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Biomarker Assays for Prostate Cancer Management

Should biomarker assays be an integral part of prostate cancer patient care?

Urology News

Latest Urology News

Prostate Cancer IMRT for Prostate Cancer Radiation Therapy Soars

IMRT for Prostate Cancer Radiation Therapy Soars

Use of intensity-modulated radiation therapy for prostate cancer increased from 3.5% to 64% from 2002 to 2012.

Prostate Cancer Prostate Cancer Risk Lower in NSAID Users

Prostate Cancer Risk Lower in NSAID Users

In a case-control study, men who had ever used non-steroid anti-inflammatory drugs had a 23% decreased risk of prostate cancer.

Bladder Cancer FGFR3-TACC3 Gene Fusion Found in Bladder Cancer

FGFR3-TACC3 Gene Fusion Found in Bladder Cancer

The researchers note that TACC3 is a mitotic spindle protein required for accurate segregation of chromosomes, and errors in segregation can lead to aneuploidy, contributing to cancer progression.

Prostate Cancer Prostate Cancer Active Surveillance Use Low, But Increasing

Prostate Cancer Active Surveillance Use Low, But Increasing

Use of active surveillance for very low-risk prostate cancer rose from 11.6% of patients in 2010 to 27.3% in 2013, study finds.

Prostate Cancer First Metastasis Site Predicts Prostate Cancer-Specific Survival

First Metastasis Site Predicts Prostate Cancer-Specific Survival

Following curative treatment for localized PCa, 5-year PCa-specific survival rates are higher for patients with initial lymph node or locoregional metastases versus initial metastases in bone only or in multiple sites.

Prostate Cancer Additions to Standard Care in High-Risk PCa May Up Survival

Additions to Standard Care in High-Risk PCa May Up Survival

Findings from this comparative study indicate a favorable failure-free survival and progression-free survival with Standard of Care plus abiraterone acetate and prednisone.

Kidney Cancer Immunotherapy Superior to Sunitinib for Front-Line mRCC Treatment

Immunotherapy Superior to Sunitinib for Front-Line mRCC Treatment

Checkpoint inhibitor combination of nivolumab plus ipilimumab improved progression-free and overall survival compared with sunitinib.

Prostate Cancer Proximal PSA Predicts Prostate Cancer Metastasis Risk

Proximal PSA Predicts Prostate Cancer Metastasis Risk

PSA levels of 10 ng/mL or higher in men who have biochemically recurrent PCa after radical prostatectomy and a PSADT less than 12 months are at imminent risk for metastatic disease.

Urology Universal Sequencing of Cancer-related Genes Beneficial for Tx

Universal Sequencing of Cancer-related Genes Beneficial for Tx

Knowledge of these additional mutations can help guide therapeutic and preventive interventions.

Prostate Cancer Toxicity Similar for 6- and 2- Fraction HDR Brachytherapy in PCa

Toxicity Similar for 6- and 2- Fraction HDR Brachytherapy in PCa

The researchers found that there was no difference between the 6- and 2-fraction groups in baseline and post-implantation IPSS scores.

Kidney Cancer Upfront Cabozantinib for Advanced RCC Improves Outcomes

Upfront Cabozantinib for Advanced RCC Improves Outcomes

Cabozantinib reduced the risk of disease progression or death compared with sunitinib among patients with previously untreated advanced renal cell carcinoma.

Kidney Cancer Early NLR Changes Predict mRCC Immunotherapy Outcomes

Early NLR Changes Predict mRCC Immunotherapy Outcomes

Rises and decreases in neutrophil-to-lymphocyte ratio at 6 weeks after treatment with anti-PD-1/PD-L1 immune checkpoint blockade is associated with progression-free and overall survival.

Urology Perioperative Management Crucial in Surgical Resident Malpractice

Perioperative Management Crucial in Surgical Resident Malpractice

Cases more often questioned perioperative medical knowledge, decision making errors, and injuries than intraoperative errors and injuries.

Prostate Cancer Prostate Cancer Screening Saves Lives, New Analysis Shows

Prostate Cancer Screening Saves Lives, New Analysis Shows

A European trial found a survival benefit from PCa screening and a US trial did not, but a new analysis finds that both trials provide compatible evidence that screening decreases PCa mortality.

Prostate Cancer Prostate Cancer ADT Linked With Cardiovascular Risks, Depression

Prostate Cancer ADT Linked With Cardiovascular Risks, Depression

In a study, the risk for heart failure was 81% higher among patients who received androgen deprivation therapy.

Urinary Tract Infections (UTI) Drug Approved for Complicated Urinary Tract Infections

Drug Approved for Complicated Urinary Tract Infections

Vabomere, which combines meropenem and vaborbactam, demonstrated superior efficacy to piperacillin/tazobactam.

Erectile Dysfunction (ED) Erectile Dysfunction Afflicts More Than Half of Men With Diabetes

Erectile Dysfunction Afflicts More Than Half of Men With Diabetes

Meta-analysis of studies conducted around the world found that men with diabetes have more than 3.5 times increased risk for erectile dysfunction.

Kidney Cancer Energy Dense Diet Increases Obesity-Related Cancer Risk

Energy Dense Diet Increases Obesity-Related Cancer Risk

The increased risk for obesity-related cancer was seen among women who were normal weight at enrollment.

Reproductive Medicine Zika Virus Remains in Semen Shorter Than 6 Months

Zika Virus Remains in Semen Shorter Than 6 Months

The maximum duration of detectable Zika in semen in the study was 45 days.

Kidney Cancer Opioids Highly Prescribed to Cancer Survivors

Opioids Highly Prescribed to Cancer Survivors

The researchers found that the rate of opioid prescribing was 1.22 times higher among survivors than among matched controls.