Intensified Neoadjuvant Therapy Improves Outcomes in Very High-Risk Prostate Cancer
Investigators compared ADT plus abiraterone or docetaxel with ADT alone.
All articles by Natasha Persaud
Febuxostat May Help Stabilize Kidney Function in Chronic Kidney Disease
Major effects of febuxostat on renal outcome might be uric acid dependent, according to investigators.
Urinary Biomarkers May Improve Prediction of CKD Progression
Incorporating a combination of urinary biomarkers may help identify patients at the highest risk for CKD progression.
Bacillus Calmette-Guérin for Bladder Cancer Tied to Lower Dementia Risk
Investigators reviewed the latest studies examining the association between BCG administration and the risk of Alzheimer disease and other dementia in patients with bladder cancer.
High-Risk Weight Loss Increases Death Risk in Obese Patients With CKD
Trajectories of key clinical variables associated with weight loss distinguished patients with physiologic resilience vs vulnerability.
Inorganic Nitrate May Reduce Contrast-Induced Nephropathy Risk
Inorganic nitrate also reduced the risk for major adverse cardiac events in patients undergoing coronary angiography for non-ST-elevation acute coronary syndrome.
Semaglutide Beneficial in Obese Patients With HFpEF
Treatment with the glucagon-like-peptide-1 receptor agonist yielded substantial benefits in patients with heart failure with preserved ejection fraction.
BCR Endpoints an Unreliable Surrogate for Survival in Prostate Cancer Trials
Biochemical recurrence endpoints did not reliably predict overall survival in prostate cancer trials.
Multiple Factors Contribute to Testosterone Decline in Men
Mean testosterone concentration was relatively stable until age 70 years, investigators reported.
Prostate Cancer Survival Differs by Site of Visceral Metastases
Patients with prostate cancer who have visceral metastases limited to the lung have the best prognosis.
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