Even though rate of disease is on the rise, fewer patients are suffering organ failure or dying
Targeted pathogens include AIDS-causing HIV, hepatitis B and C, and the West Nile virus
The changes to kidney transplant rules are intended to make organ allocation more equitable.
Researchers identified a genetic glitch that promotes kidney scarring.
Living kidney donors who are in need of a transplant later in life experience shorter wait times and receive better quality kidneys.
Living kidney donors are more likely to be diagnosed with high blood pressure or preemclampsia once pregnant compared to non-donor.
An anticoagulant was found to preserve kidney function after transplantation.
Researchers may have found a predictor for focal segmental glomerulosclerosis (FSGS) in kidney transplant recipients.
More reimbursement and compensation opportunities should be available for living kidney donors.
This approach resulted in improved hypertension control in patients with autosomal dominant polycystic kidney disease, new study found.
The vast majority of kidney failure patients reported that they were doing fine on dialysis and did not see a need for a kidney transplant.
Researchers expect to start safety and performance testing of the Wearable Artificial Kidney (WAK) this autumn.
Ultrasound surveillance for renal tumors should be performed on native and graft kidneys from 3 years after transplantation.
Barriers to donation may explain why living donor kidney transplantation has been declining.
In adjusted analyses, female transplant recipients had a significantly increased risk of urologic cancer and men did not.
Graft survival was similar to that seen in concurrent single SCD kidney recipients
Improved renal function may contribute to the decline in a glycoprotein that inhibits bone formation.
Patients are more likely to receive a kidney transplant and less likely to die than patients with end-stage renal disease from other causes.
Black female hemodialysis patients less likely to want living transplant; more likely to receive offer.
For some highly sensitized patients, expanded criteria donor kidneys do not confer a survival edge over standard criteria donor kidneys.
Kidney transplanted from brain-dead donors or those who died from circulatory causes are associated with similar patient and graft survival.
Study compared single-dose alemtuzumab and multiple-dose rabbit anti-thymocyte globulin.
Using cephalexin instead of trimethoprim-sulfamethoxazole may decrease UTI incidence and cost of care.
Less than a high school education and delayed graft function are among the factors that increase the risk of readmission within 30 days.
A pre-transplant history of malignancy increases the 10-year post-transplant mortality risk by 22%.
Mean estimated glomerular filtration rate decreases by 0.57 mL/min/1.73 m2 annually with each 1-year increase in age at donation.
In a study, donors were 60% more likely to be diagnosed with gout than matched healthy controls.
They also are at elevated risk of cardiovascular and all-cause mortality, study finds.
No differences found in mortality, CVD between donors, nondonors older than 55.
At last follow-up, 41 of 43 patients who underwent partial nephrectomy did not require dialysis.
Delayed graft function is 41% more likely in obese than non-obese kidney transplant recipients.
Dr. Moe spoke about the importance of nephrology research and how a prize competition can facilitate the process.
Hemodialysis patients are at higher risk than peritoneal dialysis and renal transplant recipients.
When administered concomitantly with tacrolimus in kidney transplant patients, it hiked the risk of acute rejection by more than 2-fold.
Their unadjusted 5-year death-censored graft survival and patient survival rates are higher compared with other recipients.
The odds of receiving a kidney decreased with increasing body mass index.
Lower post-transplant HIV DNA levels associated with sirolimus use.
Increment in renal parenchymal volume occurs within days after a kidney is removed from a living donor.
The risk of new-onset diabetes after a kidney transplant increases along with pretransplant body mass index.
Hip fractures remain an important complication following kidney transplantation, but incidence has decreased substantially.
More than 90,000 kidney transplant candidates are on transplant waiting lists in the U.S.
Serum hepatitis E virus levels were undetectable in 78% of patients at least 6 months after stopping treatment.
By measuring urinary mRNA, a novel assay may enable clinicians to differentiate common causes of elevated creatinine.
Biopsies are of little value in determining overall risk of delayed organ function or even premature organ failure, researcher says.
Immunologic mismatch may no longer be a barrier between living kidney donors and recipients.
By age 80 years, the estimated lifetime risk of ESRD was 90 per 10,000 live donors compared with 326 per 10,000 in the general population.
Sitagliptin was well tolerated and it significantly increased insulin secretion and reduced glucose levels.
A new study is suggesting there is substantial geographic variation in deceased donor kidney waiting times.
Levels above 500 ng/mL predicted higher incidence rates of infections overall as well as bacterial and bloodstream infections.
Renal tissue could one day be created that would be functional as well as completely immunocompatible.
HIV-1 was found in podocytes or tubular cells of renal allografts in recipients who did not have detectable plasma levels of the virus.
As a venue for presenting important research on kidney disease to the world, Kidney Week never disappoints.
A new study from University of Illinois researchers suggests that it may be possible to increase kidney donation through a multiple-message campaign.
Children who undergo solid organ transplantation may have a high risk of developing kidney disease, according to a new national study.
Increasing age and receipt of a deceased-donor kidney were among risk factors for death from infection.
Complications and hospital lengths of stay after kidney donation declined from 10.1% and a mean 3.7 days, respectively.
In a study, only 8% of readmissions within 30 days of discharge met preventability criteria.
A new study has looked at the health of kidney donors and turned up some rather interesting findings in terms of short-term health risks.
'Even 100 days out the risk is still high and it is still going higher,' researcher says.
Researchers evaluated sulfamethoxazole-trimethoprim single-strength twice-weekly in abdominal organ transplant patients.
Presence of complement-binding donor-specific antibodies increases risk of graft loss.
High risker of biopsy-proven acute rejection and death-censored graft failure observed in patients with a BMI of 35 kg/m2 or greater.
Even after five years on the drug, patients continue to have improved renal function compared with patients receiving cyclosporine A.
Cidofovir cleared cytomegalovirus that was resistant to ganciclovir.
Patients who receive their first kidney transplant at ages 14-16 years appear to be at increased risk for transplant failure.
Donors had a decrease in GFR and an increase in parathyroid hormone and uric acid six months after nephrectomy.
At one-year post-transplant, the risk of death was reduced by 66% or more in transplant recipients with a BMI below 40, but was reduced by only 48% in recipients with a BMI of 40 or higher
Severe fluid overload in patients with advanced CKD increases by threefold the likelihood of initiation of renal replacement therapy.
Robotic kidney transplants may significantly improve outcomes in obese patients.
Social media is playing a significant role in organ donation registration.
A study shows that with appropriate screening and selection, kidney transplantation can be performed successfully in octogenarians.
Spanish researchers have completed a large study showing that influenza vaccination just one month post-transplantation are safe.
Support for altruistic kidney donation appears to have more than doubled since 2001 in the United States.
Patients' one-year survival expectations more accurate than that of their nephrologist
Death risk increased by 55% if patients are rehospitalized within 30 days of kidney transplantation.
A study showed that the cost of immunosuppressive drugs for transplant recipients has declined substantially.
Angela Webster, MBBS, talks about why only certain patients should be screened for cancer post-transplant.
A number of single-center studies show that living kidney donation is associated with minimal morbidity and mortality.
Allograft function at one year post-transplant is more likely to be low if the donors are small.
Study finds a 60% increased likelihood of being hospitalized within 30 days of kidney transplant-related discharge.
Renal function improves over time in donors, declines with chronic kidney disease.
Reasons may include increasing prevalence of diabetes and obesity, economic disincentives, and transplant center oversight.
Systolic blood pressure of 160 mm Hg or higher raised death-censored graft loss risk twofold.
New findings could explain, at least in part, why live kidney donation has stagnated in the U.S.
Persistent need for dialysis at discharge increased the likelihood of readmission nearly threefold, study finds.
Plasma vitamin D levels increased to greater than 50 nmol/L in 80% of patients.
Recipients of kidneys from smokers are twice as likely to die as patients who get kidneys from nonsmokers.
From 2004 to 2010, the median fall in eGFR in the first year after donation grew significantly from 23.3 to 31.9 mL/min/1.73 m2.
Delayed graft function in patients aged 70 and older increased their death risk twofold.
The annual per-patient cost for kidney transplant recipients dropped from $33,040 in 2007 to $18,746 in 2011.
Cytomegalovirus viremia less likely with 200 rather than 100 days of valganciclovir after kidney transplantation.
Study characterizes cytomegalovirus infections in a large population of kidney transplant recipients.
In a study, vitamin D and calcium supplementation for one year made no difference in bone mineral density.
At-risk transplant recipients, however, have a lower risk of graft failure with prophylaxis than preemptive therapy.
Even blood pressure not considered hypertensive may reflect latent risk for adverse outcomes.
Improvements in immunosuppressive therapy have resulted in longer survival of kidney transplants, but they also may increase malignancies.
The objective is to eliminate the need for donors to travel to recipients' transplant centers to undergo nephrectomy.
Patients with ESRD may now have a tool to help them decide on kidney transplantation.
Greater efforts may be needed to educate patients with end-stage renal disease, especially African Americans.
Easing stenosis in transplanted renal arteries improves kidney function.
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NEPHROLOGY & UROLOGY NEWS
- Acute Kidney Injury (AKI)
- Chronic Kidney Disease (CKD)
- Contrast Nephropathy
- Cardiovascular Disease (CVD)
- Diabetic Nephropathy
- End-stage Renal Disease (ESRD)
- Lupus Nephritis
- Peritoneal Dialysis
- Secondary Hyperparathyroidism (SHPT)