Dual Kidney Transplant (DKT) May Improve Kidney Use

Dual Kidney Transplant (DKT) May Improve Kidney Use

Graft survival was similar to that seen in concurrent single SCD kidney recipients

Kidney Transplantation Followed by Drop in Sclerostin Levels

Kidney Transplantation Followed by Drop in Sclerostin Levels

Improved renal function may contribute to the decline in a glycoprotein that inhibits bone formation.

Kidney Failure From Polycystic Disease Linked to Better Outcomes

Kidney Failure From Polycystic Disease Linked to Better Outcomes

Patients are more likely to receive a kidney transplant and less likely to die than patients with end-stage renal disease from other causes.

Gender Disparity in Desire for Living Kidney Transplant

Gender Disparity in Desire for Living Kidney Transplant

Black female hemodialysis patients less likely to want living transplant; more likely to receive offer.

Survival Benefit of Expanded Criteria Kidneys Probed

Survival Benefit of Expanded Criteria Kidneys Probed

For some highly sensitized patients, expanded criteria donor kidneys do not confer a survival edge over standard criteria donor kidneys.

Circulatory Death, Brain-Dead Donor Kidneys Offer Equivalent Outcomes

Circulatory Death, Brain-Dead Donor Kidneys Offer Equivalent Outcomes

Kidney transplanted from brain-dead donors or those who died from circulatory causes are associated with similar patient and graft survival.

Transplant Induction Protocols Offer Similar Patient, Graft Survival

Transplant Induction Protocols Offer Similar Patient, Graft Survival

Study compared single-dose alemtuzumab and multiple-dose rabbit anti-thymocyte globulin.

Post-Transplant UTI Prophylaxis Protocol Addresses Sulfa Allergy

Post-Transplant UTI Prophylaxis Protocol Addresses Sulfa Allergy

Using cephalexin instead of trimethoprim-sulfamethoxazole may decrease UTI incidence and cost of care.

Risk Model Predicts Transplant Patient Readmission Risk

Risk Model Predicts Transplant Patient Readmission Risk

Less than a high school education and delayed graft function are among the factors that increase the risk of readmission within 30 days.

Prior Cancer Ups Death Risk After Kidney Transplantation

Prior Cancer Ups Death Risk After Kidney Transplantation

A pre-transplant history of malignancy increases the 10-year post-transplant mortality risk by 22%.

Older Age Predicts Renal Function Decline in Living Donors

Older Age Predicts Renal Function Decline in Living Donors

Mean estimated glomerular filtration rate decreases by 0.57 mL/min/1.73 m2 annually with each 1-year increase in age at donation.

Living Kidney Donors Are At Higher Gout Risk

Living Kidney Donors Are At Higher Gout Risk

In a study, donors were 60% more likely to be diagnosed with gout than matched healthy controls.

Kidney Donors Face Higher ESRD Risk

Kidney Donors Face Higher ESRD Risk

They also are at elevated risk of cardiovascular and all-cause mortality, study finds.

Kidney Donation Safe for Older Donors

Kidney Donation Safe for Older Donors

No differences found in mortality, CVD between donors, nondonors older than 55.

Nephron Sparing Surgery Okay for Tumors in Transplanted Kidneys

Nephron Sparing Surgery Okay for Tumors in Transplanted Kidneys

At last follow-up, 41 of 43 patients who underwent partial nephrectomy did not require dialysis.

Obesity Raises Risk of Delayed Renal Allograft Function

Obesity Raises Risk of Delayed Renal Allograft Function

Delayed graft function is 41% more likely in obese than non-obese kidney transplant recipients.

The Need for a Kidney Research Prize: Interview with Sharon Moe, MD

The Need for a Kidney Research Prize: Interview with Sharon Moe, MD

Dr. Moe spoke about the importance of nephrology research and how a prize competition can facilitate the process.

Fracture Risk Varies by Renal Replacement Therapy

Fracture Risk Varies by Renal Replacement Therapy

Hemodialysis patients are at higher risk than peritoneal dialysis and renal transplant recipients.

Acute Rejection Linked to Ketoconazole

Acute Rejection Linked to Ketoconazole

When administered concomitantly with tacrolimus in kidney transplant patients, it hiked the risk of acute rejection by more than 2-fold.

Transplant Outcomes Better in IgA Nephropathy Patients

Transplant Outcomes Better in IgA Nephropathy Patients

Their unadjusted 5-year death-censored graft survival and patient survival rates are higher compared with other recipients.

Kidney Transplants Less Likely in Overweight, Obese Women

Kidney Transplants Less Likely in Overweight, Obese Women

The odds of receiving a kidney decreased with increasing body mass index.

Sirolimus Reduces Post-Transplant HIV Levels

Sirolimus Reduces Post-Transplant HIV Levels

Lower post-transplant HIV DNA levels associated with sirolimus use.

Kidney Remaining After Donor Nephrectomy Increases in Size

Kidney Remaining After Donor Nephrectomy Increases in Size

Increment in renal parenchymal volume occurs within days after a kidney is removed from a living donor.

Post-Transplant Diabetes Risk Tied to BMI

Post-Transplant Diabetes Risk Tied to BMI

The risk of new-onset diabetes after a kidney transplant increases along with pretransplant body mass index.

Post-Transplant Hip Fracture Rate Declining

Post-Transplant Hip Fracture Rate Declining

Hip fractures remain an important complication following kidney transplantation, but incidence has decreased substantially.

Do you have any patients who acquired a kidney transplant abroad?

More than 90,000 kidney transplant candidates are on transplant waiting lists in the U.S.

Ribavirin May Treat HEV Infection in Transplant Recipients

Ribavirin May Treat HEV Infection in Transplant Recipients

Serum hepatitis E virus levels were undetectable in 78% of patients at least 6 months after stopping treatment.

Urine Test IDs Cause of Post-Transplant Kidney Problems

Urine Test IDs Cause of Post-Transplant Kidney Problems

By measuring urinary mRNA, a novel assay may enable clinicians to differentiate common causes of elevated creatinine.

Biopsy-Based Discard of Donor Kidneys May Be Misguided

Biopsy-Based Discard of Donor Kidneys May Be Misguided

Biopsies are of little value in determining overall risk of delayed organ function or even premature organ failure, researcher says.

Immunosuppression-Free Transplant: Interview with Suzanne Ildstad, MD

Immunosuppression-Free Transplant: Interview with Suzanne Ildstad, MD

Immunologic mismatch may no longer be a barrier between living kidney donors and recipients.

Kidney Donors at Slightly Higher ESRD Risk

Kidney Donors at Slightly Higher ESRD Risk

By age 80 years, the estimated lifetime risk of ESRD was 90 per 10,000 live donors compared with 326 per 10,000 in the general population.

Drug Shows Promise for Post-Transplant New-Onset Diabetes

Drug Shows Promise for Post-Transplant New-Onset Diabetes

Sitagliptin was well tolerated and it significantly increased insulin secretion and reduced glucose levels.

Geographic Differences for Children on Donor Waitlist

Geographic Differences for Children on Donor Waitlist

A new study is suggesting there is substantial geographic variation in deceased donor kidney waiting times.

High Ferritin Ups Infection Risk in Kidney Transplant Patients

High Ferritin Ups Infection Risk in Kidney Transplant Patients

Levels above 500 ng/mL predicted higher incidence rates of infections overall as well as bacterial and bloodstream infections.

Stem-Turned-Kidney Cells Pave Path to Organ Regeneration

Renal tissue could one day be created that would be functional as well as completely immunocompatible.

Transplanted Kidneys Can Harbor AIDS Virus

Transplanted Kidneys Can Harbor AIDS Virus

HIV-1 was found in podocytes or tubular cells of renal allografts in recipients who did not have detectable plasma levels of the virus.

Placing Very Elderly Patients on RRT

Placing Very Elderly Patients on RRT

As a venue for presenting important research on kidney disease to the world, Kidney Week never disappoints.

Multiple-Message Campaign May Increase Kidney Donation

Multiple-Message Campaign May Increase Kidney Donation

A new study from University of Illinois researchers suggests that it may be possible to increase kidney donation through a multiple-message campaign.

Solid Organ Transplantation May Raise Kidney Disease Risk in Children

Solid Organ Transplantation May Raise Kidney Disease Risk in Children

Children who undergo solid organ transplantation may have a high risk of developing kidney disease, according to a new national study.

Diabetes Hikes Infection-Related Death Risk Post-Transplant

Increasing age and receipt of a deceased-donor kidney were among risk factors for death from infection.

Living Donor Comorbidities Are Increasing, Study Finds

Complications and hospital lengths of stay after kidney donation declined from 10.1% and a mean 3.7 days, respectively.

Few Early Readmissions After Kidney Transplantation Preventable

In a study, only 8% of readmissions within 30 days of discharge met preventability criteria.

Study Sheds Light on Kidney Donors' Health Risks

Study Sheds Light on Kidney Donors' Health Risks

A new study has looked at the health of kidney donors and turned up some rather interesting findings in terms of short-term health risks.

Bacteremia in SOT Patients More Common Than Thought

'Even 100 days out the risk is still high and it is still going higher,' researcher says.

Prophylactic Regimen Effective Against PJP, Not Nocardiosis

Researchers evaluated sulfamethoxazole-trimethoprim single-strength twice-weekly in abdominal organ transplant patients.

Kidney Transplant Antibodies Predict Graft Loss, Injury

Kidney Transplant Antibodies Predict Graft Loss, Injury

Presence of complement-binding donor-specific antibodies increases risk of graft loss.

High BMI Predicts Adverse Transplant Outcomes

High risker of biopsy-proven acute rejection and death-censored graft failure observed in patients with a BMI of 35 kg/m2 or greater.

Belatacept's Renal Transplant Benefits Persist Long-Term

Even after five years on the drug, patients continue to have improved renal function compared with patients receiving cyclosporine A.

Drug May Work For Resistant CMV Infections in Transplant Recipients

Cidofovir cleared cytomegalovirus that was resistant to ganciclovir.

Adolescent Kidney Transplants More Likely to Fail

Patients who receive their first kidney transplant at ages 14-16 years appear to be at increased risk for transplant failure.

Kidney Donors Show Signs of Mild CKD

Donors had a decrease in GFR and an increase in parathyroid hormone and uric acid six months after nephrectomy.

Kidney Transplant Survival Less in the Severely Obese

At one-year post-transplant, the risk of death was reduced by 66% or more in transplant recipients with a BMI below 40, but was reduced by only 48% in recipients with a BMI of 40 or higher

Fluid Overload Increases Kidney Disease Progression Risk

Severe fluid overload in patients with advanced CKD increases by threefold the likelihood of initiation of renal replacement therapy.

Obese Found to Benefit from Robotic Kidney Transplants

Obese Found to Benefit from Robotic Kidney Transplants

Robotic kidney transplants may significantly improve outcomes in obese patients.

Social Media Initiative Ups Organ Donation Registration

Social Media Initiative Ups Organ Donation Registration

Social media is playing a significant role in organ donation registration.

Successful Kidney Transplantation Can Be Performed in Octogenarians

Successful Kidney Transplantation Can Be Performed in Octogenarians

A study shows that with appropriate screening and selection, kidney transplantation can be performed successfully in octogenarians.

Early Flu Shots Post-Transplant Safe, Effective

Early Flu Shots Post-Transplant Safe, Effective

Spanish researchers have completed a large study showing that influenza vaccination just one month post-transplantation are safe.

Americans' Support Growing for Altruistic Kidney Donation

Americans' Support Growing for Altruistic Kidney Donation

Support for altruistic kidney donation appears to have more than doubled since 2001 in the United States.

Dialysis Patients More Optimistic Than Their Doctors

Dialysis Patients More Optimistic Than Their Doctors

Patients' one-year survival expectations more accurate than that of their nephrologist

Early Post-Transplant Readmission a Bad Sign

Death risk increased by 55% if patients are rehospitalized within 30 days of kidney transplantation.

What is the impact of immunosuppressive drug costs on adherence to therapy?

A study showed that the cost of immunosuppressive drugs for transplant recipients has declined substantially.

Angela Webster, MBBS: Screening for common cancers post-transplant

Angela Webster, MBBS, talks about why only certain patients should be screened for cancer post-transplant.

Should kidney transplant programs provide long-term follow-up of living kidney donors?

A number of single-center studies show that living kidney donation is associated with minimal morbidity and mortality.

Living Donor Size Affects Kidney Transplant Outcomes

Allograft function at one year post-transplant is more likely to be low if the donors are small.

Early Post-Transplant Readmission Linked to Frailty

Study finds a 60% increased likelihood of being hospitalized within 30 days of kidney transplant-related discharge.

Low GFR Post-Kidney Donation Not CKD

Renal function improves over time in donors, declines with chronic kidney disease.

Living Kidney Donation Declining in U.S.

Reasons may include increasing prevalence of diabetes and obesity, economic disincentives, and transplant center oversight.

Too Much Salt Raises Post-Transplant Hypertension Risk

Systolic blood pressure of 160 mm Hg or higher raised death-censored graft loss risk twofold.

Obesity Often Thwarts Living Kidney Donation

New findings could explain, at least in part, why live kidney donation has stagnated in the U.S.

Post-Transplant Dialysis Need Predicts Early Readmission

Persistent need for dialysis at discharge increased the likelihood of readmission nearly threefold, study finds.

Vitamin D Deficient Tx Patients Benefit from Oral Cholecalciferol

Plasma vitamin D levels increased to greater than 50 nmol/L in 80% of patients.

Transplant Patient Death Risk Higher If Donors Are Smokers

Recipients of kidneys from smokers are twice as likely to die as patients who get kidneys from nonsmokers.

Living Kidney Donors Facing More Rapid Declines in Renal Function

From 2004 to 2010, the median fall in eGFR in the first year after donation grew significantly from 23.3 to 31.9 mL/min/1.73 m2.

DGF-Associated Mortality Higher in the Elderly

Delayed graft function in patients aged 70 and older increased their death risk twofold.

Immunosuppressive Drug Costs Decline, But Still Expensive

The annual per-patient cost for kidney transplant recipients dropped from $33,040 in 2007 to $18,746 in 2011.

Longer CMV Prophylaxis May Be Better

Cytomegalovirus viremia less likely with 200 rather than 100 days of valganciclovir after kidney transplantation.

Post-Transplant CMV Infection Hits GI Tract Hardest

Study characterizes cytomegalovirus infections in a large population of kidney transplant recipients.

Post-Transplant Bone Preservation Strategy Not Helpful

In a study, vitamin D and calcium supplementation for one year made no difference in bone mineral density.

Strategies Offer Similar Protection from CMV Disease

At-risk transplant recipients, however, have a lower risk of graft failure with prophylaxis than preemptive therapy.

Blood Pressure Rises Observed in Living Kidney Donors

Even blood pressure not considered hypertensive may reflect latent risk for adverse outcomes.

Is screening for cancer warranted following a kidney transplant?

Improvements in immunosuppressive therapy have resulted in longer survival of kidney transplants, but they also may increase malignancies.

Donor Criteria Consensus Sought in Canada

The objective is to eliminate the need for donors to travel to recipients' transplant centers to undergo nephrectomy.

Web-Based Tool May Aid Kidney Transplant Decisions

Web-Based Tool May Aid Kidney Transplant Decisions

Patients with ESRD may now have a tool to help them decide on kidney transplantation.

Study Highlights Need To Bolster Efforts to Educate ESRD Patients

Study Highlights Need To Bolster Efforts to Educate ESRD Patients

Greater efforts may be needed to educate patients with end-stage renal disease, especially African Americans.

Renal Artery Stenting May Protect Allografts

Easing stenosis in transplanted renal arteries improves kidney function.

Financial Barriers May Be Hampering Paired Kidney Exchanges

Financial Barriers May Be Hampering Paired Kidney Exchanges

Paired kidney exchanges are not as popular because there is no way for insurance companies to determine which company pays for which donor's surgery.

Ureteral Stents Hike BK Viruria, Viremia Risk in Transplant Patients

Researchers recommend BK virus screening for all kidney transplant recipients.

Abnormal BP Raises Delayed Graft Function Risk

Study implicates low diastolic and high systolic pressure immediately after kidney transplantation.

Prostate Cancer Need Not Preclude Kidney Transplants

Five-year mortality is lower among PCa patients who receive a transplant rather than stay on dialysis.

Pre-Transplant Cancers Might Be Overlooked

In a study, 44% of neoplasias detected within a year of transplantation may have been present prior to surgery.

Longer Time on Dialysis Post-Tx Associated with Worse Outcomes

Patients needing dialysis for at least two weeks after receiving a kidney had lower eGFR at one year.

Post-Transplant New-Onset Diabetes Linked to Low Magnesium

Low serum magnesium found to increase the risk by nearly 50%.

Old Age Alone Should Not Prevent Kidney Transplants

Recipients older than 65 had rates of delayed graft function and graft loss at one year similar to those of younger recipients.

Combo Flu Shot Safe in Pediatric Kidney Transplant Patients

No anti-HLA antibodies developed following administration of the influenza A/H1N1 vaccine.

Islet Transplants Promising for Diabetics

Islet Transplants Promising for Diabetics

A new study shows that islet transplantation for type-1 diabetics achieves insulin independence and reverses progression.

Older Circulatory-Death Donor Kidneys Acceptable for Transplant

Graft loss risk is the same as with kidneys from brain-death donors.

Donor Kidney Volume Predicts Graft Survival

Recipients of relatively large kidneys have higher eGFRs up to five years post-transplant.

Kidney Transplant Chains Boost Benefit

Altruistic nondirected donors triggered nearly five transplants, more if the donors were blood type O.

Cardiovascular Events in Kidney Transplant Patients Linked to CMV

Cytomegalovirus exposure prior to transplantation independently increases the risk for atherosclerotic events by 80%.

Do you think patients with lupus nephritis can be good renal transplant candidates if their disease has been quiescent for at least one year?

In a recent study researchers examined transplant outcomes in patients with lupus nephritis who had no clinical evidence of disease in the year prior.

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