Are You Confident of the Diagnosis? What you should be alert for in the history Congenital ichthyosiform erythroderma (CIE) may present in the newborn period as a collodion baby (milder than with lamellar ichthyosis) with ectropion and eclabium (Figure 1). As the collodion membrane is shed, patients develop diffuse erythema and fine, powdery scaling and…
Are You Confident of the Diagnosis? What you should be alert for in the history The newborn period is characterized by widespread blistering, denudation, and erythroderma that may lead to secondary infection and sepsis. Only focal hyperkeratosis is present at this age and misdiagnosis as epidermolysis bullosa is common. With age, blistering and denudation are…
Are You Confident of the Diagnosis? What to be alert for in the history Lichen striatus is characterized by the sudden onset of symptomatic, unilateral, linear lesions in young children. There is seldom an identifiable precipitant and some will have associated pruritus, especially if there is an atopic history. Most involve the upper or lower…
Are You Confident of the Diagnosis? What to be alert for in the history Lamellar ichthyosis (LI) most often presents in the newborn period as a collodion baby (Figure 1) with pronounced ectropion and eclabium. As the collodion membrane is shed, patients develop diffuse, plate-like scales and sometimes thickening of the palms and soles. The…
