Transplantation

Are Doctors Discarding Suitable Kidneys?

Are Doctors Discarding Suitable Kidneys?

Less than perfect older kidneys may still be suitable for transplantation.

Robotic Kidney Transplantation Safe, Feasible

Robotic Kidney Transplantation Safe, Feasible

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Robotic-assisted kidney transplantation is associated with a low complication rate and excellent graft function, European study shows.

Racial-Ethnic Gap in Living Donor Kidney Transplantation Widens

Racial-Ethnic Gap in Living Donor Kidney Transplantation Widens

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New findings suggest that national strategies have failed to correct racial/ethnic disparities in live donor kidney transplantation.

Excess Death Risk in ESRD Has Declined

Excess Death Risk in ESRD Has Declined

Decrease in excess risk of all-cause mortality from 1995 to 2013 for those with end-stage renal disease.

Targeting Ups Nanoparticle Accumulation in Graft Endothelial Cells

Targeting Ups Nanoparticle Accumulation in Graft Endothelial Cells

Altering the surface of an anti-CD31 antibody helps NPs administer therapeutics to ECs.

Variables Affecting Deceased-Donor Kidney Acceptance Rates

Variables Affecting Deceased-Donor Kidney Acceptance Rates

Data that shed light on the allograft decision process may ultimately help transplant teams navigate their expanding waiting lists.

Monoclonal Antibodies Reduce Injury of Renal Allografts

Monoclonal Antibodies Reduce Injury of Renal Allografts

In animal model, anti-CD47 monoclonal antibody group had decease in injury of renal allografts.

Nonmedical Attributes Tied to Later Kidney Transplant Waits

Nonmedical Attributes Tied to Later Kidney Transplant Waits

African-Americans less likely to be wait-listed; higher income positively associated with wait-listing.

Causes of Most Kidney Transplant Patient Deaths Reported as Unknown

Causes of Most Kidney Transplant Patient Deaths Reported as Unknown

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Among kidney transplant recipients who died with a functioning graft, the cause of death was reported as unknown for 64% of them.

Intensive Home HD, Deceased-Donor Transplants Offer Similar Survival

Intensive Home HD, Deceased-Donor Transplants Offer Similar Survival

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After adjusting for confounders, patients on intensive home hemodialysis and recipients of deceased-donor kidneys showed no significant difference in death risk

Kidney Graft Loss Risk Not Associated With Vitamin D Deficiency

Kidney Graft Loss Risk Not Associated With Vitamin D Deficiency

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In a study 383 kidney transplant recipients, low levels of 25-hydroxyvitamin D were not associated with an increased risk of graft loss following transplantation.

Skin Cancer After Organ Transplant Declining

Skin Cancer After Organ Transplant Declining

Standardized incidence ratio peaked in patients who underwent transplantation in 1983-1987 period.

Melanoma Staging System Updated

Melanoma Staging System Updated

Key changes include new N category descriptors, more stage III subgroups, new M1D designation.

Study Identifies Possible Way to Reduce Kidney Discard Rate

Study Identifies Possible Way to Reduce Kidney Discard Rate

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Limiting cold ischemia times could increase the use of renal allografts donated from patients after death from cardiovascular causes, researchers say.

Recurrent UTIs Worsen Kidney Transplant Outcomes

Recurrent UTIs Worsen Kidney Transplant Outcomes

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Kidney transplant recipients who experience recurrent urinary tract infections are at increased risk of graft failure and death.

High Rates of Infective Endocarditis Found Among ESRD Patients

High Rates of Infective Endocarditis Found Among ESRD Patients

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Hemodialysis patients had higher rates of infective endocarditis than peritoneal dialysis and kidney transplant patients.

Health Beliefs About Salt Intake Low Among Dialysis Patients

Health Beliefs About Salt Intake Low Among Dialysis Patients

Score for subscale of perceived seriousness for no reduction of salt intake higher in transplant patients.

High Phosphorus Ups Risk of Kidney Transplant Failure, Death

High Phosphorus Ups Risk of Kidney Transplant Failure, Death

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Each 1-mg/dL increase in serum phosphorus among kidney transplant recipients is associated with 36% and 21% increased risk in graft failure and death, respectively.

Kidneys From Octogenarian Donors Show Similar Survival

Kidneys From Octogenarian Donors Show Similar Survival

Biopsy-guided allocation of kidneys from octogenarian donors permits further expansion of the donor-organ pool.

Allograft Quality Not the Sole Reason for Turning Down Kidney

Allograft Quality Not the Sole Reason for Turning Down Kidney

There was a correlation for later acceptance in the match-run with delayed graft function, but not with all-cause graft failure.

IgG-Degrading Enzyme Desensitizes, Permits HLA-Incompatible Transplant

IgG-Degrading Enzyme Desensitizes, Permits HLA-Incompatible Transplant

IdeS reduced or eliminated donor-specific antibodies and permitted HLA-incompatible transplantation.

Melanoma Risk Higher in Kidney Transplant Recipients

Melanoma Risk Higher in Kidney Transplant Recipients

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Risk factors include older age, white race, and receiving a kidney from a living donor.

Worse Outcomes for HIV Kidney Recipients on Protease Inhibitor ART

Worse Outcomes for HIV Kidney Recipients on Protease Inhibitor ART

Increased risk of allograft loss, death for HIV-positive patients receiving protease inhibitor ART.

Viable Donor Kidneys May Be Discarded Based on Biopsy

Viable Donor Kidneys May Be Discarded Based on Biopsy

Most lower-quality kidneys also remained viable for nearly as long as the best kidneys, with 73.2% still working 5 years after transplant.

New UNOS Kidney Allocation System Narrowed Racial Gaps in Transplant

New UNOS Kidney Allocation System Narrowed Racial Gaps in Transplant

The researchers observed a narrowing of disparities in the average monthly transplantation rates with implementation of the new system.

Surgery More Effective for Post-Transplant Hyperparathyroidism

Surgery More Effective for Post-Transplant Hyperparathyroidism

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Up to half of transplant patients might experience tertiary hyperparathyroidism.

Transplanting Diabetic Kidneys Better Than Remaining on Waitlist

Transplanting Diabetic Kidneys Better Than Remaining on Waitlist

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Overall, recipients of diabetic donor kidneys had a 9% lower chance of dying compared with remaining on the waitlist.

Few Organ Transplant Recipients Have Important Cancer Screenings

Few Organ Transplant Recipients Have Important Cancer Screenings

During the observation period, the researchers found that 77.5%, 69.8%, and 91.4% of SOTRs were not up-to-date for colorectal, cervical, and breast cancer screening tests, respectively.

HCV-Infected Kidneys Transplanted to Uninfected Recipients

HCV-Infected Kidneys Transplanted to Uninfected Recipients

Early data from the study revealed this treatment effectively cleared hepatitis C from all of the patients.

PCSK9 Linked to New-Onset Diabetes After Kidney Transplantation

PCSK9 Linked to New-Onset Diabetes After Kidney Transplantation

NODAT occurred more frequently in the upper PCSK9 tertile vs the lowest two PCSK9 tertiles.

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