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Prostate Cancer

PSA Screening Reduces Prostate Cancer Mortality, European Study Shows

John Schieszer May 24, 2012

The European Randomized Study of Screening for Prostate Cancer (ERSPC), which included 186,160 men, suggests that PSA screening can lower prostate cancer mortality rates.

New Assay Identifies Men Who May Be at Lower Risk for PCa Recurrence After Surgery

A recently approved diagnostic assay may improve clinicians' ability to predict a prostate cancer patient's risk of clinical recurrence after radical prostatectomy (RP), a company announced at the American Urological Association 2012 annual meeting.

Oral Drug Prolongs Survival in Men with Late-Stage PCa

Jody A. Charnow May 23, 2012

Enzalutamide, an investigational oral medication formerly known as MDV3100, prolongs survival by nearly five months in men with late-stage prostate cancer previously treated with docetaxel, according to data presented at the American Urological Association 2012 annual meeting.

Intermittent ADT May Offer Survival Edge in Advanced Prostate Cancer

Jody A. Charnow May 22, 2012

Intermittent androgen deprivation (IAD) therapy is associated with improved all-cause and prostate cancer (PCa)-specific mortality among elderly patients with advanced PCa, according to data presented at the American Urological Association 2012 annual meeting.

Durable Oncologic Outcomes Reported for RARP

Stephan Cho May 22, 2012

Robotic-assisted radical prostatectomy (RARP) is associated with long-term biochemical relapse-free survival, according to a study presented at the American Urological Association 2012 annual meeting.

Urologists Condemn Task Force's Anti-PSA Testing Stance

Jody A. Charnow May 22, 2012

The U.S. Preventive Services Task Force (USPSTF) on May 21 released its final recommendations on PSA-based screening for prostate cancer (PCa), which advises against the practice and gives it a grade D rating, meaning the task force believes there is "moderate or high certainty that the service has no net benefit or that the harms outweigh the benefit."

UTUC Tumor Location Affects Oncologic Outcomes

Jody A. Charnow May 21, 2012

Tumor location independently predicts cancer-specific survival (CSS) and recurrence-free survival (RFS) in patients with upper tract urothelial carcinoma (UTUC), researchers reported at the American Urological Association 2012 annual meeting.

Post-RP Survival Unaffected by Early Biochemical Recurrence

Jody A. Charnow May 21, 2012

Early biochemical recurrence after radical prostatectomy (RP) has no effect on survival among patients with low-risk prostate cancer (PCa), according to a study presented at the American Urological Association 2012 annual meeting.

HIFU Salvage Following EBRT Offers Good PCa Control

Jody A. Charnow May 21, 2012

High-intensity focused ultrasound (HIFU) provides shows promise as a salvage treatment option men with recurrent prostate cancer (PCa) following external beam radiotherapy (EBRT), data presented at the American Urological Association annual meeting suggest.

PCa-Specific Survival Can Be Good Even with Positive Nodes

Jody A. Charnow May 21, 2012

Prostate cancer (PCa) patients with lymph node positive disease found at radical prostatectomy (RP) can experience durable cancer-specific and metastases-free survival, researchers reported at the American Urological Association 2012 annual meeting.

Cure Possible Despite Positive Lymph Nodes

Jody A. Charnow May 21, 2012

Long-term PSA relapse-free survival after radical prostatectomy (RP) and pelvic lymph node dissection (PLND) is possible in a subset of patients with low volume nodal metastases, a researcher reported at the American Urological Association 2012 annual meeting.

Inappropriate Post-RP Medication Use Found

Jody A. Charnow May 20, 2012

A significant proportion of men take 5-alpha reductase inhibitors (5-ARIs) and alpha blockers following radical prostatectomy (RP) even though these medications have no proven role post-RP, according to study findings presented at the American Urological Association 2012 annual meeting.

Bladder Cancer More Likely with Radiotherapy

Jody A. Charnow May 20, 2012

Radiation therapy for prostate cancer (PCa) is associated with a greater likelihood of bladder cancer development compared with radical prostatectomy (RP), Japanese researchers reported at the American Urological Association 2012 annual meeting.

Findings Support Use of Salvage RALP

Jody A. Charnow May 20, 2012

Salvage robotic-assisted laparoscopic prostatectomy (RALP) for recurrent prostate cancer (PCa) appears to be safe and offers outcomes favorable to those of open salvage radical prostatectomy, investigators reported at the American Urological Association 2012 annual meeting.

Smokers Have Worse PCa Outcomes After EBRT

Jody A. Charnow May 20, 2012

Cigarette smoking is associated with an increased risk of prostate cancer (PCa) progression and genitourinary (GU) toxicities following treatment with external beam radiation therapy (EBRT), researchers reported at the American Urological Association 2012 annual meeting.

PCa Patient Survival Better with RP

Jody A. Charnow May 20, 2012

Radical prostatectomy (RP) is associated with better overall and disease-specific survival compared with external beam radiation therapy (EBRT) for localized prostate cancer (PCa), according to findings presented at the American Urological Association 2012 annual meeting.

Marriage Has a Positive Effect on Prostate Cancer Outcomes

Jody A. Charnow May 20, 2012

Being married is a plus when it comes to prostate cancer (PCa) outcomes, according to the findings of two studies presented at the American Urological Association 2012 annual meeting.

Circumcision May Lower Prostate Cancer Risk

John Schieszer May 17, 2012

Circumcision may help protect against prostate cancer, according to researchers in Seattle.

Optimal Sequencing of the New Prostate Cancer Drugs: An Interview with E. David Crawford, MD

Delicia Honen Yard May 15, 2012

Several new drugs have become available for treating advanced prostate cancer in the past year and a half. E. David Crawford, MD, head of urologic oncology at University of Colorado (UC) Hospital and an investigator at the UC Cancer Center, both in Aurora, and UC colleague Thomas W. Flaig, MD, recently published a review of these agents. Dr. Crawford talks to Renal & Urology News about the possible ways in which these drugs might be used.

Prostate Cancer Outcome Not Tied to Complementary Medicine

May 07, 2012

Although widely used, complementary and alternative medicine (CAM) does not impact patient satisfaction with treatment or patient-reported outcomes after treatment for localized prostate cancer.

Vitamin D May Help Prostate Cancer Patients

Rosemary Frei, MSc May 05, 2012

Small study shows benefit, but some experts urge caution.

Selected Prostate Cancer Patients May Benefit from HIFU

John Schieszer May 04, 2012

High intensity focused ultrasound (HIFU) may provide an alternative to traditional treatment for localized prostate cancer. British researchers report this use of ultrasound may be high beneficial in a select group of prostate cancer patients.

Prostate Imaging System Receives FDA Approval

Stephan Cho May 02, 2012

The device may improve clinicians' ability to diagnose prostate cancer.

Prostate Cancer Screening: Moving Beyond PSA

Robert G. Uzzo, MD, FACS May 01, 2012

More than 1 million prostate biopsies are performed annually in the United States, predominantly driven by elevations in PSA.

Radiotherapy Added to ADT Beneficial

Jody A. Charnow May 01, 2012

Adding radiotherapy to androgen deprivation therapy (ADT) improves outcomes in patients with locally advanced prostate cancer (PCa) and can be considered a standard treatment option.

After Radical Prostatectomy, Patient Learns He Never Had Prostate Cancer

Ann W. Latner, JD May 01, 2012

Dr. B, 57, was a urologist with a busy private practice. One of his patients was Mr. O, 69, who had an abnormal PSA result.

Circumcision May Reduce PCa Risk

Jody A. Charnow April 28, 2012

Recent population-based study findings indicate that circumcision before first sexual intercourse is associated with a reduction in the relative risk of prostate cancer (PCa).

New Urine-Based Assay Helps Determine Need for Repeat Biopsy

John Schieszer April 25, 2012

A newly approved prostate cancer gene 3 assay may help determine the need for repeat prostate biopsies in men who have had a previous negative biopsy.

Peripheral Androgen Blockade Feasible for PSA Relapse

Jody A. Charnow April 24, 2012

Peripheral androgen blockade with a combination of finasteride and flutamide is feasible for prostate cancer patients who experience biochemical failure after definitive local therapy, researchers reported online ahead of print in Cancer.