Highest level of opioid use in the year prior to transplantation was associated with a 45% and 28% increased risk of death and graft loss, respectively.
In a study, diabetes in both the donor and recipient was associated with triple the risk of death at 5 years post-transplant compared with the absence of diabetes in both the donor and recipient.
Post-transplant UTI rates were lower when cephalexin was added to SMX-TMP than when SMX-TMP was used alone (7.5% vs 25.8%), study finds.
Kidney transplant recipients who experienced an episode of bacteremia had double the risks of graft failure and death.
Older patients with a Charlson Comorbidity Index score below 5 had a higher 3-year survival rate than those with a score of 5 or higher (90% vs 76%).
High-KDPI kidneys can improve the likelihood of a functioning graft compared with waiting for a superior kidney.
Venous thromboembolism is associated with a 4.1-fold increased risk of death and a 2.3-fold increased risk of death-censored graft loss among kidney transplant recipients.
Risk factors include impaired renal function and inadequate hydration prior to contrast exposure.
Angioplasty plus stenting is associated with less residual stenosis and a lower restenosis rate compared with angioplasty alone.
Researchers report that matching deceased kidney donors and kidney recipients by cytomegalovirus serostatus optimizes high- and low-risk profiles.
Five-year graft survival rates among recipients of kidneys from living donors increased from 76.6% in 1985-1894 to 85.4% in 2009-2015.
The adjusted 5-year risk of insulin use following donation is 5 times higher among obese vs normal weight donors.
In a study of renal transplant patients who received ureteral stents, ciprofloxacin did not lower the incidence of UTI compared with SMX-TMP.
Cinacalcet treatment may serve as a bridge to parathyroidectomy or as an alternative, researchers say.
Among 1734 childhood recipients, 289 developed cancer over a median follow-up of 13.4 years.
Graft failure risk was highest when a recipient of a kidney from a donor of the opposite sex was more than 66 pounds heavier than the donor.
Study supports transplant of kidneys into sensitized patients.
Hospitals that managed the most deceased donors were 1.5 times more likely to recover 4 or more transplantable organs than those that managed the least.
Acute ST-segment elevation myocardial infarction (STEMI) accounted for 29.3% of RTR admissions.
From 2015 to 2016, the number of organ transplants rose from 30,969 to 33,595; the number of kidney transplants increased from 17,878 to 19,061.
Investigators observed no difference in hemoglobin level between transplant recipients and non-transplant CKD patients starting hemodialysis.
Activation of latent HPV infections may contribute to the increased risk of HPV-related (pre)malignant lesions in female RTRs.
End-stage renal disease is nearly 1.9 times more likely to develop in donors with a body mass index of 30 kg/m2 or higher.
Similar survival rates seen whether organ comes from 50-year-old or octogenarian.
The researchers found that all patients treated for 12 and 24 weeks achieved sustained virologic response at 12 weeks after therapy ended.
Organs from CI-positive donors were associated with higher mortality.
While antiretroviral therapy has allowed HIV patients to undergo kidney transplantation, allograft rejection remains high in this group.
Fracture incidence within a year of transplant was 3 times lower among patients who had surgery from 2009 to 2011 vs 2004 to 2006.
Bone turnover markers increased following unilateral nephrectomy.
All recipients should have full-body skin evaluations after transplant surgery, regardless of ethnicity.
Therapy was associated with a significant improvement in bone mineral density at the lumbar spine and femoral neck.
Living kidney donor costs up with higher degree of allosensitization; also linked to obesity.
Guidelines for kidney recipients differ on frequency of cancer screenings.
Study reveals a significantly higher risk of a 50% or greater decline in eGFR and end-stage graft failure.
The availability of direct-acting antiviral drugs may enable eradication of hepatitis C virus and improve outcomes.
Major fractures included the proximal humerus, forearm, hip, and clinical vertebral fractures.
Study also links smoking with a decreased likelihood of receiving a kidney transplant.
Inhibition with http://www.renalandurologynews.com/transplantation/section/635/ occurs after virus entry but before DNA replication.
Recipients of kidneys from individuals who donated the organs after cardiac death are more likely to experience graft loss and delayed graft function.
Researchers highlighted the benefit of iPTH monitoring.
HIV retransplant recipients have increased risk of death and graft loss versus HIV re-KT patients
Possible reasons include malabsorption of immunosuppressive drugs and deposition of oxalate crystals in transplanted kidneys.
Rates of non-adherence to follow-up care and medication regimens also found to differ by race.
Some donors spend years on dialysis before being placed on the kidney transplant waiting list.
Each Hounsfield unit increase on CT is associated with a 7% decreased risk of death among waitlisted kidney transplant candidates.
Coronary artery disease before transplantation increases death risk by 77%, study finds.
An eGFR decline of at least 30% during the 6 to 24 months after kidney transplantation predicts a higher risk of graft loss.
In a study, viral infections occurred in 52.4% of patients with a BMI of 35 kg/m2 or higher compared with 37.1% of those with a lower BMI.
The 15-hour surgery took place in early May.
Deceased donor kidneys obtained on Friday or Saturday were 16% more likely to be discarded than transplanted, compared with organs gathered other days of the week.
Oral nicotinamide has been linked to nonsignificant reductions in new, non-melanoma skin cancers in renal transplant patients.
Nearly 28% of deceased-donor kidney transplants in the US were performed on the weekends.
Only this histologic variant occurs at a significantly higher incidence in renal allograft recipients than the non-transplant population.
At 24 months follow up, no difference was found in primary outcomes in those treated for asymptomatic bacteriuria.
Uninsured live kidney donors are more likely to have multiple health risk factors.
Increased likelihood of delayed graft function and graft loss observed in recipients of kidneys from donors older than 50 years.
Nearly 70% of survey respondents indicated that, if compensated, they would donate a kidney to anyone in need.
Survival rates are lower among patients who receive a deceased-donor kidney or remain on the transplant waiting list.
Transmission of HEV through plasma exchange for acute humoral rejection after kidney transplant.
At 7 years after kidney transplantation, belatacept recipients had lower risks of death and graft loss than those treated with cyclosporine.
Cancer second leading cause of death in solid-organ transplant recipients.
Increased left ventricular mass found in donors with even mild decreases in renal function.
Screening not linked to improved patient survival after transplant; may delay time to listing, transplant.
Blacks undergoing PD or home HD and Hispanics undergoing PD are less likely than their white counterparts to receive a kidney transplant.
The risk of bladder outlet obstruction increased 34% per unit increase in serum PSA and decreased 23% per unit increase in maximal flow rate.
Just over half of kidneys from deceased ECD/DCD donors are not used, study finds.
If ESRD patients face increasing difficulty getting a kidney transplant in coming years, they may see an artificial kidney as the next best alternative.
In a study, ramipril was not significantly better than placebo in preserving renal function in kidney transplant recipients.
Dialysis, organ transplant may increase odds for certain types of cancer.
Overall one- and ten-year survival rates of the transplanted organs in commercial recipients compared with controls were 91% and 22% vs. 98% and 44%.
Meta-analysis suggests a 9% decreased 5-year mortality risk associated with pre-transplant peritoneal dialysis versus hemodialysis.
The association is independent of anemia, according to researchers.
10% rise in antibiotic resistance would lead to 2,100 more deaths, 40,000 more infections yearly.
Found to have higher mortality, readmission, surgical costs after controlling for patient factors.
Reduction in left ventricular hypertrophy predicts a decreased long-term risk of death and cardiovascular events, study finds.
Hypomagnesemia after a kidney transplant is associated with a 58% increased risk of new-onset diabetes.
Researchers find an association between late-onset BK virus nephropathy and less adherence to screening guidelines.
Kidneys from blood culture positive donors are not associated with graft and patient survival, however.
Findings in de novo kidney recipients receiving no pharmacologic CMV prophylaxis.
Review indicates that doctors who operate the night before another surgery do well.
They have double the risk of invasive melanoma and triple the risk of dying from it.
Patients who listened to music had less pain, anxiety, and analgesia use after their operations, compared with patients receiving routine care or non-drug interventions.
Findings among end-stage renal disease patients initiating dialysis in Georgia.
The main independent determinants are circulating donor-specific anti-HLA antibody and cold ischemia time.
From 1988 to 2010, establishment of organ donation registries, tax incentives, and paid leave have had no significant effect.
Risk of delayed graft function is reduced when donors are maintained at a temperature of 93.2° to 95° F prior to kidney harvesting after death.
No difference between defined BMI bands in patient or graft survival for transplanted patients.
Female kidney recipients have a nearly 7-fold higher risk of UTI than their male counterparts.
Limited effect among adult patients during 5 years following kidney transplantation.
Ongoing study suggests that renal function continues to increase after donation but decreases in donation-eligible controls.
Overall, men with LUTS showed remarkably poor knowledge about their symptoms.
Donor and recipient outcomes are similar to those associated with laparoscopic removal of left donor kidneys.
Highest versus lowest intake associated with a 67% and 88% lower risk of all-cause and cardiovascular mortality, respectively.
It's time to reward people willing to save a stranger, researchers say.
While whites more likely to donate, report found race not the only driving factor.
Their risk of a stroke was 46% lower than that of dialysis patients.
Although ban was lifted on such surgeries in 2013, none have taken place, researchers say.
The researchers found that 96% of donors reported one or more direct costs, totaling $101,484 (mean $523).
Patients discharged with home health or to a skilled nursing facility also were more likely to be readmitted.
At the end of a 22-year study period, the 1- and 3-year risk of graft loss did not differs significantly between black and white recipients.
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NEPHROLOGY & UROLOGY NEWS
- Acute Kidney Injury (AKI)
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- End-stage Renal Disease (ESRD)
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- Secondary Hyperparathyroidism (SHPT)