Study Reveals Epidemiology of Glomerulopathies in Brazil
Nephrol Dial Trans. 2006;21:3098-3105
Five-year data gathered by the Paulista Registry of Glomerulopathies in
A team led by Gianna Mastro-ianni-Kirsztajn, MD, of the Univer-sidade Federal de São Paulo, analyzed data from 2,086 patients for whom renal biopsies were performed because of a diagnosis of glomerular disease. The patients had a mean age of 34.5 years.
Among patients with primary glomerular disease, 29.7% had focal segmental glomerulosclerosis, 20.7% had membranous nephropathy, and 17.8% had IgA nephropathy. Another 9.1% had minimal change disease and 7% had membranoproliferative glomerulonephritis.
With respect to secondary glo-merular diseases, lupus nephritis predominated, occurring in 66.2% of cases, followed by post-infectious glomerulonephritis (12.5%) and diabetic nephropathy (6.2%).
Primary glomerular diseases occurred more frequently in males (55.1%), but secondary glomerular diseases were more common in females (71.8%). Nephrotic syndrome was a common presentation.
The authors wrote that their study “contributes to the understanding of the epidemiology of glomerular diseases in