Transplantation

Ledipasvir-Sofosbuvir OK for Transplant Recipients With Hepatitis C

Ledipasvir-Sofosbuvir OK for Transplant Recipients With Hepatitis C

The researchers found that all patients treated for 12 and 24 weeks achieved sustained virologic response at 12 weeks after therapy ended.

Coccidioidomycosis Ups Death Risk in Organ Recipients

Coccidioidomycosis Ups Death Risk in Organ Recipients

Organs from CI-positive donors were associated with higher mortality.

Kidney Transplantation Rejection Remains High With HIV

Kidney Transplantation Rejection Remains High With HIV

While antiretroviral therapy has allowed HIV patients to undergo kidney transplantation, allograft rejection remains high in this group.

Fewer Post-Transplant Fractures With Practice Changes

Fewer Post-Transplant Fractures With Practice Changes

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Fracture incidence within a year of transplant was 3 times lower among patients who had surgery from 2009 to 2011 vs 2004 to 2006.

Kidney Donors Possibly at Risk for Bone Loss

Kidney Donors Possibly at Risk for Bone Loss

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Bone turnover markers increased following unilateral nephrectomy.

Nonmelanoma Skin Cancer Risk Up in Organ Transplant Recipients

Nonmelanoma Skin Cancer Risk Up in Organ Transplant Recipients

All recipients should have full-body skin evaluations after transplant surgery, regardless of ethnicity.

Kidney Transplant Patients Benefit From Bisphosphonates

Kidney Transplant Patients Benefit From Bisphosphonates

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Therapy was associated with a significant improvement in bone mineral density at the lumbar spine and femoral neck.

Donor, Recipient Factors Influence Kidney Transplant Costs

Donor, Recipient Factors Influence Kidney Transplant Costs

Living kidney donor costs up with higher degree of allosensitization; also linked to obesity.

Cancer Screening Guidelines for Transplant Recipients Need Improvement

Cancer Screening Guidelines for Transplant Recipients Need Improvement

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Guidelines for kidney recipients differ on frequency of cancer screenings.

Post-Transplant Decrease in Kidney Graft Size Predicts Worse Outcomes

Post-Transplant Decrease in Kidney Graft Size Predicts Worse Outcomes

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Study reveals a significantly higher risk of a 50% or greater decline in eGFR and end-stage graft failure.

Hepatitis C in CKD: Challenges and Opportunities

Hepatitis C in CKD: Challenges and Opportunities

The availability of direct-acting antiviral drugs may enable eradication of hepatitis C virus and improve outcomes.

Fracture Risk Factors in Transplant Patients ID'd

Fracture Risk Factors in Transplant Patients ID'd

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Major fractures included the proximal humerus, forearm, hip, and clinical vertebral fractures.

Smoking Hikes Mortality Risk Among Dialysis Patients

Smoking Hikes Mortality Risk Among Dialysis Patients

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Study also links smoking with a decreased likelihood of receiving a kidney transplant.

Emetine May Treat Cytomegalovirus Infection

Emetine May Treat Cytomegalovirus Infection

Inhibition with http://www.renalandurologynews.com/transplantation/section/635/ occurs after virus entry but before DNA replication.

Deceased-Donor Age Affects Kidney Transplant Outcomes

Deceased-Donor Age Affects Kidney Transplant Outcomes

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Recipients of kidneys from individuals who donated the organs after cardiac death are more likely to experience graft loss and delayed graft function.

Subtotal Parathyroidectomy Safe, Effective, Study Finds

Subtotal Parathyroidectomy Safe, Effective, Study Finds

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Researchers highlighted the benefit of iPTH monitoring.

Worse Re-transplant Outcomes for HIV Positive Patients

Worse Re-transplant Outcomes for HIV Positive Patients

HIV retransplant recipients have increased risk of death and graft loss versus HIV re-KT patients

Bariatric Surgery May Increase Risk of Renal Allograft Loss

Bariatric Surgery May Increase Risk of Renal Allograft Loss

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Possible reasons include malabsorption of immunosuppressive drugs and deposition of oxalate crystals in transplanted kidneys.

Patient Non-Adherence Predicts Worse Kidney Transplant Outcomes

Patient Non-Adherence Predicts Worse Kidney Transplant Outcomes

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Rates of non-adherence to follow-up care and medication regimens also found to differ by race.

Prior Living Kidney Donors With ESRD May Not Get Timely Transplants

Prior Living Kidney Donors With ESRD May Not Get Timely Transplants

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Some donors spend years on dialysis before being placed on the kidney transplant waiting list.

Muscle Density Predicts Death Risk in Patients Waiting for a Kidney

Muscle Density Predicts Death Risk in Patients Waiting for a Kidney

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Each Hounsfield unit increase on CT is associated with a 7% decreased risk of death among waitlisted kidney transplant candidates.

Post-Kidney Transplant Mortality Linked to Pre-Existing Heart Disease

Post-Kidney Transplant Mortality Linked to Pre-Existing Heart Disease

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Coronary artery disease before transplantation increases death risk by 77%, study finds.

Long-Term Kidney Transplant Outcomes Linked to 30% eGFR Decline

Long-Term Kidney Transplant Outcomes Linked to 30% eGFR Decline

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An eGFR decline of at least 30% during the 6 to 24 months after kidney transplantation predicts a higher risk of graft loss.

Morbid Obesity Ups Viral Infection Risk After a Kidney Transplant

Morbid Obesity Ups Viral Infection Risk After a Kidney Transplant

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In a study, viral infections occurred in 52.4% of patients with a BMI of 35 kg/m2 or higher compared with 37.1% of those with a lower BMI.

Surgeons Perform First Penile Transplant in the US

Surgeons Perform First Penile Transplant in the US

The 15-hour surgery took place in early May.

Weekend Effect Observed for Donor Kidney Discard

Weekend Effect Observed for Donor Kidney Discard

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Deceased donor kidneys obtained on Friday or Saturday were 16% more likely to be discarded than transplanted, compared with organs gathered other days of the week.

Oral Nicotinamide Safe for Renal Transplant Recipients

Oral Nicotinamide Safe for Renal Transplant Recipients

Oral nicotinamide has been linked to nonsignificant reductions in new, non-melanoma skin cancers in renal transplant patients.

Weekend Transplant Outcomes Not Worse

Weekend Transplant Outcomes Not Worse

Nearly 28% of deceased-donor kidney transplants in the US were performed on the weekends.

Renal Transplant Patients At Higher Risk of Papillary RCC

Renal Transplant Patients At Higher Risk of Papillary RCC

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Only this histologic variant occurs at a significantly higher incidence in renal allograft recipients than the non-transplant population.

No Routine Antimicrobial Use for Post-Transplant Asymptomatic Bacteriuria

No Routine Antimicrobial Use for Post-Transplant Asymptomatic Bacteriuria

At 24 months follow up, no difference was found in primary outcomes in those treated for asymptomatic bacteriuria.

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