Transplantation

New UNOS Kidney Allocation System Narrowed Racial Gaps in Transplant

New UNOS Kidney Allocation System Narrowed Racial Gaps in Transplant

The researchers observed a narrowing of disparities in the average monthly transplantation rates with implementation of the new system.

Surgery More Effective for Post-Transplant Hyperparathyroidism

Surgery More Effective for Post-Transplant Hyperparathyroidism

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Up to half of transplant patients might experience tertiary hyperparathyroidism.

Transplanting Diabetic Kidneys Better Than Remaining on Waitlist

Transplanting Diabetic Kidneys Better Than Remaining on Waitlist

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Overall, recipients of diabetic donor kidneys had a 9% lower chance of dying compared with remaining on the waitlist.

Few Organ Transplant Recipients Have Important Cancer Screenings

Few Organ Transplant Recipients Have Important Cancer Screenings

During the observation period, the researchers found that 77.5%, 69.8%, and 91.4% of SOTRs were not up-to-date for colorectal, cervical, and breast cancer screening tests, respectively.

HCV-Infected Kidneys Transplanted to Uninfected Recipients

HCV-Infected Kidneys Transplanted to Uninfected Recipients

Early data from the study revealed this treatment effectively cleared hepatitis C from all of the patients.

PCSK9 Linked to New-Onset Diabetes After Kidney Transplantation

PCSK9 Linked to New-Onset Diabetes After Kidney Transplantation

NODAT occurred more frequently in the upper PCSK9 tertile vs the lowest two PCSK9 tertiles.

Low Muscle Mass Predicts Mortality in Obese Transplant Recipients

Low Muscle Mass Predicts Mortality in Obese Transplant Recipients

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In a study, obese transplant recipients with low muscle mass had an increased risk of death but not graft loss.

NODAT Risk Similar After Switching From CNIs to Everolimus

NODAT Risk Similar After Switching From CNIs to Everolimus

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The incidence of NODAT was 33.8% among patients who switched to everolimus and 36.4% among those who stayed on calcineurin inhibitors.

Post-Transplant Infections, Cancer Do Not Up Mortality

Post-Transplant Infections, Cancer Do Not Up Mortality

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Opportunistic viral and fungal infections or malignancies develop in 34% of kidney transplant recipients, but these complications do not affect patient or graft survival.

Antibiotic Combo Found to Reduce Post-Transplant UTI Rate

Antibiotic Combo Found to Reduce Post-Transplant UTI Rate

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Post-transplant UTI rates were lower when cephalexin was added to SMX-TMP than when SMX-TMP was used alone (7.5% vs 25.8%), study finds.

Diabetes Increases Post-Transplant Mortality Risk

Diabetes Increases Post-Transplant Mortality Risk

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In a study, diabetes in both the donor and recipient was associated with triple the risk of death at 5 years post-transplant compared with the absence of diabetes in both the donor and recipient.

Opioid Use Linked to Worse Outcomes in Kidney Transplant Patients

Opioid Use Linked to Worse Outcomes in Kidney Transplant Patients

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Highest level of opioid use in the year prior to transplantation was associated with a 45% and 28% increased risk of death and graft loss, respectively.

Bacteremia Worsens Kidney Transplant Outcomes

Bacteremia Worsens Kidney Transplant Outcomes

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Kidney transplant recipients who experienced an episode of bacteremia had double the risks of graft failure and death.

CCI May Predict Outcomes Among Older Kidney Recipients

CCI May Predict Outcomes Among Older Kidney Recipients

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Older patients with a Charlson Comorbidity Index score below 5 had a higher 3-year survival rate than those with a score of 5 or higher (90% vs 76%).

Accepting High-Risk Kidneys Is Better Than Waiting

Accepting High-Risk Kidneys Is Better Than Waiting

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High-KDPI kidneys can improve the likelihood of a functioning graft compared with waiting for a superior kidney.

VTE Linked to Higher Death, Graft Loss Risk in Transplant Recipients

VTE Linked to Higher Death, Graft Loss Risk in Transplant Recipients

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Venous thromboembolism is associated with a 4.1-fold increased risk of death and a 2.3-fold increased risk of death-censored graft loss among kidney transplant recipients.

Risk Factors for Contrast-Induced AKI in Transplant Patients ID'd

Risk Factors for Contrast-Induced AKI in Transplant Patients ID'd

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Risk factors include impaired renal function and inadequate hydration prior to contrast exposure.

Stenting May Improve Transplant Renal Artery Stenosis Outcomes

Stenting May Improve Transplant Renal Artery Stenosis Outcomes

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Angioplasty plus stenting is associated with less residual stenosis and a lower restenosis rate compared with angioplasty alone.

Kidney Donor-Recipient CMV Matching Is a Promising Strategy

Kidney Donor-Recipient CMV Matching Is a Promising Strategy

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Researchers report that matching deceased kidney donors and kidney recipients by cytomegalovirus serostatus optimizes high- and low-risk profiles.

Living Kidney Donor Graft Survival Improving

Living Kidney Donor Graft Survival Improving

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Five-year graft survival rates among recipients of kidneys from living donors increased from 76.6% in 1985-1894 to 85.4% in 2009-2015.

Obesity Ups Diabetes Risk Among Living Kidney Donors

Obesity Ups Diabetes Risk Among Living Kidney Donors

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The adjusted 5-year risk of insulin use following donation is 5 times higher among obese vs normal weight donors.

Cipro Not Better for UTI Prophylaxis After Transplant With Stent

Cipro Not Better for UTI Prophylaxis After Transplant With Stent

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In a study of renal transplant patients who received ureteral stents, ciprofloxacin did not lower the incidence of UTI compared with SMX-TMP.

Cinacalcet Appears to Ease Hyperparathyroidism in Transplant Patients

Cinacalcet Appears to Ease Hyperparathyroidism in Transplant Patients

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Cinacalcet treatment may serve as a bridge to parathyroidectomy or as an alternative, researchers say.

Higher Cancer Risk for Pediatric Kidney Recipients

Higher Cancer Risk for Pediatric Kidney Recipients

Among 1734 childhood recipients, 289 developed cancer over a median follow-up of 13.4 years.

Donor-Recipient Weight, Sex Mismatch Ups Graft Loss

Donor-Recipient Weight, Sex Mismatch Ups Graft Loss

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Graft failure risk was highest when a recipient of a kidney from a donor of the opposite sex was more than 66 pounds heavier than the donor.

Pre-transplant Anti-donor Antibodies Linked With Better Kidney Survival

Pre-transplant Anti-donor Antibodies Linked With Better Kidney Survival

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Study supports transplant of kidneys into sensitized patients.

High-Volume Hospitals Recover More Transplantable Organs Per Donor

High-Volume Hospitals Recover More Transplantable Organs Per Donor

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Hospitals that managed the most deceased donors were 1.5 times more likely to recover 4 or more transplantable organs than those that managed the least.

Kidney Transplant Recipients Often Hospitalized With Acute MI

Kidney Transplant Recipients Often Hospitalized With Acute MI

Acute ST-segment elevation myocardial infarction (STEMI) accounted for 29.3% of RTR admissions.

Record Number of Transplants in 2016 Reported

Record Number of Transplants in 2016 Reported

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From 2015 to 2016, the number of organ transplants rose from 30,969 to 33,595; the number of kidney transplants increased from 17,878 to 19,061.

Anemia Control Similar for Transplant Patients Re-entering Dialysis

Anemia Control Similar for Transplant Patients Re-entering Dialysis

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Investigators observed no difference in hemoglobin level between transplant recipients and non-transplant CKD patients starting hemodialysis.

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