Tadalafil Found to Ease Ejaculatory Problems

Tadalafil (Cialis) may help to ease ejaculatory or orgasmic dysfunction in men with erectile dysfunction (ED), according to an analysis of data from 3,581 men enrolled in 17 randomized, placebo-controlled trials of the drug.

In a study led by Darius A. Paduch, MD, of New York-Presbyterian Hospital/Weill Cornell Medical College in New York, 66% of tadalafil-treated subjects who had severe ejaculatory dysfunction reported improved ejaculatory function compared with 36% who received placebo. In addition, 66% of tadalafil-treated patients with severe orgasmic dysfunction reported improvement compared with 35% of placebo recipients. Residual severe ejaculatory or orgasmic dysfunction after treatment had negative impacts on sexual satisfaction, the researchers reported in BJU International (2013;111:334-343).

In a press release, Dr. Paduch commented that up to 18% of men have a normal erection but do not ejaculate or take a long time to do so. According to Dr. Paduch, non-erectile sexual dysfunction is underreported and undertreated because of social stigma as well as misunderstanding about the physiology of male sexual response and orgasmic dysfunction.

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