PCNL Improves Renal Function in Late-Stage CKD Patients
J Endourol. 2008;22:1-6
Percutaneous nephrolithotomy (PCNL) improves the estimated glomerular filtration rate (eGFR) in patients with stage 5 CKD, but unexpected deterioration in renal function could occur in patients with earlier CKD stages, investigators in
The finding comes from a study of 185 patients with a preoperative eGFR less than 60 mL/min per 1.73 m2 and who underwent PCNL. In postoperative month 3, the mean eGFR was more than 60 mL/min per 1.73 m2 in 25% of the patients with CKD and less than 60 mL/min per 1.73 m2 in 75%.
All patients with stage 5 CKD improved to better CKD stages at the end of post-operative month 3. The researchers observed improved renal function in 50% of patients with stage 4 CKD but in only 25% of patients with stage 3 CKD. No patient in the study required dialysis.