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ALLI
Obesity
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Drug Name:

ALLI OTC

Generic Name and Formulations:
Orlistat 60mg; caps.

Company:
GlaxoSmithKline

Therapeutic Use:

Indications for ALLI:

Adjunct to reduced-calorie, low-fat diet for weight loss in overweight adults.

Adult:

≥18yrs: 1 cap with each fat-containing meal. Max: 180mg/day. Also, take a multivitamin once daily at bedtime.

Children:

<18yrs: not recommended.

Contraindications:

Organ transplant. Chronic malabsorption syndrome. Cholestasis.

Warnings/Precautions:

Gallbladder disorder. Pancreatitis. Kidney stones. Seizures. Pregnancy, nursing mothers: not recommended.

Interactions:

Concomitant cyclosporine: not recommended. May decrease absorption of fat-soluble vitamins; supplement diet with a multivitamin (separate dosing by at least 2 hours). Variable effects when concomitant anticoagulants (eg, warfarin), amiodarone, antidiabetics, antiepileptics, antiretrovirals, thyroid drugs, or other weight loss products; monitor and dose adjustments may be needed.

Pharmacological Class:

Lipase inhibitor.

Adverse Reactions:

GI effects (oily spotting, flatus with discharge, fecal urgency, fatty/oily stools, oily evacuation, increased defecation, fecal incontinence); rare: hepatic injury.

How Supplied:

Caps—60, 90, 120, 170

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