BKV Infection Less Likely in Black Renal Transplant Recipients
DENVER—Black transplant patients may be a lower risk of BKV infection after transplantation than their white counterparts, according to a study.
Ankit Sakhuga, MD, and colleagues at the Medical College of Wisconsin in Milwaukee prospectively studied 189 renal transplant recipients. All subjects were screened for BKV DNA (blood and urine) at one, three, six, and 12 months after transplantation. The researchers defined BKV infection as the detection of BKV in plasma or urine. Of the 189 subjects, 65 (34%) had BKV infection. Forty-eight (25%) had both BK viremia and viruria.
In this group, 31 subjects were white, six were black, and 10 belong to another race. Seventeen patients (9%) had viruria alone; of these, 14 were white, two were black, and one was of another race. Donor demographics, donor source (living donor vs. deceased donor), kidney vs. kidney/pancreas transplant, delayed graft function, and acute rejection did not correlate with BKV infection. Neither did recipient age and gender and HLA mismatch.