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Pulmonary Hypertension in HD Patients Increases Death Risk

June 18, 2009

Pulmonary hypertension (PHT) independently predicts greater mortality in hemodialysis (HD) patients, Israeli researchers report.
 

Hip-Fracture-Related Death Linked to CKD in the Elderly

June 18, 2009

Among older individuals, an estimated glomerular filtration rate (eGFR) below 45 mL/min/1.73 m2 is associated with a nearly twofold increased risk of hip-fracture-related mortality, according to British researchers.
 

Intermittent Hormonal Therapy for PCa May Have Benefits

June 18, 2009

Intermittent hormonal therapy (IHT) for men with locally advanced and metastatic prostate cancer is associated with no reduction in disease progression or survival, according to a European study.
 

Fatal Infections Probed in Pediatric LN Patients

May 07, 2009

Prior history of treatment with pulse methylprednisolone may increase the risk of fatal infection in pediatric lupus nephritis (LN) patients treated with IV cyclophosphamide (IVCY), researchers reported.
 

Pulse Pressure, Death Risk Linked in PD Patients

May 07, 2009

Elevated pulse pressure is associated with an increased risk of all-cause and cardiovascular death in patients on peritoneal dialysis (PD), according to a Canadian study.
 

CRP May Predict Survival in Metastatic RCC Patients

May 07, 2009

Pretreatment C-reactive protein (CRP) levels can be a prognostic marker for patients with metastatic renal cell carcinoma (RCC), a Japanese study suggests.
 

Sudden Death Risk Factors in Peritoneal Dialysis Patients Identified

April 02, 2009

Recent blood transfusions, male gender, and diabetes mellitus are independently associated with an increased risk of sudden death in patients on peritoneal dialysis (PD), a Chinese study concluded.
 

Recovery of Sexual Function Possible After Cryosurgery for PCa

April 02, 2009

Among prostate cancer patients who had no erectile dysfunction (ED) before undergoing cryosurgery, more than one third recovered full sexual function two years post-operatively, a British study found.
 

Postlithotripsy Agents Improve Stone Outcomes

April 02, 2009

Medical expulsive therapy (MET) following shockwave lithotripsy (SWL) results in a significant increase in successful treatment outcomes, according to Canadian researchers.
 

Hypertension, Acid Excretion Are Linked in Stone Formers

February 04, 2009

Kidney stone formers with essential hypertension have increased acid excretion, Italian researchers reported.
 

Urological Complications Not a Factor in Graft Survival

February 04, 2009

Urological complications occur frequently following transplantation of deceased cardiac donor (DCD) kidneys but do not affect graft survival, researchers in the Netherlands have concluded.
 

Urethral Strictures After HDR Brachytherapy Characterized

February 04, 2009

Bulbomembranous (BM) urethral strictures are the most common grade 2 or higher urinary toxicity following high dose rate brachytherapy (HDRB), according to Australian investigators.
 

Two Modes of Acupuncture May Work for Hot Flushes

January 22, 2009

Two modes of acupuncture appear to decrease the number and distress of hot flushes in men receiving castrational treatment for prostate cancer, according to a Swedish study.
 

Adjuvant Radiotherapy Found Not to Improve PCa Survival

January 22, 2009

Adjuvant radiotherapy following radical prostatectomy (RP) for prostate cancer has no effect on overall and cancer-specific survival, a Canadian team reports.
 

Chemokine Is Identified as a Marker for Acute Rejection

January 22, 2009

Measuring levels of the chemokine fractalkine in the urine is a noninvasive way to detect acute rejection of renal allografts, according to Chinese investigators. High levels are associated with steroid resistance and poor outcome.
 

Jaw Problem in Bisphosphonate Users May Be Underestimated

December 22, 2008

Bisphosphonate-associated osteonecrosis of the jaw (BP-ONJ) may be an underestimated problem in prostate cancer patients treated with zoledronate, German investigators suggest.
 

Data Support Epoetin Zeta Use in Hemodialysis Patients

December 22, 2008

Data from a German study suggest that IV-administered epoetin zeta—a new erythropoietin preparation—is safe for maintenance treatment of anemia in patients with end-stage renal disease.
 

Symptomatic RCC Predicts Worse Survival, Data Show

December 22, 2008

Patients with symptomatic renal cell carcinoma (RCC) have worse survival than those who have asymptomatic RCC detected incidentally, according to researchers from the Czech Republic.
 

Predictors of Cardiac Events After Renal Transplantation

November 01, 2008

Diabetic nephropathy and CVD prior to renal transplantation are the most important predictors of post-transplant cardiovascular events, researchers in The Netherlands conclude.
 

MMF Superior For Crescentric Lupus Nephritis, Data Show

November 01, 2008

Mycophenolate mofetil (MMF) is more effective as induction therapy than cyclophosphamide (CTX) in patients with crescentric lupus nephritis, Chinese investigators report.
 

Intravesical BCG Should Be Used First for Prophylaxis

November 01, 2008

Intravesical instillation of bacillus Calmette-Guérin (BCG) is most effective in the long term when selected as initial prophylactic treatment to prevent recurrence of superficial bladder cancer, according to a Japanese study.
 

Renal Impairment Increases Risk of Acute Renal Failure

September 02, 2008

CKD increases the risk of hospital-acquired acute renal failure (ARF), a study shows. The greater the degree of underlying renal impairment, the greater the ARF risk.
 

Severe AKI Has Implications for Long-Term Mortality

September 01, 2008

Severe acute kidney injury (AKI) is associated with significant long-term mortality, German investigators conclude.
 

UroVysion Not a Replacement for Cystoscopy, Study Finds

September 01, 2008

The UroVysion (UV) assay, which can diagnose urothelial cancer, cannot replace cystoscopy for monitoring patients with non-muscle-invasive bladder cancer. According to researchers in Sweden, the assay may be useful as a supplement to traditional measures for detecting carcinoma in situ (CIS).
 

Chair Test Measures Physical Functioning in CKD Patients

July 22, 2008

Evaluating how predialysis patients rise from a chair may provide a simple way to identify those who need help with muscle training and functional exercise, according to researchers in Sweden and Norway.
 

Mycophenolate Mofetil Works As Well As Standard Therapy

July 22, 2008

Six months of mycophenolate mofetil (MMF) treatment is as effective in the short term as conventional therapy for primary treatment of membranous nephropathy (MN) and focal segmental glomerulosclerosis (FSGS), a pilot study in India found.
 

Post-Tx Weight Changes May Increase Death Risk

July 22, 2008

Patient weight changes after renal transplantation may be a marker for poor survival, data suggest.
 

PCNL Improves Renal Function in Late-Stage CKD Patients

July 15, 2008

Percutaneous nephrolithotomy (PCNL) improves the estimated glomerular filtration rate (eGFR) in patients with stage 5 CKD, but unexpected deterioration in renal function could occur in patients with earlier CKD stages, investigators in Turkey report.
 

HIFU May Be Feasible Option for Low-Risk Prostate Cancer

July 15, 2008

Focal therapy with high-intensity focused ultrasound (HIFU) of localized prostate cancer provides immediate cancer control, comparable to that of other treatment modalities, according to Japanese researchers.
 

Broad Stroke Risk Benefit From BP-Lowering Observed

July 15, 2008

Antihypertensive treatment with perindopril prevents recurrent stroke in CKD patients across a wide spectrum of BP levels, according to Australian and Japanese researchers. They saw no evidence for a higher risk of stroke among individuals with low BP.
 

Renal Graft Survival Similar in Elderly, Younger Patients

May 06, 2008

Renal transplant recipients have similar death-censored graft survival regardless of age, according to researchers in Norway.
 

Repeat PSA Tests May Aid Prostate Biopsy Decisions

May 06, 2008

Following an initial PSA test result of 3.0-19.99 ng/mL in men aged 50-70 years, a repeat PSA test within seven weeks allows for more accurate assessment as to whether a biopsy will reveal prostate cancer, a British team reports.
 

Some Patients May Receive Renal Transplants Needlessly

May 01, 2008

It may be reasonable to postpone renal transplantation in patients with certain types of renal failure because late recovery of kidney function might occur, according to British researchers.
 

Alcohol Consumption Cuts ESRD Risk in Chinese Men

May 01, 2008

Researchers who studied a large cohort of Chinese men found an inverse relationship between alcohol consumption and end-stage renal disease (ESRD).
 

Bladder CIS Extent Predicts Post-BCG Disease Progression

May 01, 2008

Treatment with bacillus Calmette-Guérin (BCG) is effective for carcinoma in situ (CIS) of the bladder, according to Japanese researchers.
 

Ascorbate Deficiency Common in Australian PD Patients

April 11, 2008

Ascorbate deficiency is common among peritoneal dialysis (PD) patients and can be identified readily with serum ascorbate measurements, researchers in Australia report.
 

'Remarkably High' Prevalence of CKD Found in Thailand

April 10, 2008

Thailand has a "remarkably high" prevalence of CKD among individuals aged 35 years and older, according to Thai and Australian researchers.
 

HoLEP Efficacy for BPH Increases with Prostate Size

April 10, 2008

The efficacy of holmium laser enucleation of the prostate (HoLEP) in the treatment of symptomatic BPH increases with prostate size, according to researchers in India.
 

Lower BPH Risk Linked to Greater Vegetable Intake

April 10, 2008

A diet high in vegetable intake is associated with a lower risk of surgically treated BPH, according to Australian researchers.
 

High-Grade Prostate Cancer Has a Poor Prognosis

February 27, 2008

Patients with Gleason 8-10 prostate tumors have a poor prognosis, according to researchers at the Henri Mondor University Hospital in Créteil, France.
 

Time on Dialysis Correlates with Delayed Graft Function

February 27, 2008

Increasing duration of dialysis is associated with an increased risk of delayed graft function (DGF) following renal transplantation, researchers in Canada have found.
 

Low Dihydrotestosterone May Decrease PCa Survival

February 27, 2008

Low dihydrotestosterone (DHT) may be associated with decreased survival in prostate cancer patients, according to researchers in Sweden.
 

Urotensin II Predicts Lower Death Risk in CKD Patients

February 27, 2008

Elevated plasma levels of urotensin II (UTN) predicts a lower risk of death from all causes and cardiovascular causes in CKD patients, Italian researchers conclude.
 

MMF Similar to Conventional Therapies for MN, FSGS

January 01, 2008

A six-month course of treatment with mycophenolate mofetil (MMF) is as effective as conventional therapies for treating membranous nephropathy (MN) and focal segmental glomerulosclerosis (FSGS), according to a pilot study conducted in India.
 

In Taiwan, Most Incontinent Women Do Not Seek Help

January 01, 2008

Almost 30% of Taiwanese women aged 60 years and older suffer from urinary incontinence (UI), but most do not visit a doctor for the condition, a study found.
 

Antibody Assay Could Aid in Assessing Prostate Disease

January 01, 2008

Using an assay they developed to detect antibodies to Propionibacterium acnes bacteria, researchers have found a link between these bacteria and development of inflammation-related prostate diseases.
 

Obesity Does Not Worsen Renal Transplant Outcomes

January 01, 2008

Obesity by itself is not associated with worse renal transplant outcomes, Australian investigators recently concluded.
 

One Third of Standard BCG Dose May Be Sufficient

November 01, 2007

One third of the standard dose of bacillus Calmette-Guérin (BCG) could be recommended as adjuvant treatment for intermediate-risk superficial bladder tumors, Spanish researchers say.
 

PSA Density Predicts PSA Velocity, UK Study Shows

November 01, 2007

PSA density is an independent determinant of PSA velocity in untreated localized prostate cancer, a study in the UK concluded.
 

Older Age May Increase CKD Risk in Live Kidney Donors

November 01, 2007

Older age and hypertension increase the risk of renal impairment among live kidney donors, according to South Korean researchers.
 

Ethanol May Ease Secondary Hyperparathyroidism Post-Tx

November 01, 2007

Percutaneous ethanol injection therapy (PEIT) is a useful and safe treatment alternative for patients with persistent post-transplant secondary hyperparathyroidism, researchers in Argentina report.
 

Treatment Manages CMV in Transplant Recipients

October 23, 2007

Preemptive ganciclovir treatment of cytomegalovirus (CMV) infection in simultaneous pancreas-kidney (SPK) transplant recipients appears to be associated with good long-term outcomes, German researchers report.
 

Nystatin Prophylaxis May Benefit CAPD Patients

October 23, 2007

Oral nystatin prophylaxis may prevent antibiotic-related fungal peritonitis (AR-FP) in patients receiving continuous ambulatory peritoneal dialysis (CAPD), researchers in Hong Kong concluded.
 

Canadian Renal Transplant Data Show Race Disparities

October 23, 2007

Among Canadian dialysis patients, those of East Asian and Indo Asian origin are less likely to receive a renal transplant than white patients, data show.
 

RRT-Treated ARF in Scotland More Common Than Expected

October 23, 2007

Acute renal failure (ARF) in Scotland occurs more frequently than previously thought, according to new research.
 

Urinary Incontinence Risk Linked to Physical Activity

September 01, 2007

Higher levels of physical activity are independently related to a lower self-reported prevalence of urinary incontinence in a community-dwelling population aged 70 years and older, a Japanese study recently showed.
 

Low Vitamin D Levels Highly Prevalent in Dialysis Patients

September 01, 2007

A study in Argentina found that vitamin D insufficiency and deficiency are highly prevalent in hemodialysis (HD) patients at the end of winter.
 

Chemotherapy Plus Radiotherapy May Enable Bladder Preservation

August 06, 2007

Combining cisplatin-based intra-arterial chemotherapy and radiotherapy is effective long-term for local invasive bladder carcinoma, according to a Japanese study.
 

Calcitriol May Have Role in HRPC Salvage Therapy

August 01, 2007

High-dose calcitriol and docetaxel, each given separately one day a week for six weeks, appear to be an effective and well-tolerated combination for men living with metastatic hormone-refractory prostate cancer (HRPC) previously treated with docetaxel-based chemotherapy, Italian investigators conclude.
 

Study: CRP Levels May Identify High-Grade VUR

August 01, 2007

A fever of 38.5º C or higher may predict which children have vesicoureteral reflux (VUR), and C-reactive protein (CRP) levels above 50 mg/L may identify children with high-grade VUR, a Turkish study found.
 

Greater Stone Density Predicts SWL Failure

August 01, 2007

High renal-stone density and elevated BMI decrease the likelihood of stone disintegration with shock wave lithotripsy (SWL), Egyptian researchers conclude.
 

Anal Cancer Risk Higher in Solid Organ Recipients

August 01, 2007

Recipients of solid organ transplants have a higher rate of anal cancer, but not colorectal cancer, than the general population, according to an Austrian study.
 

Bladder Cancer Risk Higher in TURP-Treated BPH Patients

July 01, 2007

A study of Swedish men with BPH found no excess risk of bladder cancer, but did show that the likelihood of the malignancy is elevated in those who undergo transurethral resection of the prostate (TURP), especially men with comorbid genitourinary tract conditions.
 

Vaginal Tape Works With or Without Sphincter Deficiency

July 01, 2007

Tension-free vaginal tape (TVT) is similarly effective for treating stress urinary incontinence in women with and without intrinsic sphincter deficiency, a South Korean study found.
 

Malnourished Children Found to Have Smaller Kidneys

July 01, 2007

Malnourished children have smaller kidneys, and body height is the main determinant of their kidney length and volume, Turkish investigators conclude.
 

Folate Supplementation May Benefit Hemodialysis Patients

July 01, 2007

Early folate supplementation by lowering plasma total homocysteine (tHcy) may prevent cardiovascular deterioration in patients with chronic renal failure, according to researchers in Brazil.
 

Asians Are More Likely Than Whites to Choose PD

June 20, 2007

A Canadian study shows that East Asian and Indo Asian patients with end-stage renal disease (ESRD) are more likely than white patients to initiate dialysis treatment on peritoneal dialysis (PD).
 

Hydronephrosis Prolongs Stone Clearance Time

May 08, 2007

In patients with solitary distal ureteral stones, hydronephrosis is associated with prolonged stone clearance following shock wave lithotripsy (SWL), but the degree of hydronephrosis caused by the stones does not affect overall SWL outcome.
 

Risk Factors for Post-TVT Voiding Problems Identified

May 08, 2007

Age and maximal peak flow rate before tension-free vaginal tape (TVT) placement are independent risk factors for postoperative voiding dysfunction, a French study found.
 

Higher Prostate Cancer Risk Found in BPH Drug Users

May 08, 2007

Men who take finasteride or alpha blockers for BPH are at higher risk of prostate cancer than non-users, investigators in Finland conclude.
 

Mitomycin C, BCG Comparable For High-Risk Bladder Cancer

May 08, 2007

A 10-year follow-up study of patients with high-risk bladder cancer shows that mitomycin C (MMC) and bacillus Calmette-Guérin (BCG) have similar effects on disease progression, need for subsequent treatment, and survival.
 

PCa Risk Not Lower in Men with Fluctuating PSA Level

May 08, 2007

Contrary to what is commonly thought, the risk of having a positive repeat prostate biopsy is no lower for men with a fluctuating PSA level than it is for those with a steady or steadily increasing PSA level.
 

CRP Predicts PD-Associated Peritonitis Outcomes

April 25, 2007

Higher levels of C-reactive protein (CRP) are independently associated with adverse outcomes in peritonitis associated with peritoneal dialysis (PD), according to Canadian researchers.
 

Prostate Cancer Risk Higher in Blacks than Whites

April 25, 2007

Prostate cancer is three times more likely to develop in black men than white men in the United Kingdom, although the risk is lower than that of black men in the United States, researchers in England conclude.
 

Gallstone Disease in Renal Transplant Patients Defined

April 25, 2007

The incidence of gallstone disease in patients on a kidney transplantation waiting list is similar to that of the general population, but in transplant patients, the complications may be severe, researchers in Finland report. They recommend screening and treatment of pre- and post-transplantation gallstone disease.
 

Sildenafil Shows Promise for Premature Ejaculation

April 25, 2007

Sildenafil is safe and more effective than paroxetine and the squeeze technique for treating premature ejaculation, according to a Chinese study.
 

Renal Decline Is Unusual After Obstruction Relief

March 01, 2007

Progressive deterioration in renal function is unusual following relief of obstructive nephropathy in most patients over a three-year period, according to British researchers.
 

Laparoscopic Nephrectomies Safe Despite Comorbidities

March 01, 2007

Laparocopic nephrectomy can be performed safely and effectively in patients with three or more comorbidities, a Japanese study shows.
 

Dyslipidemias, Obesity, and Smoking Raise CKD Risk

March 01, 2007

Like hypertension and diabetes, dyslipidemias, obesity, and current smoking are among the independent risk factors for CKD, according to Japanese investigators.
 

Anesthetic Spray May Work For Premature Ejaculation

March 01, 2007

An aerosol anesthetic spray may be a safe and effective treatment for premature ejaculation (PE), British researchers report.
 

Valve Calcifications Linked to Mineral Abnormalities

February 01, 2007

Data from a Moroccan study implicate calcium and phosphate metabolism abnormalities in the pathogenesis of heart valve calcifications in patients on hemodialysis.
 

Repeated Botox Injections Have a Persistent Effect

February 01, 2007

Repeated injections of botulinum toxin A into the detrusor muscle have a persistent beneficial effect on neurogenic detrusor overactivity, according to a study by French and Swiss investigators.
 

Simple Enucleation for Small RCC Tumors Safe, Acceptable

February 01, 2007

Simple enucleation is a safe and acceptable nephron-sparing treatment for pT1a renal cell carcinoma (RCC), Italian researchers say.
 

Small Renal Tumors Treatable with Radiofrequency Ablation

January 01, 2007

Radiofrequency ablation (RFA) of small renal tumors is a promising alternative to surgery, investigators in Poland report.
 

Study Reveals Epidemiology of Glomerulopathies in Brazil

January 01, 2007

Five-year data gathered by the Paulista Registry of Glomerulopathies in São Paulo, Brazil, shows that focal and segmental glomerulosclerosis is the most common primary glomerular disease, followed by membranous nephropathy and IgA nephropathy.
 

HIFU May Be Feasible For High-Risk Prostate Cancer

January 01, 2007

High-intensity focused ultrasound (HIFU) can produce good short-term outcomes in patients with high-risk prostate cancer, researchers in Italy conclude.
 

Hypoalbuminemia Predicts Hypotension During Dialysis

January 01, 2007

Hypoalbuminemia is a risk factor for hypotension during hemodialysis, Japanese researchers report.
 

Low-Osmolar Contrast Agent Is Safer For the Kidneys

January 01, 2007

A large Swedish study of patients undergoing coronary procedures shows that renal failure is more likely to develop with the use of an iso-osmolar rather than low-osmolar contrast media.
 

Spironolactone Beneficial In Type 2 Diabetic Nephropathy

December 01, 2006

Adding spironolactone to an ACE inhibitor or angiotensin II receptor blocker (ARB) is associated with a marked and sustained antiproteinuric effect in type 2 diabetics, researchers in the Netherlands found.
 

Cyclosporine A May Benefit Some Nephrotic Patients

December 01, 2006

Twelve months of therapy with cyclosporine (CyA) with or without prednisolone induces remission in most nephrotic patients with membranous nephropathy of moderate severity, investigators in Greece conclude.
 

MRI-Guided Biopsy May Increase Accuracy of PCa Diagnosis

December 01, 2006

MRI-guided biopsy of the prostate may improve the diagnostic accuracy in men with elevated or rising PSA levels following previous negative transrectal ultrasound (TRUS)-guided biopsies, German researchers report.
 

Ethanol Injections Effective for Urinary Retention

December 01, 2006

Transurethral ethanol injection into the prostate (TUEIP) is an effective treatment for persistent urinary retention resulting from prostatic obstruction, according to a Japanese study.
 

Acute Graft Pyelonephritis Raises Complication Risks

November 01, 2006

Acute graft pyelonephritis (AGPN) increases the risk of bacteremia, acute rejection, and cytomegalovirus (CMV) disease, but it does not independently contribute to poor graft or patient survival, researchers in India report.
 

Heavy Weight Increases Renal Graft Loss Risk in Asians

November 01, 2006

Higher BMI is associated with an increased risk of renal graft loss in Asian transplant recipients, researchers in Hong Kong report.
 

Q2W Dosing of Darbepoetin Alfa is Safe and Effective

November 01, 2006

Darbepoetin alfa administered once every two weeks (Q2W) safely and effectively treats anemia in hemodialysis patients without having to increase the dose, according to researchers in Portugal.
 

Heart Screening Justified In Diabetic Nephropathy Patients

November 01, 2006

Patients with diabetic nephropathy who are candidates for kidney or kidney- pancreas transplantation should be screened routinely with coronary angiography, researchers in Norway conclude.
 

 

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