Transplantation

Belatacept Improves Kidney Transplant Outcomes

Belatacept Improves Kidney Transplant Outcomes

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At 7 years after kidney transplantation, belatacept recipients had lower risks of death and graft loss than those treated with cyclosporine.

Risk of Cancer Death Up for Organ Recipients

Risk of Cancer Death Up for Organ Recipients

Cancer second leading cause of death in solid-organ transplant recipients.

Any Renal Function Decline in Living Kidney Donors a Cardiac Risk

Any Renal Function Decline in Living Kidney Donors a Cardiac Risk

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Increased left ventricular mass found in donors with even mild decreases in renal function.

PSA Screening May Harm ESRD Patients Awaiting Transplant

PSA Screening May Harm ESRD Patients Awaiting Transplant

Screening not linked to improved patient survival after transplant; may delay time to listing, transplant.

Racial/Ethnic Disparities in Home Dialysis Outcomes Identified

Racial/Ethnic Disparities in Home Dialysis Outcomes Identified

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Blacks undergoing PD or home HD and Hispanics undergoing PD are less likely than their white counterparts to receive a kidney transplant.

Some Discarded Higher-Risk Kidneys May Be Transplantable

Some Discarded Higher-Risk Kidneys May Be Transplantable

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Just over half of kidneys from deceased ECD/DCD donors are not used, study finds.

ACE Inhibitors May Not Benefit Transplant Patients With Proteinuria

ACE Inhibitors May Not Benefit Transplant Patients With Proteinuria

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In a study, ramipril was not significantly better than placebo in preserving renal function in kidney transplant recipients.

ESRD and Treatments May Raise Cancer Risk

ESRD and Treatments May Raise Cancer Risk

Dialysis, organ transplant may increase odds for certain types of cancer.

Hepatitis, CMV More Common in Commercial Transplants

Hepatitis, CMV More Common in Commercial Transplants

Overall one- and ten-year survival rates of the transplanted organs in commercial recipients compared with controls were 91% and 22% vs. 98% and 44%.

Peritoneal Dialysis Patients May Have Better Post-Transplant Survival

Peritoneal Dialysis Patients May Have Better Post-Transplant Survival

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Meta-analysis suggests a 9% decreased 5-year mortality risk associated with pre-transplant peritoneal dialysis versus hemodialysis.

Iron Deficiency Ups Mortality in Renal Transplant Recipients

Iron Deficiency Ups Mortality in Renal Transplant Recipients

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The association is independent of anemia, according to researchers.

Increasing Antibiotic Resistance Plagues Surgery, Chemo

Increasing Antibiotic Resistance Plagues Surgery, Chemo

10% rise in antibiotic resistance would lead to 2,100 more deaths, 40,000 more infections yearly.

Safety-Net Hospitals Have Higher Costs, Worse Outcomes

Safety-Net Hospitals Have Higher Costs, Worse Outcomes

Found to have higher mortality, readmission, surgical costs after controlling for patient factors.

LVH Regression Improves Outcomes in Renal Transplant Recipients

LVH Regression Improves Outcomes in Renal Transplant Recipients

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Reduction in left ventricular hypertrophy predicts a decreased long-term risk of death and cardiovascular events, study finds.

Low Post-Transplant Magnesium Ups Risk of New-Onset Diabetes

Low Post-Transplant Magnesium Ups Risk of New-Onset Diabetes

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Hypomagnesemia after a kidney transplant is associated with a 58% increased risk of new-onset diabetes.

BK Virus Screening in Transplant Patients May Be Suboptimal

BK Virus Screening in Transplant Patients May Be Suboptimal

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Researchers find an association between late-onset BK virus nephropathy and less adherence to screening guidelines.

Infected Kidney Donors Raise Delayed Graft Function Risk

Infected Kidney Donors Raise Delayed Graft Function Risk

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Kidneys from blood culture positive donors are not associated with graft and patient survival, however.

Reduced-Dose Tacrolimus, Everolimus Cut CMV Infection

Reduced-Dose Tacrolimus, Everolimus Cut CMV Infection

Findings in de novo kidney recipients receiving no pharmacologic CMV prophylaxis.

Surgeons Perform Well Despite Late Night and Early Morning Operations

Surgeons Perform Well Despite Late Night and Early Morning Operations

Review indicates that doctors who operate the night before another surgery do well.

Greater Melanoma Risks Found Among Transplant Recipients

Greater Melanoma Risks Found Among Transplant Recipients

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They have double the risk of invasive melanoma and triple the risk of dying from it.

Music Aids Patient Recovery from Surgery

Music Aids Patient Recovery from Surgery

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Patients who listened to music had less pain, anxiety, and analgesia use after their operations, compared with patients receiving routine care or non-drug interventions.

Few Referrals for Transplant Evaluation Among Dialysis Patients

Few Referrals for Transplant Evaluation Among Dialysis Patients

Findings among end-stage renal disease patients initiating dialysis in Georgia.

Predictors of ECD Kidney Transplant Long-Term Outcomes Identified

Predictors of ECD Kidney Transplant Long-Term Outcomes Identified

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The main independent determinants are circulating donor-specific anti-HLA antibody and cold ischemia time.

Organ Donation Rates Mostly Unaffected by State Policies

Organ Donation Rates Mostly Unaffected by State Policies

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From 1988 to 2010, establishment of organ donation registries, tax incentives, and paid leave have had no significant effect.

Kidney Transplant Outcomes Better If Donors Are Kept in Hypothermia

Kidney Transplant Outcomes Better If Donors Are Kept in Hypothermia

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Risk of delayed graft function is reduced when donors are maintained at a temperature of 93.2° to 95° F prior to kidney harvesting after death.

BMI Doesn't Affect Kidney Transplant Survival

BMI Doesn't Affect Kidney Transplant Survival

No difference between defined BMI bands in patient or graft survival for transplanted patients.

Post-Transplant UTI Risk Factors Identified

Post-Transplant UTI Risk Factors Identified

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Female kidney recipients have a nearly 7-fold higher risk of UTI than their male counterparts.

Steroid Withdrawal May Not Prevent Post-transplant Diabetes

Steroid Withdrawal May Not Prevent Post-transplant Diabetes

Limited effect among adult patients during 5 years following kidney transplantation.

Laparoscopically Harvesting Right Kidneys from Living Donors Safe

Laparoscopically Harvesting Right Kidneys from Living Donors Safe

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Donor and recipient outcomes are similar to those associated with laparoscopic removal of left donor kidneys.

High n-3 PUFA Intake Improves Survival After Kidney Transplantation

High n-3 PUFA Intake Improves Survival After Kidney Transplantation

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Highest versus lowest intake associated with a 67% and 88% lower risk of all-cause and cardiovascular mortality, respectively.

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