Niraparib Maintenance Failed to Improve Outcomes in Advanced Urothelial Carcinoma
The median progression-free survival was similar between the treatment arms.
The median progression-free survival was similar between the treatment arms.
The study’s primary endpoint was met, and neoadjuvant chemotherapy was considered well tolerated.
An AI tool outperformed NCCN guidelines for predicting biochemical failure, distant metastasis, prostate cancer-specific survival, and overall survival.
Compared with German and US patients, UK patients were less likely to be diagnosed with prostate cancer via routine screening.
The overall survival results were similar between the treatment arms for the overall cohort and for patients with PD-L1+ disease.
The 3-year prostate cancer-specific survival decreased significantly for insured patients.
Men nearly always outnumbered women, regardless of trial phase, cancer type, time period, or cancer incidence in the female population.
Cancer patients were less likely to receive critical care, whether they were on active anticancer treatment or not.
Long-term symptoms included shortness of breath, chronic fatigue, and neurocognitive dysfunction.
Dose-dense methotrexate plus vinblastine, doxorubicin, and cisplatin improved time to progression.