BMI Doesn't Affect Kidney Transplant Survival

BMI Doesn't Affect Kidney Transplant Survival

No difference between defined BMI bands in patient or graft survival for transplanted patients.

Post-Transplant UTI Risk Factors Identified

Post-Transplant UTI Risk Factors Identified

Female kidney recipients have a nearly 7-fold higher risk of UTI than their male counterparts.

Steroid Withdrawal May Not Prevent Post-transplant Diabetes

Steroid Withdrawal May Not Prevent Post-transplant Diabetes

Limited effect among adult patients during 5 years following kidney transplantation.

Living Kidney Donation Relatively Safe

Living Kidney Donation Relatively Safe

Ongoing study suggests that renal function continues to increase after donation but decreases in donation-eligible controls.

Laparoscopically Harvesting Right Kidneys from Living Donors Safe

Laparoscopically Harvesting Right Kidneys from Living Donors Safe

Donor and recipient outcomes are similar to those associated with laparoscopic removal of left donor kidneys.

High n-3 PUFA Intake Improves Survival After Kidney Transplantation

High n-3 PUFA Intake Improves Survival After Kidney Transplantation

Highest versus lowest intake associated with a 67% and 88% lower risk of all-cause and cardiovascular mortality, respectively.

Paying Donors May Help Organ Shortage

Paying Donors May Help Organ Shortage

It's time to reward people willing to save a stranger, researchers say.

Organ Donation Rates in the United States

Organ Donation Rates in the United States

While whites more likely to donate, report found race not the only driving factor.

Stroke Risk Lower with Kidney Transplants vs. Dialysis

Stroke Risk Lower with Kidney Transplants vs. Dialysis

Their risk of a stroke was 46% lower than that of dialysis patients.

Slow Adoption of HIV-Positive Organ Donations

Slow Adoption of HIV-Positive Organ Donations

Although ban was lifted on such surgeries in 2013, none have taken place, researchers say.

Transplant-Related Costs Incurred by Living Kidney Donors

Transplant-Related Costs Incurred by Living Kidney Donors

The researchers found that 96% of donors reported one or more direct costs, totaling $101,484 (mean $523).

Discharge Disposition Affects Transplant Patient Readmission Risk

Discharge Disposition Affects Transplant Patient Readmission Risk

Patients discharged with home health or to a skilled nursing facility also were more likely to be readmitted.

Race Gap in Kidney Transplant Outcomes Narrows Dramatically

Race Gap in Kidney Transplant Outcomes Narrows Dramatically

At the end of a 22-year study period, the 1- and 3-year risk of graft loss did not differs significantly between black and white recipients.

Contrast-Induced Nephropathy in Kidney Tx Patients Characterized

Contrast-Induced Nephropathy in Kidney Tx Patients Characterized

Study reveals a 13% incidence of CIN in allograft recipients undergoing computed tomography or cardiac catheterization with contrast media.

Post-Transplant Renal Function Decline Predicts Worse Outcomes

Post-Transplant Renal Function Decline Predicts Worse Outcomes

A 30% decline in eGFR between 1 and 3 years post-transplant is associated with an increased risk of all-cause graft loss and patient death.

PPIs, Low Magnesium Linked in Renal Transplant Patients

PPIs, Low Magnesium Linked in Renal Transplant Patients

Study of renal transplant patients also shows that proton pump inhibitors are associated with increased arterial stiffness.

Diabetic Donor Kidneys Associated with Worse Outcomes

Diabetic Donor Kidneys Associated with Worse Outcomes

Recipients of diabetic donor kidneys—especially diabetic recipients—are at increased risk of graft loss and death.

Donor Kidneys Usable Despite Acute Kidney Injury

Donor Kidneys Usable Despite Acute Kidney Injury

Recipients of AKI kidneys have patient and graft survival rates similar to those of recipients of non-AKI kidneys.

Weight Loss May Lower the Risk of Post-Transplant New-Onset Diabetes

Weight Loss May Lower the Risk of Post-Transplant New-Onset Diabetes

Kidney recipients who lost the most weight prior to transplantation had a 25% decreased risk versus those with the most weight gain.

Elderly Kidney Transplant Recipients Fare Better with Younger Donors

Elderly Kidney Transplant Recipients Fare Better with Younger Donors

Recipients aged 65 years and older who receive kidneys from donors in the same age group have a higher risk of death and delayed graft function.

Old Age Need Not Rule Out Renal Transplants

Old Age Need Not Rule Out Renal Transplants

New findings show that even patients in their 80s can benefit.

BMI Mismatch Increases Risk of Kidney Allograft Loss

BMI Mismatch Increases Risk of Kidney Allograft Loss

Each 1 kg/m2 increment in BMI difference between recipients and deceased donors is associated with a 6% increased risk of graft loss.

Motor Vehicle Program Signs Up Additional Organ Donors

Motor Vehicle Program Signs Up Additional Organ Donors

DMV staff who received training were more likely to register customers as organ donors.

Whatever Happened to the AIDS Crisis?

Whatever Happened to the AIDS Crisis?

Chronic diseases such as end-stage renal disease (ESRD) have now surpassed opportunistic infections as the leading cause of death among HIV-infected patients.

Kidney Transplantation More Successful in HIV Than Hepatitis C

Kidney Transplantation More Successful in HIV Than Hepatitis C

Refuting common wisdom, research shows that HIV patients fared better than those with hepatitis C.

Older Donor Kidneys Good for Seniors

Older Donor Kidneys Good for Seniors

Many of these organs would otherwise get discarded, researcher says.

Study Backs Renal Transplantation in HIV-Infected Patients

Study Backs Renal Transplantation in HIV-Infected Patients

In the absence of co-infection with hepatitis C virus, their graft and patient survival rates are similar to those of HIV-negative patients.

Older Blood Okay for Blood Transfusions in ICU Patients

Older Blood Okay for Blood Transfusions in ICU Patients

Trial shows that changes to blood during storage do not affect quality.

Kidney Failure Undertreatment an International Concern

Kidney Failure Undertreatment an International Concern

Dire need for low-cost dialysis techniques that could be used worldwide, researcher says

Some Injured Kidneys Suitable for Transplant

Some Injured Kidneys Suitable for Transplant

For reasons that are unclear, certain organs even performed better 6 months after transplant

HIV-Positive Kidney Transplantation Possible

HIV-Positive Kidney Transplantation Possible

South African researchers report 'impressive' results in 27 cases

Kidney Transplant Timing Matters Little to Pregnancy

Kidney Transplant Timing Matters Little to Pregnancy

Pregnancy outcomes similar for women who received kidney whether as a child or an adult.

With Donor Kidneys, Every Hour of Cold Ischemia Time Matters

With Donor Kidneys, Every Hour of Cold Ischemia Time Matters

The longer a kidney is without a blood supply, the greater the risk of graft failure and death, according to a new study.

Study Highlights Survival Benefit of Solid-Organ Transplants

Study Highlights Survival Benefit of Solid-Organ Transplants

Kidney transplants alone saved nearly 1.4 million life-years in the United States over a 25-year period.

USRDS: Kidney Disease on the Rise, but Patients Faring Better

USRDS: Kidney Disease on the Rise, but Patients Faring Better

Even though rate of disease is on the rise, fewer patients are suffering organ failure or dying

FDA Approves System to Reduce Pathogens in Donated Blood Plasma

FDA Approves System to Reduce Pathogens in Donated Blood Plasma

Targeted pathogens include AIDS-causing HIV, hepatitis B and C, and the West Nile virus

New U.S. Kidney Transplant Rules Take Effect

New U.S. Kidney Transplant Rules Take Effect

The changes to kidney transplant rules are intended to make organ allocation more equitable.

Genetic Marker May Help Improve Kidney Transplant Outcomes

Genetic Marker May Help Improve Kidney Transplant Outcomes

Researchers identified a genetic glitch that promotes kidney scarring.

Prior Kidney Donor Favorable Waitlist Policy is Working

Prior Kidney Donor Favorable Waitlist Policy is Working

Living kidney donors who are in need of a transplant later in life experience shorter wait times and receive better quality kidneys.

Once Pregnant, Living Kidney Donors More Likely to Have Hypertension

Once Pregnant, Living Kidney Donors More Likely to Have Hypertension

Living kidney donors are more likely to be diagnosed with high blood pressure or preemclampsia once pregnant compared to non-donor.

Anticoagulants May Protect Transplanted Kidneys After Surgery

Anticoagulants May Protect Transplanted Kidneys After Surgery

An anticoagulant was found to preserve kidney function after transplantation.

Possible Tissue Injury Predictor in Transplant Recipients Found

Possible Tissue Injury Predictor in Transplant Recipients Found

Researchers may have found a predictor for focal segmental glomerulosclerosis (FSGS) in kidney transplant recipients.

More Compensation for Living Kidney Donors, Urge Nephrologists

More Compensation for Living Kidney Donors, Urge Nephrologists

More reimbursement and compensation opportunities should be available for living kidney donors.

Transplant Plus Native Nephrectomy May Benefit Polycystic Kidney Disease (ADPKD) Patients

Transplant Plus Native Nephrectomy May Benefit Polycystic Kidney Disease (ADPKD) Patients

This approach resulted in improved hypertension control in patients with autosomal dominant polycystic kidney disease, new study found.

Many Kidney Failure Patients Unaware of Transplant Benefits

Many Kidney Failure Patients Unaware of Transplant Benefits

The vast majority of kidney failure patients reported that they were doing fine on dialysis and did not see a need for a kidney transplant.

Wearable Artificial Kidney Greenlit For Safety Testing

Wearable Artificial Kidney Greenlit For Safety Testing

Researchers expect to start safety and performance testing of the Wearable Artificial Kidney (WAK) this autumn.

Post-Transplant Renal Cell Carcinoma Risk Factors Identified

Post-Transplant Renal Cell Carcinoma Risk Factors Identified

Ultrasound surveillance for renal tumors should be performed on native and graft kidneys from 3 years after transplantation.

Living Kidney Donor Dilemma: Willing But Unable to Donate

Living Kidney Donor Dilemma: Willing But Unable to Donate

Barriers to donation may explain why living donor kidney transplantation has been declining.

Post-Transplant Urologic Cancers More Likely in Women

Post-Transplant Urologic Cancers More Likely in Women

In adjusted analyses, female transplant recipients had a significantly increased risk of urologic cancer and men did not.

Dual Kidney Transplant (DKT) May Improve Kidney Use

Dual Kidney Transplant (DKT) May Improve Kidney Use

Graft survival was similar to that seen in concurrent single SCD kidney recipients

Kidney Transplantation Followed by Drop in Sclerostin Levels

Kidney Transplantation Followed by Drop in Sclerostin Levels

Improved renal function may contribute to the decline in a glycoprotein that inhibits bone formation.

Kidney Failure From Polycystic Disease Linked to Better Outcomes

Kidney Failure From Polycystic Disease Linked to Better Outcomes

Patients are more likely to receive a kidney transplant and less likely to die than patients with end-stage renal disease from other causes.

Gender Disparity in Desire for Living Kidney Transplant

Gender Disparity in Desire for Living Kidney Transplant

Black female hemodialysis patients less likely to want living transplant; more likely to receive offer.

Survival Benefit of Expanded Criteria Kidneys Probed

Survival Benefit of Expanded Criteria Kidneys Probed

For some highly sensitized patients, expanded criteria donor kidneys do not confer a survival edge over standard criteria donor kidneys.

Circulatory Death, Brain-Dead Donor Kidneys Offer Equivalent Outcomes

Circulatory Death, Brain-Dead Donor Kidneys Offer Equivalent Outcomes

Kidney transplanted from brain-dead donors or those who died from circulatory causes are associated with similar patient and graft survival.

Transplant Induction Protocols Offer Similar Patient, Graft Survival

Transplant Induction Protocols Offer Similar Patient, Graft Survival

Study compared single-dose alemtuzumab and multiple-dose rabbit anti-thymocyte globulin.

Post-Transplant UTI Prophylaxis Protocol Addresses Sulfa Allergy

Post-Transplant UTI Prophylaxis Protocol Addresses Sulfa Allergy

Using cephalexin instead of trimethoprim-sulfamethoxazole may decrease UTI incidence and cost of care.

Risk Model Predicts Transplant Patient Readmission Risk

Risk Model Predicts Transplant Patient Readmission Risk

Less than a high school education and delayed graft function are among the factors that increase the risk of readmission within 30 days.

Prior Cancer Ups Death Risk After Kidney Transplantation

Prior Cancer Ups Death Risk After Kidney Transplantation

A pre-transplant history of malignancy increases the 10-year post-transplant mortality risk by 22%.

Older Age Predicts Renal Function Decline in Living Donors

Older Age Predicts Renal Function Decline in Living Donors

Mean estimated glomerular filtration rate decreases by 0.57 mL/min/1.73 m2 annually with each 1-year increase in age at donation.

Living Kidney Donors Are At Higher Gout Risk

Living Kidney Donors Are At Higher Gout Risk

In a study, donors were 60% more likely to be diagnosed with gout than matched healthy controls.

Kidney Donors Face Higher ESRD Risk

Kidney Donors Face Higher ESRD Risk

They also are at elevated risk of cardiovascular and all-cause mortality, study finds.

Kidney Donation Safe for Older Donors

Kidney Donation Safe for Older Donors

No differences found in mortality, CVD between donors, nondonors older than 55.

Nephron Sparing Surgery Okay for Tumors in Transplanted Kidneys

Nephron Sparing Surgery Okay for Tumors in Transplanted Kidneys

At last follow-up, 41 of 43 patients who underwent partial nephrectomy did not require dialysis.

Obesity Raises Risk of Delayed Renal Allograft Function

Obesity Raises Risk of Delayed Renal Allograft Function

Delayed graft function is 41% more likely in obese than non-obese kidney transplant recipients.

The Need for a Kidney Research Prize: Interview with Sharon Moe, MD

The Need for a Kidney Research Prize: Interview with Sharon Moe, MD

Dr. Moe spoke about the importance of nephrology research and how a prize competition can facilitate the process.

Fracture Risk Varies by Renal Replacement Therapy

Fracture Risk Varies by Renal Replacement Therapy

Hemodialysis patients are at higher risk than peritoneal dialysis and renal transplant recipients.

Acute Rejection Linked to Ketoconazole

Acute Rejection Linked to Ketoconazole

When administered concomitantly with tacrolimus in kidney transplant patients, it hiked the risk of acute rejection by more than 2-fold.

Transplant Outcomes Better in IgA Nephropathy Patients

Transplant Outcomes Better in IgA Nephropathy Patients

Their unadjusted 5-year death-censored graft survival and patient survival rates are higher compared with other recipients.

Kidney Transplants Less Likely in Overweight, Obese Women

Kidney Transplants Less Likely in Overweight, Obese Women

The odds of receiving a kidney decreased with increasing body mass index.

Sirolimus Reduces Post-Transplant HIV Levels

Sirolimus Reduces Post-Transplant HIV Levels

Lower post-transplant HIV DNA levels associated with sirolimus use.

Kidney Remaining After Donor Nephrectomy Increases in Size

Kidney Remaining After Donor Nephrectomy Increases in Size

Increment in renal parenchymal volume occurs within days after a kidney is removed from a living donor.

Post-Transplant Diabetes Risk Tied to BMI

Post-Transplant Diabetes Risk Tied to BMI

The risk of new-onset diabetes after a kidney transplant increases along with pretransplant body mass index.

Post-Transplant Hip Fracture Rate Declining

Post-Transplant Hip Fracture Rate Declining

Hip fractures remain an important complication following kidney transplantation, but incidence has decreased substantially.

Do you have any patients who acquired a kidney transplant abroad?

More than 90,000 kidney transplant candidates are on transplant waiting lists in the U.S.

Ribavirin May Treat HEV Infection in Transplant Recipients

Ribavirin May Treat HEV Infection in Transplant Recipients

Serum hepatitis E virus levels were undetectable in 78% of patients at least 6 months after stopping treatment.

Urine Test IDs Cause of Post-Transplant Kidney Problems

Urine Test IDs Cause of Post-Transplant Kidney Problems

By measuring urinary mRNA, a novel assay may enable clinicians to differentiate common causes of elevated creatinine.

Biopsy-Based Discard of Donor Kidneys May Be Misguided

Biopsy-Based Discard of Donor Kidneys May Be Misguided

Biopsies are of little value in determining overall risk of delayed organ function or even premature organ failure, researcher says.

Immunosuppression-Free Transplant: Interview with Suzanne Ildstad, MD

Immunosuppression-Free Transplant: Interview with Suzanne Ildstad, MD

Immunologic mismatch may no longer be a barrier between living kidney donors and recipients.

Kidney Donors at Slightly Higher ESRD Risk

Kidney Donors at Slightly Higher ESRD Risk

By age 80 years, the estimated lifetime risk of ESRD was 90 per 10,000 live donors compared with 326 per 10,000 in the general population.

Drug Shows Promise for Post-Transplant New-Onset Diabetes

Drug Shows Promise for Post-Transplant New-Onset Diabetes

Sitagliptin was well tolerated and it significantly increased insulin secretion and reduced glucose levels.

Geographic Differences for Children on Donor Waitlist

Geographic Differences for Children on Donor Waitlist

A new study is suggesting there is substantial geographic variation in deceased donor kidney waiting times.

High Ferritin Ups Infection Risk in Kidney Transplant Patients

High Ferritin Ups Infection Risk in Kidney Transplant Patients

Levels above 500 ng/mL predicted higher incidence rates of infections overall as well as bacterial and bloodstream infections.

Stem-Turned-Kidney Cells Pave Path to Organ Regeneration

Renal tissue could one day be created that would be functional as well as completely immunocompatible.

Transplanted Kidneys Can Harbor AIDS Virus

Transplanted Kidneys Can Harbor AIDS Virus

HIV-1 was found in podocytes or tubular cells of renal allografts in recipients who did not have detectable plasma levels of the virus.

Placing Very Elderly Patients on RRT

Placing Very Elderly Patients on RRT

As a venue for presenting important research on kidney disease to the world, Kidney Week never disappoints.

Multiple-Message Campaign May Increase Kidney Donation

Multiple-Message Campaign May Increase Kidney Donation

A new study from University of Illinois researchers suggests that it may be possible to increase kidney donation through a multiple-message campaign.

Solid Organ Transplantation May Raise Kidney Disease Risk in Children

Solid Organ Transplantation May Raise Kidney Disease Risk in Children

Children who undergo solid organ transplantation may have a high risk of developing kidney disease, according to a new national study.

Diabetes Hikes Infection-Related Death Risk Post-Transplant

Increasing age and receipt of a deceased-donor kidney were among risk factors for death from infection.

Living Donor Comorbidities Are Increasing, Study Finds

Complications and hospital lengths of stay after kidney donation declined from 10.1% and a mean 3.7 days, respectively.

Few Early Readmissions After Kidney Transplantation Preventable

In a study, only 8% of readmissions within 30 days of discharge met preventability criteria.

Study Sheds Light on Kidney Donors' Health Risks

Study Sheds Light on Kidney Donors' Health Risks

A new study has looked at the health of kidney donors and turned up some rather interesting findings in terms of short-term health risks.

Bacteremia in SOT Patients More Common Than Thought

'Even 100 days out the risk is still high and it is still going higher,' researcher says.

Prophylactic Regimen Effective Against PJP, Not Nocardiosis

Researchers evaluated sulfamethoxazole-trimethoprim single-strength twice-weekly in abdominal organ transplant patients.

Kidney Transplant Antibodies Predict Graft Loss, Injury

Kidney Transplant Antibodies Predict Graft Loss, Injury

Presence of complement-binding donor-specific antibodies increases risk of graft loss.

High BMI Predicts Adverse Transplant Outcomes

High risker of biopsy-proven acute rejection and death-censored graft failure observed in patients with a BMI of 35 kg/m2 or greater.

Belatacept's Renal Transplant Benefits Persist Long-Term

Even after five years on the drug, patients continue to have improved renal function compared with patients receiving cyclosporine A.

Drug May Work For Resistant CMV Infections in Transplant Recipients

Cidofovir cleared cytomegalovirus that was resistant to ganciclovir.

Adolescent Kidney Transplants More Likely to Fail

Patients who receive their first kidney transplant at ages 14-16 years appear to be at increased risk for transplant failure.

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