The six-month cumulative incidence of myocardial infarction was 2.0% and 0.7% in patients with cancer and controls, respectively.
Prostate cancer patients accurately report their comorbidities, and participants in cancer clinical trials report more adverse events than trial investigators.
Improvement in BMD was seen with denosumab, which also reduced the incidence of new radiographic vertebral fractures in one high-quality trial.
Men with 1 high-risk factor experience better outcomes following treatment than those with 2 or 3 high-risk factors, study finds.
Study of men with intermediate- or high-risk prostate cancer finds facility-level racial disparity in use of definitive treatment.
A detectable PSA nadir combined with shorter time to nadir after prostate cancer surgery is associated with a higher risk of biochemical recurrence.
63% of patients were managed initially with observation.
Nearly 1 in 3 patients diagnosed with Gleason 3+4 favorable intermediate-risk prostate cancer had their disease upgraded or upstaged at radical prostatectomy.
Most common infection in prostate biopsy was E. coli, followed by mild bleeding.
Throughout the study, a total of 115 lobes were treated and 82% achieved absent clinically significant cancer.
Researchers calculated that the absolute increase in lifetime risk of prostate cancer associated with vasectomy was just 0.6%.
Study reveals that a quarter of men with low-volume intermediate-risk prostate cancer had adverse pathologic features found at radical prostatectomy.
Every additional 4 inches of height was associated with a 21% increase in risk of being diagnosed with high-grade prostate cancer, and a 17% increased risk of dying from prostate cancer.
Randomized trial found no significant difference in all-cause and cancer-specific survival between radical prostatectomy and observation for localized prostate cancer.
Across time, only African-American race correlated with greater regret.
Men with prostate cancer and at least one additional primary cancer are enriched for harboring a germline deleterious mutation in a cancer-predisposing gene.
Over a 10-year period, radical prostatectomy use increased steadily while radiotherapy use declined
Both findings on biopsy also predict a lower odds of high-grade cancer.
Prostate cancer patients on active surveillance who have no cancer found on confirmatory biopsy have a reduced risk of grade and volume reclassification.
Over 15 years of follow-up, considerable proportion of men undergo prostate-specific antigen testing
No added benefit was seen with the addition of biomarkers for African-American men.
New findings suggest that clinicians consider the pathologic characteristics of the primary tumor as well as the burden of LN metastases when deciding on management, investigators say.
Radiotherapy for prostate cancer patients with persistently elevated PSA after radical surgery improved survival only among those with worse pathologic characteristics.
Routine prostate cancer screenings can be done as long as the patient makes the decision after a physician consultation.
High-income counties had far higher diagnosis rates for the four cancers than low-income counties, but the combined mortality rate was similar for both.
The researchers found that the median overall survival was 31.2 and 26.0 months in the PRO and usual care groups, respectively.
Some men who undergo multigene testing for inherited prostate cancer misinterpret findings of variants of uncertain significance.
Younger patients who chose surgery vs radiation for initial treatment had a 48% survival advantage.
Extended pelvic lymph node dissection versus limited dissection during radical prostatectomy does not improve biochemical recurrence rates.
CBP was associated with a reduction in sperm concentration, sperm vitality, sperm total and progressive motility.
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