Chronic Lymphocytic Leukemia
Chronic Lymphocytic Leukemia I. What every physician needs to know. Chronic Lymphocytic Leukemia (CLL) is the most common adult hematologic malignancy in the United States. Underlying the disease is a clonal expansion of functionally incompetent mature B-cells. Often associated are a number of different well-described cytogenetic abnormalities, which may be directly related to disease pathogenesis…