RCC With NF2 Mutations Associated With Metastatic Disease, Poor Survival
Renal cell carcinoma patients with NF2 driver mutations often present with metastatic disease and have worse survival outcomes, research suggests.
All articles by Jessica Nye, PhD
Health Care Utilization Lower With Pembrolizumab-Axitinib Than With Ipilimumab-Nivolumab
Patients receiving first-line pembrolizumab-axitinib for metastatic renal cell carcinoma have lower health care resource utilization than patients receiving ipilimumab-nivolumab.
AUA Surveillance Guidelines May Improve Metastasis-Free Survival
Following the 2013 AUA guidelines on surveillance after partial nephrectomy can improve metastasis-free survival, a study suggests.
Characteristics of Renal Cell Carcinoma Differ According to Genetic Ancestry
Among patients with renal cell carcinoma, clinical presentation, extent of disease, and germline and somatic alterations differ according to genetic ancestry.
Researchers Characterize Gut Microbiome of Patients With mRCC and Sarcopenia
Sarcopenic patients with metastatic renal cell carcinoma have distinct bacterial populations that express metabolic pathways associated with a catabolic state.
High-Dose Dexamethasone May Be Harmful for Patients With COVID-19
Patients hospitalized with COVID-19 receiving supplemental oxygen had similar mortality outcomes with high- vs standard-dose dexamethasone, but evidence suggests higher dexamethasone doses may be associated with adverse outcomes. These study results were presented at IDWeek 2022, held from October 19 to 23, in Washington, DC. Anti-inflammatory agents, such as dexamethasone, are standard treatment for COVID-19…
PRESTO: ADT Intensification Prolongs PSA PFS in Biochemically Recurrent Prostate Cancer
Phase 3 results appear to support intensification of ADT in patients with biochemically recurrent prostate cancer.
Cancer Incidence and Risk Factors Among Immunocompromised Patients
The cancer incidence in certain immunocompromised patients was almost twice as high as the age-adjusted cancer incidence in the general population.
Monoclonal Antibodies Lower Risk of COVID-19 Hospitalization in Cancer Patients
There was no significant difference in post-infusion hospitalizations between patients with and without a history of cancer.
Perineural Invasion Linked to Biochemical Recurrence After Prostatectomy
Patients with perineural invasion had a 4-fold higher risk of biochemical recurrence.
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