Cardiovascular Disease News Archive

Skin Autofluorescence Predicts T2DM, Heart Disease, Mortality

Skin Autofluorescence Predicts T2DM, Heart Disease, Mortality

Prediction independent of traditional risk factors such as MetS, glucose, HbA1c in general population

Younger Patients Account for Increasing Proportion of AMI

Younger Patients Account for Increasing Proportion of AMI

Increase especially great among women, who were less likely to receive guideline-based treatment.

Several Risk Factors More Strongly Linked to MI in Women

Several Risk Factors More Strongly Linked to MI in Women

Blood pressure, smoking, type 1 and 2 diabetes linked to higher hazard ratios for women than men

Certain SGLT2 Inhibitors, GLP-1 RAs for T2DM Also Cut CV Risk

Certain SGLT2 Inhibitors, GLP-1 RAs for T2DM Also Cut CV Risk

Report provides guidance on reducing CV risk in patients with T2DM and atherosclerotic CV disease

Lower Mortality Seen for Cardiac Care at Top-Ranked Hospitals

Lower Mortality Seen for Cardiac Care at Top-Ranked Hospitals

But readmission rates similar for top-ranked, nonranked hospitals for acute MI and CABG

Gout Tied With Worse Outcomes in Obstructive Coronary Artery Disease

Gout Tied With Worse Outcomes in Obstructive Coronary Artery Disease

A history of gout was associated with worse outcomes in patients with obstructive coronary artery disease.

Onset of Musculoskeletal Adverse Events Varies Between Statins

Onset of Musculoskeletal Adverse Events Varies Between Statins

Significantly faster onset with atorvastatin, rosuvastatin versus simvastatin during monotherapy.

AHA: Lasting Benefit for CABG in Diabetes, Multivessel Disease

AHA: Lasting Benefit for CABG in Diabetes, Multivessel Disease

Lower all-cause mortality in CABG group vs PCI-DES group after median follow-up of 7.5 years.

Sudden Cardiac Death Rates Up in Blacks vs Whites

Sudden Cardiac Death Rates Up in Blacks vs Whites

Risk still up after adjustment for sociodemographics, comorbidity, behavioral measures of health

AHA: Icosapent Ethyl Cuts CV Risk From Elevated Triglycerides

AHA: Icosapent Ethyl Cuts CV Risk From Elevated Triglycerides

Ischemic events reduced among patients with elevated triglycerides despite taking statins

AHA: Dapagliflozin Noninferior to Placebo for MACE in T2DM

AHA: Dapagliflozin Noninferior to Placebo for MACE in T2DM

Treatment resulted in lower HF hospitalization rate in patients with, without atherosclerosis.

New Cholesterol Guidelines Consider CKD 'Risk-Enhancing'

New Cholesterol Guidelines Consider CKD 'Risk-Enhancing'

In their 2018 cholesterol guidelines, the American Heart Association and American College of Cardiology recommend individualized risk and treatment options.

AHA: Limited Benefit for n-3 Fatty Acids in CVD, Cancer Prevention

AHA: Limited Benefit for n-3 Fatty Acids in CVD, Cancer Prevention

Second study shows no significant results for vitamin D supplementation vs placebo.

Age, Racial Disparities Seen in Hospitalization for Heart Failure

Age, Racial Disparities Seen in Hospitalization for Heart Failure

Whites with heart failure more likely to be hospitalized for higher-clinical-acuity visits.

Some Weather Conditions Linked to Myocardial Infarction Risk

Some Weather Conditions Linked to Myocardial Infarction Risk

Each one-standard deviation increase in air temperature tied to 2.8% reduction in MI risk

Canagliflozin Approved to Reduce Risk of Major Adverse Cardiovascular Events

Canagliflozin Approved to Reduce Risk of Major Adverse Cardiovascular Events

The effect of Invokana on CV risk was evaluated in the CANVAS (CANagliflozin cardioVascular Assessment Study) Program in >10,000 adults with T2D who had established CV disease or were at risk for CV disease with ≥2 risk factors.

Statins Reduce Mortality Risk in Dialysis-Requiring AKI

Statins Reduce Mortality Risk in Dialysis-Requiring AKI

Statin use vs non-use among patients hospitalized with dialysis-requiring acute kidney injury is associated with decreased risks of 1-year and in-hospital all-cause mortality, a study found.

Advanced CKD May Be a Risk Factor for Medial Arterial Calcification

Advanced CKD May Be a Risk Factor for Medial Arterial Calcification

In a study, progression of calcification did not increase until eGFR falls below 40 mL/min/1.73 m2.

Frequent Hemodialysis Improves Serum Phosphate, Left Ventricular Mass

Frequent Hemodialysis Improves Serum Phosphate, Left Ventricular Mass

Patients who received hemodialysis 6 times per week instead of 3 showed improvements in biomarkers of mineral metabolism and left ventricular remodeling.

Magnesium Levels May Predict Peripheral Artery Disease Risk

Magnesium Levels May Predict Peripheral Artery Disease Risk

Higher magnesium levels are associated with a lower risk of peripheral artery disease, but only among individuals without impaired renal function.

Cardiovascular Event Risk in Dialysis Patients Higher Among Women

Cardiovascular Event Risk in Dialysis Patients Higher Among Women

In the first year after starting dialysis, women have 16% increased odds of major adverse cardiovascular events compared with men.

CT Abdominal Aortic Calcification Score Predicts CV Event Risk

CT Abdominal Aortic Calcification Score Predicts CV Event Risk

In asymptomatic patients, AUC was higher for AAC than for Framingham Risk Score at all time points.

High Variability in Metabolic Measures May Up Mortality

High Variability in Metabolic Measures May Up Mortality

Even greater risk for mortality, CV events in presence of several high-variability metabolic parameters

Intensive BP Therapy in Diabetes May Lower Risk for CV Events

Intensive BP Therapy in Diabetes May Lower Risk for CV Events

Findings based on data reweighted to reflect the adult population with diabetes in the US.

Albiglutide Beats Placebo for Cardiovascular Events in T2DM

Albiglutide Beats Placebo for Cardiovascular Events in T2DM

Despite having been withdrawn, albiglutide is superior to placebo for reducing cardiovascular events

Heart Attack Risk After Stone Procedure Linked to Metabolic Syndrome

Heart Attack Risk After Stone Procedure Linked to Metabolic Syndrome

Myocardial infarction following the kidney stone procedure is twice as likely among patients with 3 to 4 components of metabolic syndrome vs no components.

PCI, CABG Both Acceptable for CKD Patients With LMCAD

PCI, CABG Both Acceptable for CKD Patients With LMCAD

Patients with, without chronic kidney disease have less acute renal failure with PCI.

Enlarged Kidneys in Neonates With Congenital Heart Disease

Enlarged Kidneys in Neonates With Congenital Heart Disease

Kidneys of neonates with left heart obstruction consistently found to be larger than normal

Low eGFR, Worsening Renal Function Predict Higher Post-PCI Death Risk

Low eGFR, Worsening Renal Function Predict Higher Post-PCI Death Risk

Low eGFR and worsening renal function are independently associated with a nearly 3-fold increased mortality risk among patients undergoing percutaneous coronary intervention.

Hemodialysis Patient Death Risk Increased With Low Salt Intake

Hemodialysis Patient Death Risk Increased With Low Salt Intake

Salt intake below 6 g/day is associated with increased odds of all-cause and cardiovascular in patients on hemodialysis, Japanese study shows.

Cardiovascular Event Rates Vary by Kidney Failure Cause

Cardiovascular Event Rates Vary by Kidney Failure Cause

Among US dialysis patients, cardiovascular event rates are highest in those with diabetic nephropathy and lowest among those with IgA nephropathy.

More Targeted Sodium Reduction Strategies Proposed

More Targeted Sodium Reduction Strategies Proposed

New study suggests sodium intake is associated with cardiovascular disease and stroke only when mean sodium intake exceeds 5 grams per day.

Acute Renal Failure in CKD Patients Less Likely With PCI

Acute Renal Failure in CKD Patients Less Likely With PCI

In a study, percutaneous coronary intervention was associated with a 72% decreased risk of acute renal failure compared with coronary artery bypass grafting in patients with chronic kidney disease.

Parathyroidectomy for Secondary Hyperparathyroidism Improves Outcomes

Parathyroidectomy for Secondary Hyperparathyroidism Improves Outcomes

Surgical procedure can correct calcium and phosphorus abnormalities and improve coronary artery calcification, study finds.

Gout Increases Atrial Fibrillation Risk in the Elderly

Gout Increases Atrial Fibrillation Risk in the Elderly

A study of Medicare patients found that atrial fibrillation was nearly twice as likely to develop in those with vs without gout.

DOACs Increase Bleeding Risk More Than Warfarin in CKD

DOACs Increase Bleeding Risk More Than Warfarin in CKD

DOAC users with eGFRs less than 60 mL/min/1.73m2 had a 23% higher risk for bleeding than warfarin users.

USPSTF: Evidence Lacking for Nontraditional CVD Risk Factors

USPSTF: Evidence Lacking for Nontraditional CVD Risk Factors

Insufficient evidence for adding to traditional CVD risk assessment in asymptomatic adults.

Marriage May Protect Against Cardiovascular Disease

Marriage May Protect Against Cardiovascular Disease

Association seen between marital status and risk, prognosis of coronary heart disease or stroke

Apixaban May Reduce Major Bleeding Risk in Dialysis Patients With AFib

Apixaban May Reduce Major Bleeding Risk in Dialysis Patients With AFib

Apixaban recipients had a 28% lower risk for major bleeding compared with patients treated with warfarin.

Half of CV Events Occur from 2 to 5 Years Post-TIA, -Stroke

Half of CV Events Occur from 2 to 5 Years Post-TIA, -Stroke

Composite outcome occurred in 12.9%; 50.1% of events in second to fifth years.

Risk of CV Events Down With Med Diet Plus Olive Oil, Nuts

Risk of CV Events Down With Med Diet Plus Olive Oil, Nuts

Lower incidence of major cardiovascular events with Mediterranean diet supplemented with oil, nuts.

USPSTF: No to ECG Screening to Prevent CVD in Low-Risk Adults

USPSTF: No to ECG Screening to Prevent CVD in Low-Risk Adults

And evidence insufficient to recommend ECG screen for asymptomatic adults at intermediate or high risk.

Some Evidence Mobile Health Interventions Can Lower CVD Risk

Some Evidence Mobile Health Interventions Can Lower CVD Risk

mHealth programs generally improve overall cardiovascular disease risk, at least in the short term.

Erectile Dysfunction Strongly Predicts Cardiovascular Events

Erectile Dysfunction Strongly Predicts Cardiovascular Events

Men with erectile dysfunction (ED) are almost twice as likely to experience a cardiovascular event as those without ED.

No Consistent Cardiovascular Benefit Seen for Supplements

No Consistent Cardiovascular Benefit Seen for Supplements

Generally moderate- or low-quality evidence for preventive benefits, no effect, or increased risk

At Low Temps, Air Pollution May Up Risk of Sudden Cardiac Death

At Low Temps, Air Pollution May Up Risk of Sudden Cardiac Death

Particulate matter less than 2.5 m in diameter linked to higher sudden cardiac death risk in women

High Incidence of Sudden and/or Arrhythmic Death in CHD

High Incidence of Sudden and/or Arrhythmic Death in CHD

SAD cause of considerable proportion of deaths in CHD patients without severe systolic dysfunction

Metabolically Healthy Obesity Not Without Risk of CVD

Metabolically Healthy Obesity Not Without Risk of CVD

Findings show MHO is transient, so not a reliable predictor of lower cardiovascular risk in the future

Aortic Stiffness, Concentric LV Remodeling Linked in T2DM

Aortic Stiffness, Concentric LV Remodeling Linked in T2DM

Aortic distensibility independently linked to concentric left ventricular remodeling

High FGF-23 Linked to Recurrent Cardiac Events After ACS

High FGF-23 Linked to Recurrent Cardiac Events After ACS

FGF-23 in top quartile independently linked to greater risk of CV death, heart failure hospitalization.

No Reduced CVD Risk for SBP 120 mm Hg in Type 2 Diabetes

No Reduced CVD Risk for SBP <120 mm Hg in Type 2 Diabetes

Increased risk of CVD for achieved systolic blood pressure of 120 versus 130 or 140 mm Hg

Predialysis Nephrology Care Associated With Lower AFib Risk

Predialysis Nephrology Care Associated With Lower AFib Risk

Older patients who had more frequent nephrology visits prior to initiating dialysis had a lower incidence of atrial fibrillation in the year after initiating dialysis compared with those who did not.

Exercise Best Defense for Those at Genetic Risk for CVD

Exercise Best Defense for Those at Genetic Risk for CVD

Benefit of exercise against cardiovascular disease notable even among those at high genetic risk

Lonely Individuals May Have Increased Risk for AMI, Stroke

Lonely Individuals May Have Increased Risk for AMI, Stroke

Social isolation linked to increased mortality among individuals with history of AMI or stroke

Lead Exposure May Increase Risk for Cardiovascular Disease Mortality

Lead Exposure May Increase Risk for Cardiovascular Disease Mortality

Environmental lead exposure tied to all-cause, cardiovascular disease, ischemic heart disease mortality.

Exercise, Not Weight Loss, Linked to Lower Death Risk in CHD

Exercise, Not Weight Loss, Linked to Lower Death Risk in CHD

But no mortality risk reduction associated with weight loss in individuals with coronary heart disease

Generic Clopidogrel on Par With Plavix in Acute Coronary Syndrome

Generic Clopidogrel on Par With Plavix in Acute Coronary Syndrome

Clopidogrel noninferior for patients older than 65 years after acute coronary syndrome hospitalization.

FGF23 Tied to Coronary Heart Disease

FGF23 Tied to Coronary Heart Disease

After adjustment for hormone therapy use in women, associations no longer differed by sex

Mortality Risks Higher With Febuxostat vs Allopurinol

Mortality Risks Higher With Febuxostat vs Allopurinol

All-cause and cardiovascular mortality risks were 22% and 34% higher among febuxostat-treated patients vs allopurinol recipients.

Urgency Urinary Incontinence Linked to Previous Stroke

Urgency Urinary Incontinence Linked to Previous Stroke

Individuals who had a stroke or transient ischemic attack at age 60 to 64 had a 2-fold higher risk of UUI at age 68 years, a British study found.

Women With Ischemia, Non-Obstructive CAD May Have Myocardial Scars

Women With Ischemia, Non-Obstructive CAD May Have Myocardial Scars

Cardiac MR accurately diagnoses; myocardial scars may affect 8% of women with non-obstructive CAD

Readmission Rates High for HD Patients After CVD Hospitalization

Readmission Rates High for HD Patients After CVD Hospitalization

In a study, the 30-day readmission rate for hemodialysis patients hospitalized for cardiovascular events was 34.2%.

Testosterone Replacement Therapy Does Not Raise CV Risks

Testosterone Replacement Therapy Does Not Raise CV Risks

A large study of middle-aged men found that testosterone replacement therapy is associated with a small but significant decrease in cardiovascular risk and an increased risk of obstructive sleep apnea.

Vitamin D Supplementation Improves Endothelial Dysfunction in CKD

Vitamin D Supplementation Improves Endothelial Dysfunction in CKD

Vitamin D levels increased from 13.2 to 33.7 ng/mL in nondialysis CKD patients treated with 50,000 units of cholecalciferol weekly for 12 weeks.

Clarithromycin May Damage Heart, FDA Warns

Clarithromycin May Damage Heart, FDA Warns

Agency advising doctors to consider prescribing other antibiotics to patients with coronary heart disease

Lipoproteins, Lipids Similarly Linked With MI, Ischemic Stroke

Lipoproteins, Lipids Similarly Linked With MI, Ischemic Stroke

No association with ICH; within HDL, cholesterol inversely and triglyceride positively linked to MI

Anticoagulants Tied With Stroke, Hemorrhage in CKD

Anticoagulants Tied With Stroke, Hemorrhage in CKD

Study questions the efficacy and safety of prescribing anticoagulants to older patients with atrial fibrillation and nondialysis chronic kidney disease.

Coronary Artery Calcification Risk Factors in CKD Identified

Coronary Artery Calcification Risk Factors in CKD Identified

Abnormal calcium-phosphate metabolism appears to be an important pathogenic factor in the development of vascular calcification in patients with chronic kidney disease.

Blood Pressure Drugs With Statins Tied to Reduced Stroke Risk

Blood Pressure Drugs With Statins Tied to Reduced Stroke Risk

44% drop in stroke for those with intermediate CVD risk receiving candesartan/HCTZ, rosuvastatin

CKD, Diabetes, CVD, and More Boost Risks for Cancer, Mortality

CKD, Diabetes, CVD, and More Boost Risks for Cancer, Mortality

Risk scores summarizing 8 diseases, markers tied to cancer risk in dose-response manner

Omega-3 Fatty Acid Supplements Do Not Reduce Heart Disease Risk

Omega-3 Fatty Acid Supplements Do Not Reduce Heart Disease Risk

No significant association with fatal, nonfatal coronary heart disease, major vascular events

CKD Patients With Heart Failure May Not Benefit From ICDs

CKD Patients With Heart Failure May Not Benefit From ICDs

Study finds no difference in all-cause mortality among patients with chronic kidney disease and heart failure who received implantable cardioverter defibrillators and those who did not.

Nontraditional Risk Factors Predict Atherosclerotic Events in HD

Nontraditional Risk Factors Predict Atherosclerotic Events in HD

In hemodialysis patients, only non-traditional risk factors such as C-reactive protein predicted non-fatal myocardial infarction and other atherosclerotic events, researchers report.

Deportation Fears Tied With CV Risk Factors

Deportation Fears Tied With CV Risk Factors

High levels of worry in Mexican-origin women studied tied to risk of higher BMI, obesity, blood pressure.

Ultra-low Contrast Volume May Protect Kidneys in Advanced CKD

Ultra-low Contrast Volume May Protect Kidneys in Advanced CKD

No patient had a 25% or greater rise in serum creatinine 48 hours after receiving a median 13 mL of contrast for diagnostic coronary angiography, with an additional 13 mL for percutaneous coronary intervention.

Flu, Some Upper Respiratory Infections Up Heart Attacks

Flu, Some Upper Respiratory Infections Up Heart Attacks

Increased incidence of acute myocardial infarction in first 7 days after positive respiratory viral diagnosis

Smoking Just 1 Cigarette Daily Increases Heart Disease, Stroke

Smoking Just 1 Cigarette Daily Increases Heart Disease, Stroke

Men who smoked just one cigarette/day had 46% of excess relative risk of smoking 20/day.

Marijuana's Cardiovascular Effects Still Unknown

Marijuana's Cardiovascular Effects Still Unknown

Prospective studies needed to examine long-term effects of chronic marijuana use on CV health.

USPSTF Questions Nontraditional CVD Risk Factors for Assessment

USPSTF Questions Nontraditional CVD Risk Factors for Assessment

Second Grade I statement questions use of ABI for screening for peripheral artery disease, CVD risk.

High-grade Prostate Cancer Risk Again Linked to Cholesterol

High-grade Prostate Cancer Risk Again Linked to Cholesterol

Each 10 mg/dL increase in serum levels of total and HDL cholesterol are associated with a significant 5% and 14% increased risk of high-grade PCa, respectively.

Broader Statin Use More Effective for Atherosclerotic CVD Prevention

Broader Statin Use More Effective for Atherosclerotic CVD Prevention

Study compared guidelines for atherosclerotic cardiovascular disease prevention.

Some High-risk Heart Failure Patients Benefit From MRAs

Some High-risk Heart Failure Patients Benefit From MRAs

Mineralocorticoid receptor antagonists found to lower hospital readmission risk in patients with heart failure and concomitant diabetes or renal insufficiency.

Hemodialysis Patient Readmission Often Due to Pulmonary Edema

Hemodialysis Patient Readmission Often Due to Pulmonary Edema

Study finds that 44% of hospital readmissions among hemodialysis patients are related to pulmonary edema, with initial pulmonary edema-related hospitalization the strongest predictor for readmission due to the condition.

Atherosclerosis Develops in Pts Without Traditional CV Risk Factors

Atherosclerosis Develops in Pts Without Traditional CV Risk Factors

Male gender, age and LDL-C were all found to be independently related to atherosclerosis.

Meditation May Reduce Cardiovascular Risks

Meditation May Reduce Cardiovascular Risks

Given low cost and risk, meditation may be viable adjunct to guideline-directed treatment.

Lower BP Targets Reduce Cardiovascular Events Risk

Lower BP Targets Reduce Cardiovascular Events Risk

Intensive BP drops may lower cardiovascular risks in both patients with and without diabetes.

ACC: Treating Bleeding in Patients Taking Oral Anticoagulants

ACC: Treating Bleeding in Patients Taking Oral Anticoagulants

The ACC released decision pathways to help clinicians manage bleeding in patients taking oral anticoagulants.

Ceruloplasmin a Possible Marker of CKD in Sickle Cell Anemia

Ceruloplasmin a Possible Marker of CKD in Sickle Cell Anemia

Urinary ceruloplamin has potential to be a chronic kidney disease biomarker for patients with sickle cell anemia.

Acute Kidney Injury in CCU Patients Linked to Cystatin C

Acute Kidney Injury in CCU Patients Linked to Cystatin C

Among patients admitted to a coronary care unit, the highest quartile of serum cystatin C levels was associated with a 9.6-fold increased risk of AKI compared with the lowest quartile.

High ESA and Iron Doses Up CVD, Death Risk in Hemodialysis Patients

High ESA and Iron Doses Up CVD, Death Risk in Hemodialysis Patients

High doses of iron are associated with a significantly higher risk of cardiovascular disease, regardless of the dose of erythropoiesis-stimulating agent.

Severe Hypoglycemia a Red Flag for Cardiovascular Risks

Severe Hypoglycemia a Red Flag for Cardiovascular Risks

Severe hypoglycemia is associated with coronary heart disease, cardiovascular mortality, and cancer mortality.

CVD Hospitalization Rates Have Declined for Diabetes Patients

CVD Hospitalization Rates Have Declined for Diabetes Patients

For patients with diabetes, there was a significant decrease in hospitalization rates for acute coronary syndrome, cardiac dysrhythmia, heart failure, and certain strokes.

Coffee Benefits May Outweigh Risks

Coffee Benefits May Outweigh Risks

Coffee consumption was affiliated with more positives than negatives across a wide range of health outcomes.

Acute Kidney Injury Predicts Heart Failure

Acute Kidney Injury Predicts Heart Failure

In a study of hospitalized US veterans, AKI was associated with a 23% increased risk of heart failure compared with the absence of AKI.

Nut Consumption Tied With Lower Heart Disease Risk

Nut Consumption Tied With Lower Heart Disease Risk

Both total intake of nuts and consumption of peanuts/tree nuts and walnuts tied to lower risk.

Statins Reduce Risk of MACE in Patients With ASCVD

Statins Reduce Risk of MACE in Patients With ASCVD

Reduced frequency of MACE for patients receiving statins, especially high-intensity statins.

Waist-to-hip Ratio Predicts CV Mortality in Hemodialysis Patients

Waist-to-hip Ratio Predicts CV Mortality in Hemodialysis Patients

Each 0.1 increase in WHR is associated with a 1.7-fold increased risk of cardiovascular death.

Hypertension, Diabetes at Hemodialysis Initiation Increasing

Hypertension, Diabetes at Hemodialysis Initiation Increasing

From 1995 to 2015, the prevalence of hypertension and diabetes among patients starting hemodialysis increased from 67.9% to 87.6% and from 43.1% to 59.6%, respectively.

Post-Dialysis Survival Odds Better After CABG vs PCI

Post-Dialysis Survival Odds Better After CABG vs PCI

US veterans who underwent coronary artery bypass grafting versus percutaneous coronary intervention prior to starting dialysis had a 28% lower risk of death.

Statins May Raise Odds of Type 2 Diabetes in Those at High Risk

Statins May Raise Odds of Type 2 Diabetes in Those at High Risk

In any Diabetes Prevention Program treatment group, statin use tied to increased diabetes risk.

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