Latest Secondary Hyperparathyroidism (SHPT) News
In a study, 94.1% of total PTx patients had improvement of bone mineral density at their most affected site.
Surgery decreased the risk of death from any cause by 32% compared with usual treatment.
Just 6.7% of patients had target levels of calcium, phosphorus, and parathyroid hormone a year after surgery.
More patients treated with MWA plus calcitriol reached iPTH levels below 150 pg/mL: 23.33% vs 8.54%.
Prior to starting therapy, parathyroid hormone trajectories show different patterns of increase and decrease.
Having 3 or 4 CKD-MBD markers in the danger zone more than doubled the chances of early death.
Calcitriol and paricalcitol raise levels of fibroblast growth factor 23 and sclerostin and lower levels of some bone turnover markers.
SHPT patients who received 6 months of cinacalcet treatment had a 10% increase in the odds of reaching target hemoglobin levels.
Spontaneous or no decline in parathyroid hormone is associated with higher mortality risk, study finds.
Randomized study compared total parathyroidectomy with and without autotransplantation.
Subtotal parathyroidectomy may lower the death risk of patients with secondary hyperparathyroidism and calciphylaxis.
Fracture incidence within a year of transplant was 3 times lower among patients who had surgery from 2009 to 2011 vs 2004 to 2006.
High individual biologic variability in PTH levels are among the factors that may make PTH unreliable as a biomarker of outcomes.
Bone turnover markers increased following unilateral nephrectomy.
Parathyroidectomy may improve leptin regulation and heart rate variability in SHPT patients.
NEPHROLOGY & UROLOGY NEWS
- Acute Kidney Injury (AKI)
- Chronic Kidney Disease (CKD)
- Contrast Nephropathy
- Cardiovascular Disease (CVD)
- Diabetic Nephropathy
- End-stage Renal Disease (ESRD)
- Lupus Nephritis
- Peritoneal Dialysis
- Secondary Hyperparathyroidism (SHPT)
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