Overnight Saline Irrigation May Prevent Early NMIBC Recurrence

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Recurrence rate was 26.4% among patients who had overnight continuous saline irrigation following transurethral resection of bladder tumor vs 38.2% among those who did not.
Recurrence rate was 26.4% among patients who had overnight continuous saline irrigation following transurethral resection of bladder tumor vs 38.2% among those who did not.

Overnight continuous saline irrigation (OCSI) may offer an economical and safe way to prevent early recurrence of non-muscle invasive bladder cancer (NMIBC) following transurethral resection, according to investigators.

Jungmo Do, MD, and collaborators at Gyeongsang National University Hospital in Jinju, Korea retrospectively studied 332 patients who underwent transurethral resection of bladder tumor and cystoscopy every 12 weeks during the first year after surgery. Of the 332 patients, 120 had OCSI and 212 did not. The groups did not differ significantly with respect to age, gender, stage, tumor grade and size, smoking status, diabetes, hypertension and other characteristics.

The mean duration of time to initial recurrence was 302.85 days in the OCSI group compared with 277.19 days in the no irrigation group, the investigators reported in the Canadian Urological Association Journal. The recurrence rate was 26.4% in the OCSI group compared with 38.2% in the no-irrigation group.

The recurrence-free survival rate at 12 months following surgery was significantly higher in the OCSI than no-irrigation group.

Reference

Do J, Lee SW, Jeh SU, et al. Overnight continuous saline irrigation after transurethral resection for non-muscle-invasive bladder cancer is helpful in prevention of early recurrence. Can Urol Assoc J; 2018; published online ahead of print.

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