Prostate Cancer

Prostatitis Found to Increase Prostate Cancer Risk

Prostatitis Found to Increase Prostate Cancer Risk

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Researchers observe no association between prostate cancer and urethritis, orchitis, or epididymitis.

Complications More Likely After Radiotherapy vs. Surgery for PCa

Complications More Likely After Radiotherapy vs. Surgery for PCa

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Radiation treatment is associated with an increased risk of requiring minimally invasive urologic procedures.

Enzalutamide Superior to Bicalutamide for mCRPC

Enzalutamide Superior to Bicalutamide for mCRPC

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In a phase 2 trial, enzalutamide treatment was associated with significantly longer progression-free survival.

Prostate Cancer-specific Comorbidity Index Stratifies Mortality Risk

Prostate Cancer-specific Comorbidity Index Stratifies Mortality Risk

Age-adjusted prostate cancer-specific comorbidity index strongly predictive of other-cause mortality.

Genomic Prostate Score Predicts PCa Recurrence, Adverse Pathology

Genomic Prostate Score Predicts PCa Recurrence, Adverse Pathology

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Each 20-unit increment in GPS was associated with a more than 2-fold increased likelihood of recurrence.

Weekend Hospitalizations Worsen Outcomes for Metastatic PCa Patients

Weekend Hospitalizations Worsen Outcomes for Metastatic PCa Patients

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They are more likely to die and suffer complications compared with those admitted on weekdays.

Palliative Radiation May Ease Pelvic Tumor Symptoms in CRPC Patients

Palliative Radiation May Ease Pelvic Tumor Symptoms in CRPC Patients

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The treatment was most effective in relief of macroscopic hematuria.

Prostate Cancer Treatment May Increase Colorectal Cancer Risk

Prostate Cancer Treatment May Increase Colorectal Cancer Risk

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Researchers observed greater incidences of colorectal cancer among patients who underwent bilateral orchiectomy, surgery, and ADT.

Prostate Health Index Predicts Post-RARP Prostate Cancer Recurrence

Prostate Health Index Predicts Post-RARP Prostate Cancer Recurrence

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A PHI of 82 discriminated between patients with and without biochemical recurrence.

Distress Factors in Newly Diagnosed PCa Patients Identified

Distress Factors in Newly Diagnosed PCa Patients Identified

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Factors include younger age, aggressive disease, and concern that their malignancy is uncontrollable.

Smoking Increases Risk of Prostate Cancer Recurrence After Surgery

Smoking Increases Risk of Prostate Cancer Recurrence After Surgery

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Smoking cessation for 10 or more years, however, mitigates that risk.

AR-V7 Positive PCa Patients Remain Sensitive to Taxane Chemo

AR-V7 Positive PCa Patients Remain Sensitive to Taxane Chemo

Androgen receptor splice variant 7 (AR-V7) detection may serve as treatment biomarker in castration-resistant prostate cancer (CRPC).

Androgen Deprivation Therapy Increases Metabolic Syndrome

Androgen Deprivation Therapy Increases Metabolic Syndrome

Researchers observed increases in components of metabolic syndrome and in the prevalence of full metabolic syndrome among men with prostate cancer treated with ADT.

Western Diet Increases Mortality in PCa Patients

Western Diet Increases Mortality in PCa Patients

Men most wedded to a "western" diet of red and processed meat and refined grains were more than two-and-a-half-times more likely to die from a prostate cancer-related cause.

Prostate Cancer Death Risk Lowered by Statin-Metformin Combo

Prostate Cancer Death Risk Lowered by Statin-Metformin Combo

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In a study of high-risk PCa patients, the statin-metformin combo was associated with a 43% reduction in risk compared with non-use of the medications.

Androgen Deprivation Therapy Increases Diabetes Risk

Androgen Deprivation Therapy Increases Diabetes Risk

Findings among men treated for localized prostate cancer.

Cancer Patients Would Pay for Tumor Genetic Profiling

Cancer Patients Would Pay for Tumor Genetic Profiling

Two-thirds of patients feel that tumor profiling could improve their treatment; many will pay out of pocket.

Short-Term Androgen Deprivation Plus Radiation Superior

Short-Term Androgen Deprivation Plus Radiation Superior

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The combination improved oncologic control better than dose-escalated radiotherapy alone in men with intermediate-risk prostate cancer.

ADT Therapy for Prostate Cancer Linked to Impaired Thinking

ADT Therapy for Prostate Cancer Linked to Impaired Thinking

Men with a particular gene mutation affected most, researchers find.

PCPs Screening Less with PSA Per USPSTF Recs

PCPs Screening Less with PSA Per USPSTF Recs

Primary care screening patterns have changed as a result of the USPSTF recommendation.

Salvage Cryo Outcomes Similar After EBRT, Brachytherapy

Salvage Cryo Outcomes Similar After EBRT, Brachytherapy

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Study reveals comparable rates of freedom from biochemical failure at 5 years.

Early ADT for Recurrent Prostate Cancer May Hike Death Risk

Early ADT for Recurrent Prostate Cancer May Hike Death Risk

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This effect appears to occur mainly in men who experience recurrence when they are younger than 65 and in those with low-risk cancer.

DRE Has Limited Value for Prostate Cancer Screening

DRE Has Limited Value for Prostate Cancer Screening

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Biopsies triggered by an abnormal DRE alone were significantly less likely to detect clinically significant prostate cancer than biopsies triggered by an abnormal PSA alone.

Post-RP Outcomes Differ for Gleason 8, 9-10 Prostate Cancer

Post-RP Outcomes Differ for Gleason 8, 9-10 Prostate Cancer

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Gleason 9-10 tumors are associated with a greater risk of biochemical and clinical recurrence, but not overall survival.

Radical Prostatectomy Offers Excellent Long-Term Outcomes

Radical Prostatectomy Offers Excellent Long-Term Outcomes

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Researchers report on a study in which survivors were followed up for a median of 14 years.

Surgical Margin Status Has No Effect on PCa Patient Survival

Surgical Margin Status Has No Effect on PCa Patient Survival

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Researchers concluded that margin status is a surrogate for established risk criteria.

Elevated NLR Linked to Worse Post-RP Outcomes

Elevated NLR Linked to Worse Post-RP Outcomes

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Neutrophil-lymphocyte ratio could have a prognostic role in localized prostate cancer.

RALP Offers Favorable Long-Term Prostate Cancer Control

RALP Offers Favorable Long-Term Prostate Cancer Control

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The 10-year rates of biochemical and clinical recurrence are comparable to those of open surgery.

PCa Metastasis Predictors in Active Surveillance Patients ID'd

PCa Metastasis Predictors in Active Surveillance Patients ID'd

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A PSA doubling time of less than 3 years and a Gleason score of 8-10 were associated with an increased risk of metastasis.

PCa Active Surveillance Widely Used by Community Urologists

PCa Active Surveillance Widely Used by Community Urologists

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Recent study shows that 71% of prostate cancer patients with very-low-risk disease were placed on active surveillance.

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