Drug Name:
ALLI OTC

Generic Name and Formulations:
Orlistat 60mg; caps.
Company:
GlaxoSmithKline
Therapeutic Use:
Indications for ALLI:
Adjunct to reduced-calorie, low-fat diet for weight loss in overweight adults.
Adult:
≥18yrs: 1 cap with each fat-containing meal. Max: 180mg/day. Also, take a multivitamin once daily at bedtime.
Children:
<18yrs: not recommended.
Contraindications:
Organ transplant. Chronic malabsorption syndrome. Cholestasis.
Warnings/Precautions:
Gallbladder disorder. Pancreatitis. Kidney stones. Seizures. Pregnancy, nursing mothers: not recommended.
Interactions:
Concomitant cyclosporine: not recommended. May decrease absorption of fat-soluble vitamins; supplement diet with a multivitamin (separate dosing by at least 2 hours). Variable effects when concomitant anticoagulants (eg, warfarin), amiodarone, antidiabetics, antiepileptics, antiretrovirals, thyroid drugs, or other weight loss products; monitor and dose adjustments may be needed.
Pharmacological Class:
Lipase inhibitor.
Adverse Reactions:
GI effects (oily spotting, flatus with discharge, fecal urgency, fatty/oily stools, oily evacuation, increased defecation, fecal incontinence); rare: hepatic injury.
How Supplied:
Caps—60, 90, 120, 170
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