Ups Hemodialysis Patient Death Risk

High Mean Corpuscular Volume Ups Hemodialysis Patient Death Risk

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Study of 109,501 incidental HD patients reveals an association between high mean corpuscular volume and increased risk of all-cause, cardiovascular, and infection-related mortality.

Extended-Release Calcifediol Reduces Bone Turnover in SHPT

Extended-Release Calcifediol Reduces Bone Turnover in SHPT

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Levels of the bone turnover markers CTX and P1NP declined over approximately 6 months of treatment patients with CKD and secondary hyperparathyroidism.

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