Michael P. Smith

All articles by Michael P. Smith

Mononeuritis multiplex

I. Mononeuritis Multiplex Mononeuritis Multiplex (MNM), also referred to as multiple mononeuropathy, is characterized by peripheral neuropathy of both the motor and sensory nerves of at least two different nerve trunks. Initially, the nerves are damaged in a nonsensical pattern leading to the description of a painful, asymmetric, asynchronous distribution. As the disease progresses, the…

Polyarteritis Nodosa

I. What every physician needs to know. Polyarteritis nodosa (PAN) is a systemic necrotizing vasculitis that predominantly affects medium-sized arteries. It is rare and usually ANCA-negative which is an important distinction in classification as a positive ANCA serology should have one consider other relatively more common medium to small vessel arterititis. Patients typically present with…

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