Thomas Coates

All articles by Thomas Coates

Management of Neutropenia

OVERVIEW: What every practitioner needs to know Neutropenia refers to an absolute neutrophil count (ANC) less than<1500/mm3. Under certain circumstances, the risk of bacterial infection due to neutropenia is related to the ANC but depends also upon the cause of the neutropenia. Adequacy of the marrow reserve pool is the most critical determinant of propensity…

Management of Disorders of Neutrophil Function: Chronic Granulomatous Disease

OVERVIEW: What every practitioner needs to know Are you sure your patient has chronic granulomatous disease? What are the typical findings for this disease? Chronic granulomatous disease (CGD) is a rare genetic disorder of phagocyte function characterized by recurrent, often life-threatening bacterial and fungal infections. Patients with CGD often present in the first years of…

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