Prostate Cancer

Prostate Cancer Gene Testing Guidelines Issued

Prostate Cancer Gene Testing Guidelines Issued

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Clinicians need to ask about cancers among members of the maternal and paternal sides of a family.

Routine Office Urine Culture Before Prostate Biopsy Is Unnecessary

Routine Office Urine Culture Before Prostate Biopsy Is Unnecessary

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In a single center study, asymptomatic bacteriuria resolved before prostate biopsy, without additional treatment.

Polygenic Hazard Score Predicts Age of Prostate Cancer Diagnosis

Polygenic Hazard Score Predicts Age of Prostate Cancer Diagnosis

Polygenic hazard score can guide screening based off predicted prostate cancer diagnosis age.

PSA at 7 Months Prognostic in Treated mHSPC

PSA at 7 Months Prognostic in Treated mHSPC

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A study showed longer survival among patients with metastatic hormone-sensitive prostate cancer who achieved a PSA level of 0.2 ng/mL or less 7 months after initiating ADT.

Mediterranean Diet Best for Lowering Aggressive Prostate Cancer Risk

Mediterranean Diet Best for Lowering Aggressive Prostate Cancer Risk

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Study finds that closely adhering to a Mediterranean-style diet possibly protects men from aggressive and advanced prostate cancer.

High-grade Prostate Cancer Risk Again Linked to Cholesterol

High-grade Prostate Cancer Risk Again Linked to Cholesterol

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Each 10 mg/dL increase in serum levels of total and HDL cholesterol are associated with a significant 5% and 14% increased risk of high-grade PCa, respectively.

Is It Safe to Avoid Biopsy in Men With Elevated PSA?

Is It Safe to Avoid Biopsy in Men With Elevated PSA?

Multiparametric magnetic resonance imaging in conjunction with transrectal ultrasound-guided biopsy improves discrimination between clinically significant and insignificant prostate tumors and can spare patients unnecessary biopsies.

Prostate Cancer Surgery Complications More Likely Among Older Men

Prostate Cancer Surgery Complications More Likely Among Older Men

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Patient age 70 years and above is an independent risk factor for perioperative morbidity, according to data from a national cohort.

Novel 3D Printed Prostates Could Improve Preoperative Planning

Novel 3D Printed Prostates Could Improve Preoperative Planning

New technique uses silicone-based polymer inks to create prostate models with the tactile sensation, pliability, and texture of a real prostate.

Odds of Prostate Cancer Treatment With SBRT Linked to Travel Distance

Odds of Prostate Cancer Treatment With SBRT Linked to Travel Distance

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Patients who have to travel longer distances for prostate cancer treatment are more likely to receive stereotactic body radiotherapy.

Repeat Prostate Biopsies Do Not Raise Risk of Post-RP Complications

Repeat Prostate Biopsies Do Not Raise Risk of Post-RP Complications

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Rates of erectile dysfunction and urinary incontinence at 1, 2, and 3 years after radical surgery are not higher among men who have multiple prostate biopsies while on active surveillance for prostate cancer.

Shift Workers at Higher Risk for Prostate Cancer

Shift Workers at Higher Risk for Prostate Cancer

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A rotating shift schedule appeared the most risky.

Optimal Salvage Treatment for Radiorecurrent PCa Still Unclear

Optimal Salvage Treatment for Radiorecurrent PCa Still Unclear

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Definitive comparative effectiveness data are lacking for salvage prostatectomy or salvage cryotherapy.

Smaller Difference in Prostate Cancer Death Risk Found Between RT, RP

Smaller Difference in Prostate Cancer Death Risk Found Between RT, RP

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Among patients with high-risk prostate cancer, investigators observe no significant difference in cancer-related death risk between radiotherapy and radical prostatectomy.

High Intakes of Teas, Peas, Soybeans May Increase Prostate Cancer Risk

High Intakes of Teas, Peas, Soybeans May Increase Prostate Cancer Risk

An analysis of an intervention arm of the PLCO Cancer Screening Trial evaluated the risk of prostate cancer relative to dietary consumption of isoflavones, a dietary compound found in some plant foods.

Enzalutamide Does Not Appear to Up Seizures in mCRPC

Enzalutamide Does Not Appear to Up Seizures in mCRPC

Male patients with mCRPC and seizure risk factors did not have increased seizure incidents when taking Enzalutamide.

Severe Acne May Boost Prostate Cancer Risk

Severe Acne May Boost Prostate Cancer Risk

Recent research suggests that P. acnes, which is associated with acne vulgaris, is more likely to be present in the prostatic tissue of patients with the disease than in healthy individuals.

MRI Predicts Outcomes of Prostate Cancer Salvage Radiotherapy

MRI Predicts Outcomes of Prostate Cancer Salvage Radiotherapy

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A negative mpMRI is associated with a higher risk for PSA recurrence and metastasis following salvage radiotherapy for recurrent prostate cancer after radical prostatectomy.

Cancer Pts With Private Insurance, Medicare May Have Survival Advantage

Cancer Pts With Private Insurance, Medicare May Have Survival Advantage

Cancer survival was greatly skewed toward patients with Medicare or private insurance.

Structured Investigation of Outpatient Transperineal Prostate Biopsy

Structured Investigation of Outpatient Transperineal Prostate Biopsy

The transperineal approach to prostate biopsy has recently been adopted at many centers as an alternative to TRUS-B.

Less Frequent Biopsies May Be Appropriate for PCa Active Surveillance

Less Frequent Biopsies May Be Appropriate for PCa Active Surveillance

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Investigators who compared 4 active surveillance cohorts found that biennial prostate biopsies appear to be an acceptable alternative to annual biopsies.

Prostate Health Index Shown to Decrease Number of Prostate Biopsies

Prostate Health Index Shown to Decrease Number of Prostate Biopsies

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Results of a large prospective study show that appropriate use of the phi test can improve physicians' ability to diagnose and manage patients.

PET/CT Imaging Phenotype Tied With Survival in mCRPC

PET/CT Imaging Phenotype Tied With Survival in mCRPC

Assessments of androgen receptor, glycolysis prognostic in castration-resistant prostate cancer.

Testosterone Therapy May Lower Prostate Cancer Incidence

Testosterone Therapy May Lower Prostate Cancer Incidence

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Hypogonadal men who received testosterone replacement therapy had a lower incidence of prostate cancer than those who did not, and their cancers were less severe.

PET/CT for Prostate Cancer: From Diagnosis to Metastasis

PET/CT for Prostate Cancer: From Diagnosis to Metastasis

Novel PET radiotracers have shown great potential in the early diagnosis and staging of PCa, detection of post-treatment recurrence, and monitoring of metastases not previously possible with current imaging technologies.

Surgery vs Radiation for High-Risk Prostate Cancer

Surgery vs Radiation for High-Risk Prostate Cancer

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Physicians who treat patients with high-risk prostate cancer remain uncertain as to the optimal treatment approach, in part due to difficulty in interpreting study data.

Second-Line Enzalutamide May Benefit Some mCRPC Patients

Second-Line Enzalutamide May Benefit Some mCRPC Patients

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In a prospective study, mCRPC patients placed on enzalutamide after their disease progressed while on abiraterone therapy had a median radiographic progression-free survival of 8.1 months.

Active Surveillance Required After Prostate Cancer Focal Ablation

Active Surveillance Required After Prostate Cancer Focal Ablation

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In a small but meaningful number of patients, Gleason pattern 4 disease missed by MRI and systematic biopsy is present outside the focal ablation zone.

Genetic Variant Predicts Faster Time to Prostate Cancer Metastasis

Genetic Variant Predicts Faster Time to Prostate Cancer Metastasis

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The variant HSD3B1 allele increases the likelihood of metastasis in men receiving androgen-deprivation therapy for biochemically recurrent disease after radiotherapy for localized PCa.

Men With PCa Most Likely to Die From Other Causes

Men With PCa Most Likely to Die From Other Causes

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Non-metastatic prostate cancer patients are more likely to die from causes other than the disease.

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