Searching for Surrogates: The Effort to Speed Up Drug Trials Surrogate endpoints can substantially shorten clinical trials and expedite approvals of new drugs, but they are elusive and sometimes controversial.
Albuminuria-Based CKD Screening Falls Short in At-Risk Populations Clinicians who test for albuminuria provide better evidence-based care to their patients than those who do not, research finds.
Prostate Cancer Biochemical Recurrence Risk Stratification Falls Short More stringent criteria are needed to define truly low-risk biochemical recurrence of prostate cancer following surgery and radiation treatment.
Urinary Biomarkers May Improve Prediction of CKD Progression Incorporating a combination of urinary biomarkers may help identify patients at the highest risk for CKD progression.
Lorundrostat Effective for Lowering BP in Uncontrolled Hypertension Changes in office systolic BP of −14.1, −13.2, −6.9, and −4.1 mm Hg seen with 100, 50, 12.5 mg once daily of lorundrostat and placebo
Prostate Cancer Outcomes Worse With Higher Periprostatic vs Serum Testosterone Local testosterone delivery to the prostate bed might be a better marker of post-prostatectomy outcomes than serum testosterone in some men.
Testicular Cancer Guidelines Updated Surveillance plays a major role in the management of men with cancer clinically confined to the testis.
HIV Is a Risk Factor for Acute Kidney Injury Even people with HIV that is well controlled with viral suppression are at increased risk for acute kidney injury.
Hyperuricemia Ups Risk for Non-Alcoholic Fatty Liver Disease A majority of patients with hyperuricemia had NAFLD, investigators reported.
Growth Differentiation Factor-15 Improves Prediction of Hemodialysis Outcomes Publish Date September 21, 2023
Risk for Intracerebral Hemorrhage May Be Transmissible Via Blood Transfusion Publish Date September 21, 2023
Lower SBP Targets After Endovascular Therapy Do Not Meet Futility Criteria Publish Date September 21, 2023
Less Aggressive Chemoradiation for MIBC Tested in Noncystectomy Patients Publish Date September 21, 2023
AACR Cancer Progress Report Reveals 33% Decrease in Cancer Death Rate, 1990 to 2020 Publish Date September 19, 2023