Obesity Does Not Worsen Renal Transplant Outcomes
Obesity by itself is not associated with worse renal transplant outcomes, Australian investigators recently concluded.
Sean H. Chang, MD, of the
Underweight patients (BMI <18.5 kg/m2), however, had significantly worse late graft survival. More than five years post-transplant, underweight patients had a 70% increased risk of graft loss and an 89% increased risk of death-censored graft loss compared with normal-weight patients. This increased risk was due mainly to chronic allograft nephropathy, the investigators reported.
“Our study suggests that obesity per se should not be a contraindication for kidney transplantation,” the researchers concluded. “However, obese patients had higher unadjusted risks for death, due to its association with other risk factors. Careful pretransplant screening and management are therefore required.”