Prostate Cancer

Recent Developments in Prostate Cancer Management

Recent Developments in Prostate Cancer Management

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Interview with David F. Penson, MD.

Novel Technique May Improve Detection of Aggressive Prostate Cancer

Novel Technique May Improve Detection of Aggressive Prostate Cancer

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Small study demonstrates the promise of PET-CT using a radiotracer that targets the prostate-specific membrane antigen.

Preop ADT Could Potentially Eradicate High-Risk Prostate Tumors

Preop ADT Could Potentially Eradicate High-Risk Prostate Tumors

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No residual tumor was found in 5.4% of men who received androgen deprivation therapy prior to radical surgery for high-risk prostate cancer.

PCa Deaths Rare Among Low-Risk Patients on Active Surveillance

PCa Deaths Rare Among Low-Risk Patients on Active Surveillance

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Men receiving active surveillance were 24 times more likely to die from causes other than prostate cancer over 15 years.

Highest Prostate Cancer Death Rate Linked to Smallest Tumors

Highest Prostate Cancer Death Rate Linked to Smallest Tumors

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Association found in patients with lymph node involvement.

Early Chemotherapy Offers No Survival Edge in mCRPC

Early Chemotherapy Offers No Survival Edge in mCRPC

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Giving docetaxel before abiraterone does not improve progression-free and overall survival compared with the reverse sequence.

Prostate Cancer Diagnosis Raises Suicide Risk

Prostate Cancer Diagnosis Raises Suicide Risk

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Men with PCa have a 4-fold increased risk of suicidal death within 3 months of diagnosis compared to men who have other solid cancers.

Neutrophil Count May Predict Death Risk in Prostate Cancer Patients

Neutrophil Count May Predict Death Risk in Prostate Cancer Patients

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This laboratory measure could be useful in treatment decision algorithms.

MRI-TRUS Biopsy Aids Detection of Locally Recurrent PCa

MRI-TRUS Biopsy Aids Detection of Locally Recurrent PCa

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The technique, with cognitive assistance, identified recurrent tumors in 80% of patients.

Perineural Invasion Predicts Prostate Cancer Bone Metastasis

Perineural Invasion Predicts Prostate Cancer Bone Metastasis

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PNI in prostate biopsy specimens are associated with an 11-fold increased risk of bone metastasis.

Acupuncture May Ease Hot Flashes from Androgen Deprivation Therapy

Acupuncture May Ease Hot Flashes from Androgen Deprivation Therapy

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Acupuncture's ability to stimulate endorphin production may partly explain the clinical improvements.

Transperineal Prostate Biopsy Better for PCa Risk Statification

Transperineal Prostate Biopsy Better for PCa Risk Statification

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It more accurately predicted the actual clinical risk category at final pathology compared with transrectal ultrasonography-guided biopsy.

Biomarkers May Predict Aggressive Prostate Cancer in Black Men

Biomarkers May Predict Aggressive Prostate Cancer in Black Men

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A set of genes may identify a prostate cancer subtype in African American patients that needs aggressive treatment.

Spousal Relationship Impacted by Prostatectomy

Spousal Relationship Impacted by Prostatectomy

Surgery for prostate cancer may affect relationship satisfaction among couples, which may ultimately disrupt recovery.

Close Surgical Margins Raise Risk of Prostate Cancer Return

Close Surgical Margins Raise Risk of Prostate Cancer Return

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The biochemical recurrence rate after radical prostatectomy is similar to that associated with positive surgical margins.

Robotic Prostate Surgery Preserves Erectile Function Better

Robotic Prostate Surgery Preserves Erectile Function Better

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Compared with laparoscopic radical prostatectomy, robotic-assisted laparoscopic prostatectomy is associated with a 51% increased likelihood of return of erectile function.

ADT Plus Docetaxel Chemo May Increase Survival in Metastatic Prostate Cancer

ADT Plus Docetaxel Chemo May Increase Survival in Metastatic Prostate Cancer

Adding chemotherapy to hormone therapy added 14 months to patients' lives in study.

NLR Predicts GU Cancer Outcomes After Treatment

NLR Predicts GU Cancer Outcomes After Treatment

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New data suggest a prognosis role for the neutrophil to lymphocyte ratio.

Predictors of Incidental Prostate Cancer After HoLEP Identified

Predictors of Incidental Prostate Cancer After HoLEP Identified

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In a study, only older age and greater total PSA density were independently associated with an increased risk of a PCa diagnosis.

Cancer Trials Should Involve More Seniors, ASCO Says

Cancer Trials Should Involve More Seniors, ASCO Says

Older adults react differently to treatment, oncology group notes.

Androgen Deprivation for Localized Prostate Cancer Ups Cardiac Risks

Androgen Deprivation for Localized Prostate Cancer Ups Cardiac Risks

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Patients with longer life expectancy are most at risk of cardiac morbidity, researchers concluded.

High-Grade Prostate Cancer Linked to Low Testosterone

High-Grade Prostate Cancer Linked to Low Testosterone

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Hypogonadal men are more likely than those with normal testosterone to have prostate biopsy results showing high-grade PCa.

Some Hypogonadism Guidelines Need Updating, Review Finds

Some Hypogonadism Guidelines Need Updating, Review Finds

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Quality studies are still needed to answer crucial questions about TRT and prostate cancer, cardiovascular risk.

Many Cancer Patients Unaware of Ways to Preserve Fertility

Many Cancer Patients Unaware of Ways to Preserve Fertility

Almost 1 in 3 not told cancer treatment might affect future fertility.

Black Men Twice as Likely to Die of Prostate Cancer

Black Men Twice as Likely to Die of Prostate Cancer

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Study in England shows that that 1 in 12 black men die from the malignancy compared with 1 in 24 white men.

Erectile Function Worsens In Most Men After Prostate Biopsy

Erectile Function Worsens In Most Men After Prostate Biopsy

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Results of a prospective study have implications for patient counseling.

Chemo Doesn't Improve Quality of Life in End-Stage Cancer

Chemo Doesn't Improve Quality of Life in End-Stage Cancer

No improvement in quality of life, even for patients with good baseline performance status.

Biomarkers Help Distinguish Prostate Cancer from Prostatitis

Biomarkers Help Distinguish Prostate Cancer from Prostatitis

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The biomarkers PHI and PCA3 demonstrated high diagnostic accuracy in discriminating prostate cancer from prostatitis in re-biopsy candidates.

Statin Use Fails To Prevent Progression to Lethal Prostate Cancer

Statin Use Fails To Prevent Progression to Lethal Prostate Cancer

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Statin use following diagnosis of localized PCa does not significantly reduce the risk of metastasis or death from PCa.

Gleason Score Predicts BCR in High-Risk Prostate Cancer Patients

Gleason Score Predicts BCR in High-Risk Prostate Cancer Patients

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The finding is based on a study of men who underwent radical surgery for pT3aN0/NxR1 tumors but received no adjuvant or neoadjuvant therapy.

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