Radiofrequency Ablation, Partial Nephrectomy for RCC Offer Similar Long-Term Outcomes

Share this article:

In appropriately selected patients, radiofrequency ablation (RFA) is an effective minimally invasive treatment for cT1a renal cell carcinoma (RCC) that offers long-term oncologic outcomes comparable to nephron-sparing surgery, data show.

In a study of 74 patients with cT1a RCC—of whom 37 underwent RFA and 37 underwent partial nephrectomy (PN)—Jeffrey A. Cadeddu, MD, and colleagues at the University of Texas Southwestern Medical Center in Dallas compared five-year outcomes associated with the two treatments. Five-year overall survival with RFA and PN was 97.2% and 100%, respectively, according to a report in European Urology (published online ahead of print). Cancer-specific survival was 97.2% and 100%, disease-free survival was 89.2% and 89.2%, local recurrence-free survival was 91.7% and 94.6%, and metastasis-free survival was 97.2% and 91.8%. None of the differences between the groups was statistically significant.

The median follow-up was 6.5 years and 6.1 years for the RFA and PN groups, respectively. The RFA group was significantly older and had more advanced comorbidities than the PN group.

Share this article:
You must be a registered member of RUN to post a comment.

More in Kidney Cancer

Partial Nephrectomy More Likely If Robotic Systems Are Available

Partial Nephrectomy More Likely If Robotic Systems Are ...

Patients are 28% more likely to have partial nephrectomy at hospitals offering robotic-assisted surgery.

Kidney, Thyroid Cancers on the Rise in Children

Kidney, Thyroid Cancers on the Rise in Children

Study also finds increase in overall cancer rate among African-American children and adolescents.

Advanced Kidney Cancer Survival Rates Not Improved

Advanced Kidney Cancer Survival Rates Not Improved

The 3-year survival rates for patients diagnosed during 2006-2007 were similar to those diagnosed during 2001-2005.