Post-MI AKI May Worsen Survival

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VANCOUVER, B.C.—Patients who experience moderate or severe acute kidney injury (AKI) after suffering an acute myocardial infarction (AMI) may have worse short- and mid-term survival than patients who not have AKI, data suggest.

Portuguese researchers studied 264 patients with AMI hospital in Hospital de Santa Maria in Lisbon. AKI occurred in 65 (24.6%). The investigators stratified AKI according to RIFLE (Risk, Injury, Failure, Loss and End-stage renal disease) criteria. Of the 264 patients, 8.7%, 8.3%, and 7.6% fell into the Risk, Injury, and Failure classes, respectively.

Compared with patients who did not have AKI, those with Injury and Failure class AKI were at 5.36 and 13.34 times increased risk of dying in the hospital. Risk class AKI did not increase the risk of in-hospital mortality.

In addition, after adjusting for age, gender, race, and cormorbidities such as hypertension, diabetes, AKI increased three-year mortality.

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