Chronic Kidney Disease (CKD) News Archive
In their 2018 cholesterol guidelines, the American Heart Association and American College of Cardiology recommend individualized risk and treatment options.
Allopurinol use is not associated with renal function decline among those with newly diagnosed gout.
A polymer that binds to hydrochloric acid in the GI tract and does not enter the systemic circulation significantly improved serum bicarbonate levels compared with placebo.
Highest vs lowest quartile of intact fibroblast growth factor 23 is associated with a 2-fold greater risk of a first fall in older patients.
Patients with chronic kidney disease who have hyperuricemia have a 3-fold higher risk of all-cause mortality.
Marijuana users with chronic kidney disease experienced a significantly greater annual decline in estimated glomerular filtration rate than non-users, study finds.
Incident CKD accompanied by decreases in kidney damage biomarkers in setting of intensive treatment.
Risk of hospitalization up for Hispanic patients with lower scores on Ambulatory Care Experiences Survey
Authors of a recent editorial contend that federal reimbursement polices discourage delivery of the complex care needed by patients with chronic kidney disease who are not on dialysis.
Soluble tumor necrosis factor receptor-1 tied to decline in multiethnic cohort
Patients with, without chronic kidney disease have less acute renal failure with PCI.
Association found in a Japanese study of individuals in the general population who did not have chronic kidney disease.
Kidneys of neonates with left heart obstruction consistently found to be larger than normal
Patients with both CKD and hepatitis C virus infection are at nearly 2-fold higher risk of end-stage renal disease with those who have CKD only.
Increased inter-arm difference in systolic blood pressure independently predicts development of chronic kidney disease in the general population, a new study suggests.
The increased risk of chronic kidney disease is more pronounced among women who undergo the procedure at age 45 years or younger.
Researchers report a significant 41% decreased mortality risk among patients with advanced CKD who used statins compared with those who did not.
Low eGFR and worsening renal function are independently associated with a nearly 3-fold increased mortality risk among patients undergoing percutaneous coronary intervention.
Researchers find that physicians prescribe much longer courses of PPI therapy to patients with vs without CKD, despite the potential nephrotoxic effects.
Among individuals with chronic kidney disease, those in the top quartile of daily caffeine consumption had a 25% lower risk of death vs those in the bottom quartile.
Japanese post-marketing study identified no new safety concerns among patients with non-dialysis chronic kidney disease treated with darbepoetin alfa and followed up for 3 years.
In a Spanish study, endoscopic evaluation of patients with CKD and anemia revealed that 68.2% of patients had at least 1 gastrointestinal lesion.
New study reveals a type 2 diabetes incidence rate of 17.81 cases per 1000 person-years, a rate much higher than in the general population.
Study of patients with CKD stage 3 and asymptomatic hyperuricemia showed that febuoxostat ameliorated the annual decline in eGFR vs placebo in those without proteinuria.
Low serum sodium chloride concentrations are associated with an increased risk of renal function decline events, especially among patients with CKD stage G4 and anemic patients.
Concerns about nutritional deficiency in CKD patients are unfounded, and plant-based diets may actually be good for them, the authors of a new report contend.
A new study found that 24-hour urine phosphorus is inversely related to whole-body retention, but is not related to net intestinal absorption.
In a study, percutaneous coronary intervention was associated with a 72% decreased risk of acute renal failure compared with coronary artery bypass grafting in patients with chronic kidney disease.
Obese or overweight individuals have significantly lower levels of 25-hydroxyvitamin D than normal-weight individuals at any level of kidney function, a study found.
Oral sodium bicarbonate treatment was associated with improved lean body mass and kidney function in patients with metabolic acidosis due to CKD stages 3 and 4.
A single 30-gram oral dose of sodium polystyrene sulfonate resulted in a significant decrease in serum potassium within 24 hours.
Atrial fibrillation may up stroke risk as much as 1.5 to 2 times in CKD patients, according to study findings.
DOAC users with eGFRs less than 60 mL/min/1.73m2 had a 23% higher risk for bleeding than warfarin users.
VFI approach for direct measurement of glomerular filtration rate is accurate and reproducible.
Decline in rates of cardiac stress testing in Medicare beneficiaries aged 66 years from 2008 to 2012.
Even patients with mild chronic kidney disease were prevented from participating in clinical trials of drugs for bladder, breast, colorectal, lung, and prostate cancers.
Drinking one cup of coffee daily was associated with 24% lower risk for chronic kidney disease.
Individuals with higher blood lead levels experienced greater decreases in eGFR.
In a South Korean study, nearly 60% of elderly patients with type 2 diabetes had chronic kidney disease at baseline.
Persistent cocaine use by patients with chronic kidney disease more than doubled their risk for death.
Anemia is 66% and 84% more likely to develop among patients in the 3rd and 4th quartiles of serum fibroblast growth factor 23 level vs those in the 1st quartile.
Rates of hyperkalemia associated with receipt of renin-angiotensin-aldosterone system inhibitors vary by age and comorbidities.
The risk of chronic kidney disease among women who experience preeclampsia is particularly elevated within 5 years of delivery.
Longitudinal study with preplanned serum potassium measurements may provide a more accurate estimate of the burden of hyperkalemia among CKD patients.
In a phase 2 trial that enrolled 31 patients with autosomal dominant polycystic kidney disease, treatment with bardoxolone resulted in a significant increase in kidney function.
After adjustment for demographics and diabetes status, microbiome diversity linked to estimated GFR.
A nonsignificant 0.3 mL/min/1.73 m2 difference in eGFR was found between the usual and increased water intake groups after 1 year.
Cystatin C as biomarker, kidney function marker linked to 20-year cumulative incidence of HI.
Patients with chronic kidney disease who sleep 7 hours a night have the highest health-related quality of life, new study finds.
Originally approved for hyponatremia, the medication is the first FDA-approved treatment for rapidly progressing autosomal dominant polycystic kidney disease in adults.
Predictors of hungry bone syndrome after parathyroidectomy include lower pre- and post-op calcium levels, according to a new study.
New study shows that IV iron repletion with sodium ferric gluconate complex increased platelet count significantly at week 3 post-infusion and non-significantly at week 4.
In a study of patients with type 2 diabetes, researchers observed a significantly lower annual decline in estimated glomerular filtration rate among those treated with fenofibrates vs placebo.
Among patients on peritoneal dialysis, the odds of death are 32% lower among those with vs without autosomal dominant polycystic kidney disease, meta-analysis finds.
Study of 109,501 incidental HD patients reveals an association between high mean corpuscular volume and increased risk of all-cause, cardiovascular, and infection-related mortality.
Levels of the bone turnover markers CTX and P1NP declined over approximately 6 months of treatment patients with CKD and secondary hyperparathyroidism.
Among patients younger than 40, the prevalence of end-stage renal disease secondary to ADPKD was 9.94% among non-Hispanic blacks vs 7.68% among non-Hispanic whites.
In the most comprehensive study of its kind, investigators find that acute kidney injury not requiring hospitalization is associated with a 90% increased mortality risk.
However, culturally sensitive education, engagement can up community screening
In a trial, oral calcitriol of 0.5 mcg daily did not reduce hepcidin levels in patients with stage 3 to 4 CKD.
Findings based on a small study tracking patients with chronic kidney disease in the last year of life
Researchers compared current and past marijuana use to never users.
Patients with end-stage renal disease (ESRD) due to autosomal polycystic kidney disease are more likely to receive a kidney transplant than those with ESRD from other causes, new study finds.
Vitamin D levels increased from 13.2 to 33.7 ng/mL in nondialysis CKD patients treated with 50,000 units of cholecalciferol weekly for 12 weeks.
In multivariable analyses, CKD stage G3b or higher was significantly associated with worse progression-free and cancer-specific survival.
The percentage decline in estimated glomerular filtration rate over an 8-year period was greater among those with vs without diabetes across all quintiles of protein intake.
One possible explanation is that increased plasma levels of uremic solutes resulting from kidney disease may impair synaptic development.
Elevated plasma levels of copeptin, a measure of vasopressin, are associated with an increased risk for chronic kidney disease and other kidney diseases.
Study questions the efficacy and safety of prescribing anticoagulants to older patients with atrial fibrillation and nondialysis chronic kidney disease.
Abnormal calcium-phosphate metabolism appears to be an important pathogenic factor in the development of vascular calcification in patients with chronic kidney disease.
Pulmonary hypertension in patients with any degree of renal insufficiency is associated with elevated risks of cardiovascular events and death.
End-stage renal disease was 3.4 times more likely to develop among patients with immunoglobulin A nephropathy compared with those who had minimal change disease, study finds.
Risk scores summarizing 8 diseases, markers tied to cancer risk in dose-response manner
Study finds no difference in all-cause mortality among patients with chronic kidney disease and heart failure who received implantable cardioverter defibrillators and those who did not.
In an Israeli study, individuals who had any type of kidney disease as children had a 4-fold increased risk of end-stage renal disease in adulthood.
At 1 and 7 years after bariatric surgery, 63% and 53% of patients at moderate risk for chronic kidney disease before surgery had an improvement in their CKD risk category.
Early and late initiation of renal replacement therapy for AKI in critically ill patients are associated with similar long-term risks of death, chronic kidney disease, and end-stage renal disease.
Each 100 mL/m increment in baseline height-adjusted total kidney volume is associated with 38% and 42% greater odds of developing stage 3 and 4 chronic kidney disease, respectively.
Mineralocorticoid receptor antagonists found to lower hospital readmission risk in patients with heart failure and concomitant diabetes or renal insufficiency.
Pretreating enteral nutrition formula with sodium polystyrene sulfonate lowers potassium levels in hyperkalemic children with chronic kidney disease, small study finds.
CKD occurrence was seen in 3.4% of HIV patients receiving the combination of medications.
Antiretroviral therapies have prolonged the survival of HIV patients, but the drugs can have adverse effects on the kidneys.
In patients with stage 5 chronic kidney disease, lupus anticoagulant and combined thrombophilia occur more frequently in those with versus without calciphylaxis, case-control study shows.
Urinary ceruloplamin has potential to be a chronic kidney disease biomarker for patients with sickle cell anemia.
A fourth of adults with CKD of unknown cause, familial nephropathy, or hypertension have diagnosed mutations that can be identified using WES.
Diabetic patients with chronic kidney disease starting treatment with metformin have a 36% decreased risk of death compared with those starting on a sulfonylurea, study finds.
In a study, taking a medication not on a nephrologists' list, not taking a specified medication, taking different doses, or following a different frequency topped the list.
In the subcohorts of patients with a diagnosis of bipolar disorder, continuing lithium was associated with decreased end-stage CKD, whereas continuing anticonvulsants was not.
The model was based on 6 variables readily obtained at hospital discharge.
Fibrillary glomerulonephritis glomeruli exhibit overexpression of DNAJB9 protein.
No improvement for patients with MDD and chronic kidney disease without dialysis dependence.
Risk for both chronic kidney disease, end-stage renal disease higher with proton pump inhibitor use.
Patients with autosomal dominant polycystic kidney disease treated with tolvaptan experienced a 35% decrease in the annual rate of decline in eGFR.
Post hoc analysis of SPRINT finds no significant difference in the incidence of fatal and nonfatal cardiovascular events among patients with moderate-to-advanced chronic kidney disease.
Transcatheter aortic valve replacement increases the risk of requiring renal replacement therapy and the risk of death among patients with stage 4 or 5 CKD.
Direct oral anticoagulants not linked to increased risk of major bleeding, death in venous thromboembolism
Researchers report a high rate of sustained virologic response after 12 weeks of treatment with a ribavirin-free co-formulation of glecaprevir and pibrentasvir.
Uromodulin may be a novel predictive serum biomarker.
In a study, partial nephrectomy was associated with a 66% lower risk for stage 4 or higher CKD versus radical nephrectomy.
Study finds link between particulate matter and renal function.
Renal and Urology News Articles
- Younger Men With High-Grade PCa Less Likely to Die After RP Than RT
- Roxadustat Effective in Chronic Kidney Disease Patients With Anemia
- Novel Albuminuria Endpoints May Improve CKD Progression Trials
- Molidustat Promising for Renal Anemia
- Global Demand for Bladder Cancer Treatment Threatens Supply in 2019
- Low Vitamin D Tied to Risk for Renal Hyperfiltration in Healthy Adults
- Novel Albuminuria Endpoints May Improve CKD Progression Trials
- Younger Men With High-Grade PCa Less Likely to Die After RP Than RT
- Overactive Bladder Linked to Prostate Cancer ADT
- Second-Line Antidiabetic Meds May Impact Cardiovascular Risk
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NEPHROLOGY & UROLOGY NEWS
- Acute Kidney Injury (AKI)
- Chronic Kidney Disease (CKD)
- Contrast Nephropathy
- Cardiovascular Disease (CVD)
- Diabetic Nephropathy
- End-stage Renal Disease (ESRD)
- Lupus Nephritis
- Peritoneal Dialysis
- Secondary Hyperparathyroidism (SHPT)