Systemic Amyloidosis with Cutaneous Manifestations (Amyloidosis, Primary Systemic Amyloidosis, AL Amyloidosis)
Are You Confident of the Diagnosis? Systemic amyloidosis presenting with cutaneous manifestations is most commonly the result of primary systemic amyloidosis (Figure 1). Primary systemic amyloidosis can be subclassified into a type caused by an occult plasma cell dyscrasia, and a myeloma-associated type. Figure 1. Primary cutaneous amyloidosis in a patient without systemic involvement though…