Melanie P. Hoenig

All articles by Melanie P. Hoenig

Diseases of Volume Regulation: Volume Overload

Does this patient have volume overload? Like volume depletion, the diagnosis of volume overload is made predominantly on clinical grounds. Laboratory tests are only supportive. Volume overload can result from primary renal salt retention, or the renal salt retention can be secondary to other processes. When the salt retention is primary, then the predominant manifestation…

Diseases of Volume Regulation: Volume Depletion

Does this patient have volume depletion? Is this patient volume depleted? The term “‘volume,” as used here, is used to describe extracellular fluid volume. Because the extracellular fluid is composed primarily of NaCl and water (with some NaHCO3 and some potassium), the term volume depletion reflects a deficiency in both NaCl and water. Another term…

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