Gemcitabine might be a second-line treatment option for patients with high-risk non-muscle-invasive bladder cancer (BC) who fail therapy with bacille Calmette-Guérin (BCG), according to Italian researchers.

BCG cut the risk of cancer-related death risk by 53% versus epirubicin.

It is associated with a higher risk of recurrence and death from upper tract urothelial carcinoma.

The condition is more likely to develop in men with high interleukin-6 or C-reactive protein levels.

Decreased peak flow rate and a history of hypertension and/or diabetes are significantly associated with CKD in men with lower urinary tract symptoms (LUTS) secondary to benign prostatic hyperplasia (BPH), according to investigators in Seoul, Korea.

Dutasteride treatment for benign prostatic hyperplasia (BPH) is associated with a significant increase in serum testosterone and a significant decrease in BMI among men with relatively lower baseline serum testosterone levels, researchers reported in BJU International (2009; published online ahead of print).

Older men with restless leg syndrome (RLS) are more likely to have erectile dysfunction (ED) than men without RLS—and dopamine may be the common denominator, according to a study.

Black men and Asian men are less likely to have severe erectile dysfunction (ED) than white men, according to a study of 78,445 men aged 45 to 69 years who were not diagnosed with prostate cancer.

LYON, FRANCE—Israeli researchers have reported promising preliminary results using low-intensity shock wave therapy to treat vasculogenic erectile dysfunction (ED).

Pentoxifylline sustained-release (PTX-SR) is moderately effective reducing penile curvature and plaque volume in men suffering from early Peyronie's disease, researchers concluded.

PHILADELPHIA—Erectile dysfunction (ED) is more common in patients with rheumatic disease—especially rheumatoid arthritis (RA)—than in the general population, according to new findings by an Irish research team.

The histologic type of renal cell carcinoma (RCC) arising in patients with end-stage renal disease (ESRD) may be related to the time on dialysis, according to a study.

Robot-assisted partial nephrectomy (RAPN) is a safe and effective approach for nephron-sparing surgery (NSS) that is capable of providing patients with excellent short-term oncologic outcomes, according to the largest RAPN experience described to date.

Administering sorafenib prior to nephrectomy for renal cell carcinoma (RCC) can reduce the size of the primary tumor with adding to the risk of surgery, according to researchers at the University of North Carolina at Chapel Hill.

During a five-year period, stones were diagnosed in 4.9% of obese and 2.6% of non-obese subjects.

Diabetes, hypertension, frequent UTIs, the formation of struvite stones, and allopurinol use may predict the development of CKD among individuals who have had kidney stones, researchers reported in the American Journal of Kidney Diseases (2009; published online ahead of print).

Among individuals who have had kidney stones, diabetes, hypertension, frequent UTIs, the formation of struvite stones, and allopurinol use may predict the development of CKD, according to researchers.

Lithostat (acetohydroxamic acid), the only urease inhibitor available for urea-splitting urinary infections in association with struvite stones, is available again at pharmacies nationwide, according to the drug's marketer, Mission Pharmacal.

The protective effect of a DASH-style diet was similar for men and women regardless of age and BMI.

The associated cost is a potential reason for undertreatment.

Only 24.4% of patients aged 45 years and older take drugs for the condition, according to researchers.

Study findings at 12 months showed prolonged significant improvements in objective urinary parameters.

Solifenacin-treated patients experienced less dry mouth than those taking oxybutynin immediate release.

Percutaneous tibial nerve stimulation may be considered an alternative treatment for overactive bladder (OAB), researchers reported in the Journal of Urology (2009;182:1055-1061).

Men suffering from premature ejaculation had a sixfold increase in intravaginal ejaculatory time.

Dapoxetine shows efficacy in the treatment of premature ejaculation (PE), according to a new study that researchers say is the most comprehensive to date examining a pharmacologic treatment for PE.

ORLANDO—For the first time, clinicians have an evidence-based definition of premature ejaculation (PE).

A panel of sexual health authorities has developed what they say is the first evidence-based definition of premature ejaculation (PE).

MILAN—Female partners of men with premature ejaculation (PE) seem to benefit when the condition is treated with dapoxetine (DPX), according to findings presented here at the European Association of Urology 23rd Congress.

SAN FRANCISCO—Chemotherapy is associated with a significantly decreased risk of death from prostate cancer (PCa) among elderly men with Stage IV prostate cancer treated with androgen deprivation therapy (ADT), new findings suggest.

Studies provide conflicting results on the influence of dietary fat, but caloric intake may be the key, researcher says.

SAN FRANCISCO—Obesity is associated with higher positive surgical margin (PSM) rates after robotic-assisted laparoscopic prostatectomy (RALP), a study found.

SAN FRANCISCO—Cumulative mortality from prostate cancer 15 years after radical prostatectomy is six times lower than death from other causes, according to study findings presented here at the Genitourinary Cancers Symposium. Among men older than 65 years at the time of surgery, cumulative 15-year mortality is 10 times lower.

SAN FRANCISCO—Skeletal-related events (SREs) in patients with metastatic hormone-refractory prostate cancer (mHRPC) are mostly due to bony metastatic disease and not decreased bone mineral density (BMD), according to British researchers.

SAN FRANCISCO—The prostate cancer gene 3 (PCA3) molecular urine test is more accurate than the PSA test in predicting outcomes of repeat biopsies, new findings confirm.

Onset of statin use is associated with a significant reduction in serum PSA level, data suggest.

A study of a large multiethnic cohort found that African-American men had a higher prevalence of PSA screening than white and Latino men.

After a median of 32 months, PSA was undetectable in 12% of patients.

The likelihood of an abnormal finding is 46% lower in obese men than normal-weight men, study shows

Statin therapy may induce primary hypogonadism and should be considered a possible confounding factor when evaluating testosterone levels in patients with erectile dysfunction (ED), according to Italian researchers.

Adult circumcision appears to have little clinical benefit in terms of preventing urinary tract infections, sexual transmitted diseases, and penile cancer, according to a systematic review of eight studies.

Single-surgeon series shows it can decrease operative time compared with traditional procedures.

The American Urological Association (AUA) has formed a Male Circumcision Task Force and is collaborating with major international health care agencies to bolster adult male circumcision services in sub-Saharan Africa to combat the spread of AIDS.

Men with severe oligoasthenospermia may be able to avoid testicular sperm retrieval, data suggest.

Before surgery, 6% of women tested negative on the cough stress test compared with 98% at 12 months .

Four weeks after treatment, 51% of subjects had complete continence.

Before surgery, 6% of women tested negative on the cough stress test compared with 98% at 12 months .

Intradetrusor injections of botulinum toxin type A may be an effective treatment for refractory idiopathic detrusor overactivity.

Study findings at 12 months showed prolonged significant improvements in objective urinary parameters.

The problems developed following 20% of major urologic procedures in patients with chronic bacteriuria.

In a study, only 3% of ESBL-producing Escherhicia coli isolates were resistant to fosfomycin.

It is associated with fewer recurrences than lactobacilli, but it increases antibiotic resistance.

A non-pathogenic strain of E. coli lowered the UTI rate in catheterized men with neurogenic bladder.

A non-pathogenic strain of E. coli lowered the UTI rate in catheterized men with neurogenic bladder.