Chronic Kidney Disease

Statins Underused by Adults With Chronic Kidney Disease

Statins Underused by Adults With Chronic Kidney Disease

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Although a 2013 guideline recommended statin use to more than 65% of adults with CKD, only about 36% of adults with CKD were taking a statin in 2011-2014.

Personalized Tx May Extend Life in CKD With Small Renal Tumors

Personalized Tx May Extend Life in CKD With Small Renal Tumors

Routine partial nephrectomy yielded longest life expectancy in patients with normal renal function.

Novel Albuminuria Endpoints May Improve CKD Progression Trials

Novel Albuminuria Endpoints May Improve CKD Progression Trials

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Two companion meta-analyses show that early changes in albuminuria can predict the risk for end-stage renal disease.

New Predictor of In-Hospital Acute Kidney Injury Identified

New Predictor of In-Hospital Acute Kidney Injury Identified

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Elevated calcium-phosphate product at hospital admission is associated with an increased risk of acute kidney injury.

Spironolactone Helps HF Patients With CKD, But Ups Hyperkalemia Risk

Spironolactone Helps HF Patients With CKD, But Ups Hyperkalemia Risk

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Spironolactone improved cardiovascular outcomes in heart failure patients with chronic kidney disease, but increased their risk of hyperkalemia.

Sugar-Sweetened Drinks Linked to Chronic Kidney Disease Risk

Sugar-Sweetened Drinks Linked to Chronic Kidney Disease Risk

Odds of CKD up with beverage pattern consisting of higher intake of sweetened soda, fruit drinks, water

Exome Sequencing Zeroes in on Genetic Diagnoses in CKD

Exome Sequencing Zeroes in on Genetic Diagnoses in CKD

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In a study of patients with chronic kidney disease, the technique for sequencing protein-coding genes yielded a genetic diagnosis in 9.3% of cases.

Chronic Kidney Disease Linked to Hepatitis B

Chronic Kidney Disease Linked to Hepatitis B

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In a study of nearly 300,000 South Koreans, individuals who tested positive for hepatitis B virus had an 11% higher risk of CKD.

Chronic Kidney Disease Progression Risk Lower in Women

Chronic Kidney Disease Progression Risk Lower in Women

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In a study of adults with mild-to-moderate chronic kidney disease, women had a significant 28% decreased risk of end-stage renal disease compared with men.

Multiple Comorbidities in CKD Patients Up Dialysis Initiation Risk

Multiple Comorbidities in CKD Patients Up Dialysis Initiation Risk

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Patients with stage 3-5 chronic kidney disease who have 3 or more comorbidities are 3 times more likely to start dialysis than those with no comorbidities, a study found.

Care for Chronic Kidney Disease Varies Across VA Facilities

Care for Chronic Kidney Disease Varies Across VA Facilities

Findings observed for veterans with diabetes and concomitant chronic kidney disease

Chronic Kidney Disease Burden Increasing in the US

Chronic Kidney Disease Burden Increasing in the US

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Study implicates growing prevalence of metabolic and dietary risk factors as important contributors to increases in CKD burden.

Home-Based Intervention Helpful for Disadvantaged CKD Patients

Home-Based Intervention Helpful for Disadvantaged CKD Patients

Rural Zuni Indians with kidney disease had improved activation in their own health and health care

Acute Kidney Injury Increases Risks for CKD, ESRD, and Mortality

Acute Kidney Injury Increases Risks for CKD, ESRD, and Mortality

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In a meta-analysis, the risks for premature death nearly doubled, CKD nearly tripled, and ESRD nearly quintupled after an episode of acute kidney injury.

ESA Use for Non-Dialysis CKD Anemia in Decline

ESA Use for Non-Dialysis CKD Anemia in Decline

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Use of erythropoiesis-stimulating agents to treat anemia in patients with non-dialysis-dependent chronic kidney disease has been decreasing since the October 2009 publication of TREAT results.

New Cholesterol Guidelines Consider CKD 'Risk-Enhancing'

New Cholesterol Guidelines Consider CKD 'Risk-Enhancing'

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In their 2018 cholesterol guidelines, the American Heart Association and American College of Cardiology recommend individualized risk and treatment options.

Allopurinol Linked to Reduced Risk for CKD Stage ≥3 in Gout

Allopurinol Linked to Reduced Risk for CKD Stage ≥3 in Gout

Allopurinol use is not associated with renal function decline among those with newly diagnosed gout.

Novel Acid-Binding Drug Effective for Metabolic Acidosis in CKD

Novel Acid-Binding Drug Effective for Metabolic Acidosis in CKD

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A polymer that binds to hydrochloric acid in the GI tract and does not enter the systemic circulation significantly improved serum bicarbonate levels compared with placebo.

High FGF23 Increases Fall Risk in CKD

High FGF23 Increases Fall Risk in CKD

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Highest vs lowest quartile of intact fibroblast growth factor 23 is associated with a 2-fold greater risk of a first fall in older patients.

High Uric Acid Raises Death Risk in CKD

High Uric Acid Raises Death Risk in CKD

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Patients with chronic kidney disease who have hyperuricemia have a 3-fold higher risk of all-cause mortality.

Marijuana Use by CKD Patients May Hasten Renal Function Decline

Marijuana Use by CKD Patients May Hasten Renal Function Decline

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Marijuana users with chronic kidney disease experienced a significantly greater annual decline in estimated glomerular filtration rate than non-users, study finds.

Intensive SBP Tx Cuts Kidney Damage Biomarkers in Incident CKD

Intensive SBP Tx Cuts Kidney Damage Biomarkers in Incident CKD

Incident CKD accompanied by decreases in kidney damage biomarkers in setting of intensive treatment.

Poor Experience With PCP Linked to Hospitalization in CKD

Poor Experience With PCP Linked to Hospitalization in CKD

Risk of hospitalization up for Hispanic patients with lower scores on Ambulatory Care Experiences Survey

Payment Reform Urged To Encourage Chronic Kidney Disease Care

Payment Reform Urged To Encourage Chronic Kidney Disease Care

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Authors of a recent editorial contend that federal reimbursement polices discourage delivery of the complex care needed by patients with chronic kidney disease who are not on dialysis.

Inflammatory Marker Tied to Decline in Kidney Function

Inflammatory Marker Tied to Decline in Kidney Function

Soluble tumor necrosis factor receptor-1 tied to decline in multiethnic cohort

PCI, CABG Both Acceptable for CKD Patients With LMCAD

PCI, CABG Both Acceptable for CKD Patients With LMCAD

Patients with, without chronic kidney disease have less acute renal failure with PCI.

Kidney Function Decline in General Population Linked to Low Calcium

Kidney Function Decline in General Population Linked to Low Calcium

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Association found in a Japanese study of individuals in the general population who did not have chronic kidney disease.

Enlarged Kidneys in Neonates With Congenital Heart Disease

Enlarged Kidneys in Neonates With Congenital Heart Disease

Kidneys of neonates with left heart obstruction consistently found to be larger than normal

Hepatitis C Infection May Hasten Chronic Kidney Disease Progression

Hepatitis C Infection May Hasten Chronic Kidney Disease Progression

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Patients with both CKD and hepatitis C virus infection are at nearly 2-fold higher risk of end-stage renal disease with those who have CKD only.

CKD Associated With Increased Inter-Arm BP Difference

CKD Associated With Increased Inter-Arm BP Difference

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Increased inter-arm difference in systolic blood pressure independently predicts development of chronic kidney disease in the general population, a new study suggests.

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