Transplantation

Kidney Transplantation Followed by Drop in Sclerostin Levels

Kidney Transplantation Followed by Drop in Sclerostin Levels

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Improved renal function may contribute to the decline in a glycoprotein that inhibits bone formation.

Kidney Failure From Polycystic Disease Linked to Better Outcomes

Kidney Failure From Polycystic Disease Linked to Better Outcomes

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Patients are more likely to receive a kidney transplant and less likely to die than patients with end-stage renal disease from other causes.

Gender Disparity in Desire for Living Kidney Transplant

Gender Disparity in Desire for Living Kidney Transplant

Black female hemodialysis patients less likely to want living transplant; more likely to receive offer.

Survival Benefit of Expanded Criteria Kidneys Probed

Survival Benefit of Expanded Criteria Kidneys Probed

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For some highly sensitized patients, expanded criteria donor kidneys do not confer a survival edge over standard criteria donor kidneys.

Circulatory Death, Brain-Dead Donor Kidneys Offer Equivalent Outcomes

Circulatory Death, Brain-Dead Donor Kidneys Offer Equivalent Outcomes

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Kidney transplanted from brain-dead donors or those who died from circulatory causes are associated with similar patient and graft survival.

Transplant Induction Protocols Offer Similar Patient, Graft Survival

Transplant Induction Protocols Offer Similar Patient, Graft Survival

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Study compared single-dose alemtuzumab and multiple-dose rabbit anti-thymocyte globulin.

Post-Transplant UTI Prophylaxis Protocol Addresses Sulfa Allergy

Post-Transplant UTI Prophylaxis Protocol Addresses Sulfa Allergy

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Using cephalexin instead of trimethoprim-sulfamethoxazole may decrease UTI incidence and cost of care.

Risk Model Predicts Transplant Patient Readmission Risk

Risk Model Predicts Transplant Patient Readmission Risk

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Less than a high school education and delayed graft function are among the factors that increase the risk of readmission within 30 days.

Prior Cancer Ups Death Risk After Kidney Transplantation

Prior Cancer Ups Death Risk After Kidney Transplantation

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A pre-transplant history of malignancy increases the 10-year post-transplant mortality risk by 22%.

Older Age Predicts Renal Function Decline in Living Donors

Older Age Predicts Renal Function Decline in Living Donors

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Mean estimated glomerular filtration rate decreases by 0.57 mL/min/1.73 m2 annually with each 1-year increase in age at donation.

Living Kidney Donors Are At Higher Gout Risk

Living Kidney Donors Are At Higher Gout Risk

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In a study, donors were 60% more likely to be diagnosed with gout than matched healthy controls.

Kidney Donors Face Higher ESRD Risk

Kidney Donors Face Higher ESRD Risk

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They also are at elevated risk of cardiovascular and all-cause mortality, study finds.

Kidney Donation Safe for Older Donors

Kidney Donation Safe for Older Donors

No differences found in mortality, CVD between donors, nondonors older than 55.

Nephron Sparing Surgery Okay for Tumors in Transplanted Kidneys

Nephron Sparing Surgery Okay for Tumors in Transplanted Kidneys

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At last follow-up, 41 of 43 patients who underwent partial nephrectomy did not require dialysis.

Obesity Raises Risk of Delayed Renal Allograft Function

Obesity Raises Risk of Delayed Renal Allograft Function

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Delayed graft function is 41% more likely in obese than non-obese kidney transplant recipients.

The Need for a Kidney Research Prize: Interview with Sharon Moe, MD

The Need for a Kidney Research Prize: Interview with Sharon Moe, MD

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Dr. Moe spoke about the importance of nephrology research and how a prize competition can facilitate the process.

Fracture Risk Varies by Renal Replacement Therapy

Fracture Risk Varies by Renal Replacement Therapy

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Hemodialysis patients are at higher risk than peritoneal dialysis and renal transplant recipients.

Acute Rejection Linked to Ketoconazole

Acute Rejection Linked to Ketoconazole

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When administered concomitantly with tacrolimus in kidney transplant patients, it hiked the risk of acute rejection by more than 2-fold.

Transplant Outcomes Better in IgA Nephropathy Patients

Transplant Outcomes Better in IgA Nephropathy Patients

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Their unadjusted 5-year death-censored graft survival and patient survival rates are higher compared with other recipients.

Kidney Transplants Less Likely in Overweight, Obese Women

Kidney Transplants Less Likely in Overweight, Obese Women

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The odds of receiving a kidney decreased with increasing body mass index.

Sirolimus Reduces Post-Transplant HIV Levels

Sirolimus Reduces Post-Transplant HIV Levels

Lower post-transplant HIV DNA levels associated with sirolimus use.

Kidney Remaining After Donor Nephrectomy Increases in Size

Kidney Remaining After Donor Nephrectomy Increases in Size

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Increment in renal parenchymal volume occurs within days after a kidney is removed from a living donor.

Post-Transplant Diabetes Risk Tied to BMI

Post-Transplant Diabetes Risk Tied to BMI

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The risk of new-onset diabetes after a kidney transplant increases along with pretransplant body mass index.

Post-Transplant Hip Fracture Rate Declining

Post-Transplant Hip Fracture Rate Declining

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Hip fractures remain an important complication following kidney transplantation, but incidence has decreased substantially.

Do you have any patients who acquired a kidney transplant abroad?

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More than 90,000 kidney transplant candidates are on transplant waiting lists in the U.S.

Ribavirin May Treat HEV Infection in Transplant Recipients

Ribavirin May Treat HEV Infection in Transplant Recipients

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Serum hepatitis E virus levels were undetectable in 78% of patients at least 6 months after stopping treatment.

Urine Test IDs Cause of Post-Transplant Kidney Problems

Urine Test IDs Cause of Post-Transplant Kidney Problems

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By measuring urinary mRNA, a novel assay may enable clinicians to differentiate common causes of elevated creatinine.

Biopsy-Based Discard of Donor Kidneys May Be Misguided

Biopsy-Based Discard of Donor Kidneys May Be Misguided

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Biopsies are of little value in determining overall risk of delayed organ function or even premature organ failure, researcher says.

Immunosuppression-Free Transplant: Interview with Suzanne Ildstad, MD

Immunosuppression-Free Transplant: Interview with Suzanne Ildstad, MD

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Immunologic mismatch may no longer be a barrier between living kidney donors and recipients.

Kidney Donors at Slightly Higher ESRD Risk

Kidney Donors at Slightly Higher ESRD Risk

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By age 80 years, the estimated lifetime risk of ESRD was 90 per 10,000 live donors compared with 326 per 10,000 in the general population.

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