Transplantation

Skin Cancer After Organ Transplant Declining

Skin Cancer After Organ Transplant Declining

Standardized incidence ratio peaked in patients who underwent transplantation in 1983-1987 period.

Melanoma Staging System Updated

Melanoma Staging System Updated

Key changes include new N category descriptors, more stage III subgroups, new M1D designation.

Study Identifies Possible Way to Reduce Kidney Discard Rate

Study Identifies Possible Way to Reduce Kidney Discard Rate

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Limiting cold ischemia times could increase the use of renal allografts donated from patients after death from cardiovascular causes, researchers say.

Recurrent UTIs Worsen Kidney Transplant Outcomes

Recurrent UTIs Worsen Kidney Transplant Outcomes

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Kidney transplant recipients who experience recurrent urinary tract infections are at increased risk of graft failure and death.

High Rates of Infective Endocarditis Found Among ESRD Patients

High Rates of Infective Endocarditis Found Among ESRD Patients

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Hemodialysis patients had higher rates of infective endocarditis than peritoneal dialysis and kidney transplant patients.

Health Beliefs About Salt Intake Low Among Dialysis Patients

Health Beliefs About Salt Intake Low Among Dialysis Patients

Score for subscale of perceived seriousness for no reduction of salt intake higher in transplant patients.

High Phosphorus Ups Risk of Kidney Transplant Failure, Death

High Phosphorus Ups Risk of Kidney Transplant Failure, Death

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Each 1-mg/dL increase in serum phosphorus among kidney transplant recipients is associated with 36% and 21% increased risk in graft failure and death, respectively.

Kidneys From Octogenarian Donors Show Similar Survival

Kidneys From Octogenarian Donors Show Similar Survival

Biopsy-guided allocation of kidneys from octogenarian donors permits further expansion of the donor-organ pool.

Allograft Quality Not the Sole Reason for Turning Down Kidney

Allograft Quality Not the Sole Reason for Turning Down Kidney

There was a correlation for later acceptance in the match-run with delayed graft function, but not with all-cause graft failure.

IgG-Degrading Enzyme Desensitizes, Permits HLA-Incompatible Transplant

IgG-Degrading Enzyme Desensitizes, Permits HLA-Incompatible Transplant

IdeS reduced or eliminated donor-specific antibodies and permitted HLA-incompatible transplantation.

Melanoma Risk Higher in Kidney Transplant Recipients

Melanoma Risk Higher in Kidney Transplant Recipients

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Risk factors include older age, white race, and receiving a kidney from a living donor.

Worse Outcomes for HIV Kidney Recipients on Protease Inhibitor ART

Worse Outcomes for HIV Kidney Recipients on Protease Inhibitor ART

Increased risk of allograft loss, death for HIV-positive patients receiving protease inhibitor ART.

Viable Donor Kidneys May Be Discarded Based on Biopsy

Viable Donor Kidneys May Be Discarded Based on Biopsy

Most lower-quality kidneys also remained viable for nearly as long as the best kidneys, with 73.2% still working 5 years after transplant.

New UNOS Kidney Allocation System Narrowed Racial Gaps in Transplant

New UNOS Kidney Allocation System Narrowed Racial Gaps in Transplant

The researchers observed a narrowing of disparities in the average monthly transplantation rates with implementation of the new system.

Surgery More Effective for Post-Transplant Hyperparathyroidism

Surgery More Effective for Post-Transplant Hyperparathyroidism

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Up to half of transplant patients might experience tertiary hyperparathyroidism.

Transplanting Diabetic Kidneys Better Than Remaining on Waitlist

Transplanting Diabetic Kidneys Better Than Remaining on Waitlist

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Overall, recipients of diabetic donor kidneys had a 9% lower chance of dying compared with remaining on the waitlist.

Few Organ Transplant Recipients Have Important Cancer Screenings

Few Organ Transplant Recipients Have Important Cancer Screenings

During the observation period, the researchers found that 77.5%, 69.8%, and 91.4% of SOTRs were not up-to-date for colorectal, cervical, and breast cancer screening tests, respectively.

HCV-Infected Kidneys Transplanted to Uninfected Recipients

HCV-Infected Kidneys Transplanted to Uninfected Recipients

Early data from the study revealed this treatment effectively cleared hepatitis C from all of the patients.

PCSK9 Linked to New-Onset Diabetes After Kidney Transplantation

PCSK9 Linked to New-Onset Diabetes After Kidney Transplantation

NODAT occurred more frequently in the upper PCSK9 tertile vs the lowest two PCSK9 tertiles.

Low Muscle Mass Predicts Mortality in Obese Transplant Recipients

Low Muscle Mass Predicts Mortality in Obese Transplant Recipients

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In a study, obese transplant recipients with low muscle mass had an increased risk of death but not graft loss.

NODAT Risk Similar After Switching From CNIs to Everolimus

NODAT Risk Similar After Switching From CNIs to Everolimus

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The incidence of NODAT was 33.8% among patients who switched to everolimus and 36.4% among those who stayed on calcineurin inhibitors.

Post-Transplant Infections, Cancer Do Not Up Mortality

Post-Transplant Infections, Cancer Do Not Up Mortality

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Opportunistic viral and fungal infections or malignancies develop in 34% of kidney transplant recipients, but these complications do not affect patient or graft survival.

Antibiotic Combo Found to Reduce Post-Transplant UTI Rate

Antibiotic Combo Found to Reduce Post-Transplant UTI Rate

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Post-transplant UTI rates were lower when cephalexin was added to SMX-TMP than when SMX-TMP was used alone (7.5% vs 25.8%), study finds.

Diabetes Increases Post-Transplant Mortality Risk

Diabetes Increases Post-Transplant Mortality Risk

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In a study, diabetes in both the donor and recipient was associated with triple the risk of death at 5 years post-transplant compared with the absence of diabetes in both the donor and recipient.

Opioid Use Linked to Worse Outcomes in Kidney Transplant Patients

Opioid Use Linked to Worse Outcomes in Kidney Transplant Patients

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Highest level of opioid use in the year prior to transplantation was associated with a 45% and 28% increased risk of death and graft loss, respectively.

Bacteremia Worsens Kidney Transplant Outcomes

Bacteremia Worsens Kidney Transplant Outcomes

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Kidney transplant recipients who experienced an episode of bacteremia had double the risks of graft failure and death.

CCI May Predict Outcomes Among Older Kidney Recipients

CCI May Predict Outcomes Among Older Kidney Recipients

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Older patients with a Charlson Comorbidity Index score below 5 had a higher 3-year survival rate than those with a score of 5 or higher (90% vs 76%).

Accepting High-Risk Kidneys Is Better Than Waiting

Accepting High-Risk Kidneys Is Better Than Waiting

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High-KDPI kidneys can improve the likelihood of a functioning graft compared with waiting for a superior kidney.

VTE Linked to Higher Death, Graft Loss Risk in Transplant Recipients

VTE Linked to Higher Death, Graft Loss Risk in Transplant Recipients

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Venous thromboembolism is associated with a 4.1-fold increased risk of death and a 2.3-fold increased risk of death-censored graft loss among kidney transplant recipients.

Risk Factors for Contrast-Induced AKI in Transplant Patients ID'd

Risk Factors for Contrast-Induced AKI in Transplant Patients ID'd

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Risk factors include impaired renal function and inadequate hydration prior to contrast exposure.

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