Biopsy-guided allocation of kidneys from octogenarian donors permits further expansion of the donor-organ pool.
There was a correlation for later acceptance in the match-run with delayed graft function, but not with all-cause graft failure.
IdeS reduced or eliminated donor-specific antibodies and permitted HLA-incompatible transplantation.
Risk factors include older age, white race, and receiving a kidney from a living donor.
Increased risk of allograft loss, death for HIV-positive patients receiving protease inhibitor ART.
Most lower-quality kidneys also remained viable for nearly as long as the best kidneys, with 73.2% still working 5 years after transplant.
The researchers observed a narrowing of disparities in the average monthly transplantation rates with implementation of the new system.
Up to half of transplant patients might experience tertiary hyperparathyroidism.
Overall, recipients of diabetic donor kidneys had a 9% lower chance of dying compared with remaining on the waitlist.
During the observation period, the researchers found that 77.5%, 69.8%, and 91.4% of SOTRs were not up-to-date for colorectal, cervical, and breast cancer screening tests, respectively.
Early data from the study revealed this treatment effectively cleared hepatitis C from all of the patients.
NODAT occurred more frequently in the upper PCSK9 tertile vs the lowest two PCSK9 tertiles.
In a study, obese transplant recipients with low muscle mass had an increased risk of death but not graft loss.
The incidence of NODAT was 33.8% among patients who switched to everolimus and 36.4% among those who stayed on calcineurin inhibitors.
Opportunistic viral and fungal infections or malignancies develop in 34% of kidney transplant recipients, but these complications do not affect patient or graft survival.
Post-transplant UTI rates were lower when cephalexin was added to SMX-TMP than when SMX-TMP was used alone (7.5% vs 25.8%), study finds.
In a study, diabetes in both the donor and recipient was associated with triple the risk of death at 5 years post-transplant compared with the absence of diabetes in both the donor and recipient.
Highest level of opioid use in the year prior to transplantation was associated with a 45% and 28% increased risk of death and graft loss, respectively.
Kidney transplant recipients who experienced an episode of bacteremia had double the risks of graft failure and death.
Older patients with a Charlson Comorbidity Index score below 5 had a higher 3-year survival rate than those with a score of 5 or higher (90% vs 76%).
High-KDPI kidneys can improve the likelihood of a functioning graft compared with waiting for a superior kidney.
Venous thromboembolism is associated with a 4.1-fold increased risk of death and a 2.3-fold increased risk of death-censored graft loss among kidney transplant recipients.
Risk factors include impaired renal function and inadequate hydration prior to contrast exposure.
Angioplasty plus stenting is associated with less residual stenosis and a lower restenosis rate compared with angioplasty alone.
Researchers report that matching deceased kidney donors and kidney recipients by cytomegalovirus serostatus optimizes high- and low-risk profiles.
Five-year graft survival rates among recipients of kidneys from living donors increased from 76.6% in 1985-1894 to 85.4% in 2009-2015.
In a study of renal transplant patients who received ureteral stents, ciprofloxacin did not lower the incidence of UTI compared with SMX-TMP.
The adjusted 5-year risk of insulin use following donation is 5 times higher among obese vs normal weight donors.
Cinacalcet treatment may serve as a bridge to parathyroidectomy or as an alternative, researchers say.
Among 1734 childhood recipients, 289 developed cancer over a median follow-up of 13.4 years.
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- Acute Kidney Injury (AKI)
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