Transplantation

African-American Kidneys May Worsen Transplant Outcomes

February 01, 2012

Recipients of kidneys from African Americans (AA) are at increased risk of all-cause and cardiovascular mortality compared with patients who receive kidneys from non-AA donors.
 

Correcting Anemia Can Protect Renal Allografts

January 31, 2012

Targeting hemoglobin (Hb) values of 13 g/dL or higher reduces progression of chronic allograft nephropathy in kidney-transplant recipients, a prospective study suggests.
 

Risk Factors for Transplant-Related Urinary Complications Characterized

January 26, 2012

MIAMI BEACH, Fla.—A review of 635 kidney transplants performed at the University of Florida, Gainesville, has confirmed that transplanted kidneys with more than one renal artery put recipients at increased risk for urinary complications.
 

Online Tools Increase Efficiency, Speed of Kidney Donor Screening

January 25, 2012

MIAMI BEACH, Fla.—Using web-based preliminary screening of potential kidney donors has resulted in a flood of applications at two U.S. transplant centers.
 

Stents May Benefit Renal Transplant Patients

January 24, 2012

Ureteral stents in recipients of deceased donor organs lower the risk of ureteral complications.
 

Deceased Donor Transplantation Rates Declining

January 13, 2012

Dialysis patients waiting for a deceased donor kidney transplant face a declining likelihood of receiving one, according to a recent study.
 

Correcting Anemia Reduces Odds of Renal Transplant Failure

December 29, 2011

Complete correction of anemia (hemoglobin, 13 g/dL or higher) in kidney transplant recipients slows progression to chronic allograft nephropathy, a study found.
 

Transplant Outcomes Unaffected by High-Dose Erythropoietin

November 30, 2011

High-dose erythropoietin has no significant effect on short- or long-term graft function in renal transplant patients who had chronic kidney disease (CKD) after receiving a deceased donor organ, according to a new study.
 

Kidney Transplants Fail to Stop Coronary Artery Calcification

November 02, 2011

Renal transplantation does not stop or reverse coronary artery calcification (CAC), according to researchers.
 

Regional Anesthesia Benefits Kidney Recipients

November 01, 2011

CHICAGO—Regional anesthesia significantly reduces nausea and opioid use in the first two days after kidney transplantation, new findings suggest.
 

Most Anonymous Kidney Donors Altruistic, Studies Show

October 28, 2011

VANCOUVER, B.C.—Individuals who wish to donate a kidney anonymously are motivated by altruism rather than psychopathology, according to new studies.
 

Kidney Graft Loss Due to BK Virus Need Not Prevent Retransplantation

October 26, 2011

BOSTON—Retransplantation after kidney graft loss due to BK virus nephropathy appears to be safe and feasible. However, replacing alemtuzumab with basiliximab may be necessary to achieve optimal outcomes in retransplanted patients, according to data presented at the Infectious Diseases Society of America annual meeting.
 

Acute Transplant Rejection Rate Lower with Alemtuzumab

October 25, 2011

BOSTON—Alemtuzumab use is associated with a lower incidence of acute rejection and infection compared to rabbit anti-thymocyte globulin (rATG) induction in kidney and pancreas transplant recipients, regardless of age or ethnicity, according to a new study presented at the Infectious Diseases Society of America annual meeting.
 

Lower Albumin Predicts Worse Post-Transplant Outcomes

September 23, 2011

Lower pretransplant serum albumin levels are associated with worse outcomes following renal transplantation, according to researchers.
 

Policy Change Boosts Minority Kidney Transplants

August 05, 2011

The overall number of deceased-donor kidney transplants rose 40% for minorities and 8% for non-Hispanic whites from the six years before to the six years after the U.S. kidney allocation system eliminated the allocation priority for matching of HLA-B antigens between candidates and potential deceased donors.
 

Squirrels May Offer Clues to Preserving Organs

July 26, 2011

VANCOUVER, B.C.—The 13-lined hibernating ground squirrel may provide clues to keeping organs cold and well preserved for prolonged periods, according to research presented at the 2011 World Congress of Nephrology.
 

RAS Blockade Improves Transplant Patient Survival

July 19, 2011

Medications that block the renin-angiotensin system (RAS) may improve survival among renal transplant recipients, according to researchers.
 

Donor Genes, Not Race, Affect Graft Survival

July 19, 2011

Transplanted kidneys from deceased African-American donors fail more rapidly if they harbor two risk variants of the apolipoprotein L1 (APOL1) gene as opposed to one or no risk variant.
 

Medical Abnormalities Need Not Exclude Middle-Aged Kidney Donors

June 30, 2011

VANCOUVER, B.C.—Middle-aged individuals with isolated medical abnormalities are often acceptable as kidney donors, a researcher said.
 

Study: PD Patients Receive Kidney Transplants Sooner

June 28, 2011

PRAGUE—End-stage renal disease patients who start on peritoneal dialysis (PD) rather than hemodialysis (HD) spend less time on a renal transplant waiting list before getting a kidney, new findings suggest.
 

Post-Transplantation Anemia Risk Factors Identified

June 28, 2011

PRAGUE—Renal transplant recipients who have anemia three months after receiving a kidney are more likely to have anemia more than six months post-transplant, according to researchers.
 

Anti-Rejection Drug Cleared for Use in Kidney Transplant Patients

June 16, 2011

The FDA has approved belatacept (Nulojix) for preventing acute rejection of transplanted kidneys in adults.
 

Why I Donated a Kidney Anonymously

May 23, 2011

After extensive medical and psychological testing over many months, a Canadian citizen parted with one of her kidneys to help somebody she did not know. Click on the title to read a detailed account of her experience.
 

DGF Requiring More than One-Time Dialysis Raises Death Risk

May 04, 2011

PHILADELPHIA—Delayed graft function (DGF) requiring more than one-time dialysis is associated with increased death risk, according to findings presented at the 2011 American Transplant Congress.
 

Urine Biomarkers On First Day After Transplant Predict One-Year Outcomes

May 04, 2011

PHILADELPHIA—Higher urinary levels of two biomarkers on the first day following renal transplantation can predict poor graft function at one year, researchers reported at the 2011 American Transplant Congress.
 

Metabolic Syndrome Common After Renal Transplantation

May 03, 2011

PHILADELPHIA—Metabolic syndrome (MS) is present in 35%-40% of renal transplant recipients in the first five years post-transplant, new findings suggest.
 

Tx Patients Fail to Meet SBP Targets

May 03, 2011

PHILADELPHIA—Most renal transplant recipients (RTRs) fail to achieve recommended systolic blood pressure (SBP) levels despite being prescribed antihypertensive medications. Consequently, they may be at increased risk for cardiovascular disease (CVD), a study found.
 

Donor Kidney Weight Affects Transplant Outcomes

May 02, 2011

PHILADELPHIA—Renal transplants recipients who receive a heavier kidney relative to their body weight have better long-term graft survival and early graft function, researchers reported.
 

Obese Donors Not At Higher Renal Risk

May 02, 2011

PHILADELPHIA—Obese kidney donors are not at elevated risk for renal dysfunction long term, but they may experience an increase in risk factors for cardiovascular disease (CVD), according to researchers.
 

Flu Vaccine Safe, Lowers Death Risk Post Tx

May 02, 2011

Influenza vaccination in the first year after renal transplantation is safe and is associated with a lower risk of subsequent allograft loss and death, a study found.
 

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