Renal Cell Carcinoma

Combo Therapy Nonsuperior to Bevacizumab Monotherapy in RCC

Combo Therapy Nonsuperior to Bevacizumab Monotherapy in RCC

Bevacizumab, sorafenib, and temsirolimus combinations did not improve progression-free survival in renal cell carcinoma (RCC).

Factors Affecting Survival After Surgery for Locally Advanced RCC

Factors Affecting Survival After Surgery for Locally Advanced RCC

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Asymptomatic presentation, T3 low-grade tumors, and negative lymph nodes are associated with better progression-free and overall survival.

Urinary Cancers Not Linked to Lithium

Urinary Cancers Not Linked to Lithium

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Study findings contradict those of previous investigators.

Optimal RCC Tumor Shrinkage Threshold for Prognosis Should Be Lower

Optimal RCC Tumor Shrinkage Threshold for Prognosis Should Be Lower

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Data suggest that a 7% or 8% cut-off rather than the conventional 30% is a better predictor in patients treated for mRCC.

Early Tumor Shrinkage with TKIs Predicts mRCC Survival

Early Tumor Shrinkage with TKIs Predicts mRCC Survival

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RCC tumor shrinkage significantly and independently predicted overall survival.

Neoadjuvant Sunitinib Linked to Improved Outcomes in RCC with Thrombus

Neoadjuvant Sunitinib Linked to Improved Outcomes in RCC with Thrombus

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Neoadjuvant sunitinib was linked to primary tumor and thrombus shrinkage, reduced blood loss during surgery, as well as improved cancer-specific survival.

RCC Progression Rare After 10 Recurrence-Free Years Post-Nephrectomy

RCC Progression Rare After 10 Recurrence-Free Years Post-Nephrectomy

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Pathological stage was the only independent factor linked to kidney cancer progression.

Intensive Local Therapy to RCC Bone Metastases May Increase Survival

Intensive Local Therapy to RCC Bone Metastases May Increase Survival

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The approach was defined as surgical resection with a wide margin or radiotherapy with a biologically effective dose of 140 Gy or greater.

Metastasectomy May Up Survival in Metastatic RCC Patients

Metastasectomy May Up Survival in Metastatic RCC Patients

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In a study, patients who had the procedure had a better 5-year overall survival rate than those who did not (68% vs. 27%).

Larger RCC Tumors Predict High-Grade Pathology

Larger RCC Tumors Predict High-Grade Pathology

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New finding may inform treatment decisions.

Socioeconomic Predictors of Metastatic Clear-Cell RCC Identified

Socioeconomic Predictors of Metastatic Clear-Cell RCC Identified

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It is important to assess factors that may put patients at higher risk of metastatic disease, according to researchers.

Genetic Tests Should Include Normal and Cancerous Tissue

Genetic Tests Should Include Normal and Cancerous Tissue

Current practice of only focusing on tumor samples might adversely affect care.

Partial Nephrectomy Does Not Eliminate CKD Risk

Partial Nephrectomy Does Not Eliminate CKD Risk

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The risk is particularly elevated for patients who have CKD risk factors, such as hypertension, diabetes, and older age.

Urine Biomarkers May Diagnose Renal Cell Carcinoma

Urine Biomarkers May Diagnose Renal Cell Carcinoma

Urine aquaporin-1 and perilipin-2 may have utility as biomarkers for diagnosing malignant clear cell or papillary renal cell carcinoma (RCC).

Statins Promising for Cancers

Statins Promising for Cancers

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Studies suggest that these cholesterol-lowering drugs can improve treatment of genitourinary cancers and prevent contrast-induced nephropathy.

Risk Factors for Late RCC Recurrence Identified

Risk Factors for Late RCC Recurrence Identified

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Patients with these risk factors should be followed up for the rest of their lives, according to the researchers.

Statins May Prolong Life in Patients with Advanced Kidney Cancer

Statins May Prolong Life in Patients with Advanced Kidney Cancer

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In a study of 4,736 patients with metastatic renal cell carcinoma, use of the drugs was associated with a nearly 22% decreased risk of death.

Lycopene May Lower Kidney Cancer Risk in Older Women

Lycopene May Lower Kidney Cancer Risk in Older Women

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In a study of post-menopausal women, the highest quartile of lycopene intake was associated with a significant 39% decreased risk of renal cell carcinoma versus the lowest quartile.

Radiosurgery for Renal Tumors Shows Short-Term Efficacy

Radiosurgery for Renal Tumors Shows Short-Term Efficacy

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98% of the renal tumors were controlled at 9 months after treatment.

Partial Nephrectomy for Kidney Cancer Lowers ESRD Risk

Partial Nephrectomy for Kidney Cancer Lowers ESRD Risk

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Nephron-sparing approach is associated with a 56% decreased risk of postoperative end-stage renal disease versus radical surgery.

Poor Nutrition May Worsen Kidney Cancer Surgery Outcomes

Poor Nutrition May Worsen Kidney Cancer Surgery Outcomes

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Low serum albumin levels increase the risk of death in patients undergoing cytoreductive nephrectomy for metastatic renal cell carcinoma.

Everolimus Raises AKI Risk in Some Cancer Patients

Everolimus Raises AKI Risk in Some Cancer Patients

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Acute kidney injury developed in 23% of renal cell carcinoma patients receiving everolimus.

Statins May Improve Survival After Kidney Cancer Surgery

Statins May Improve Survival After Kidney Cancer Surgery

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New study links statin use with a 52% improvement in 3-year disease-specific survival.

Partial Nephrectomy Better for Certain Kidney Cancer Patients

Partial Nephrectomy Better for Certain Kidney Cancer Patients

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It preserves kidney function better than radical nephrectomy in patients with small- to medium-sized tumors, study finds.

Kidney Cancer Linked to Kidney Stones

Kidney Cancer Linked to Kidney Stones

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Meta-analysis reveals a significantly increased risk of kidney stones only in male patients with kidney cancer.

Kidney Cancer Death Risk Higher in Diabetics

Kidney Cancer Death Risk Higher in Diabetics

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Among surgically-treated renal cell carcinoma patients, diabetics have a 55% and 32% increased risk of cancer-specific and all-cause mortality.

Stopping Renal Cell Carcinoma (mRCC) Drugs Induces Tumor Flare

Stopping Renal Cell Carcinoma (mRCC) Drugs Induces Tumor Flare

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Study shows that tumor flare resulting from discontinuation of sunitinib and pazopanib is associated with decreased overall survival.

Post-Transplant Renal Cell Carcinoma Risk Factors Identified

Post-Transplant Renal Cell Carcinoma Risk Factors Identified

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Ultrasound surveillance for renal tumors should be performed on native and graft kidneys from 3 years after transplantation.

Are you more likely to perform partial rather than radical nephrectomy for tumors if robotic-assisted surgery is available?

Are you more likely to perform partial rather than radical nephrectomy for tumors if robotic-assisted surgery is available?

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Availability of robotic-assisted surgery at a hospital was independently associated with greater use of partial nephrectomy.

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