Prostate Cancer

Study: mpMRI Findings in Prostate Cancer Patients Unaffected by TRT

Study: mpMRI Findings in Prostate Cancer Patients Unaffected by TRT

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Results show that mpMRI and PI-RADSv2 score have a greater ability to detect prostate cancer progression after TRT compared with PSA.

No Survival Benefit for EBT With Brachytherapy in Intermediate PCa

No Survival Benefit for EBT With Brachytherapy in Intermediate PCa

Addition of external beam therapy doesn't improve 5-year progression-free survival in prostate cancet

Hypertension May Raise Prostate Cancer Risk

Hypertension May Raise Prostate Cancer Risk

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Data from 21 observational studies showed an 8% increased risk of prostate cancer.

Progress to More Nuanced Medicine

Progress to More Nuanced Medicine

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Medicine is making progress to refine patient care.

MRI/US Fusion Improves Prostate Cancer Detection

MRI/US Fusion Improves Prostate Cancer Detection

The approach can help identify suitable candidates for active surveillance, but false positives and cost effectiveness are concerns.

10-Year Mortality for Localized PCa Does Not Differ by Treatment Choice

10-Year Mortality for Localized PCa Does Not Differ by Treatment Choice

Ten-year mortality rates of prostate cancer are low, regardless of whether patients are treated with radiotherapy, surgery, or undergo only active surveillance.

Digital Rectal Examination, PSA Testing Rates Declining

Digital Rectal Examination, PSA Testing Rates Declining

Decreases in use of screening following USPSTF recommendations against routine PSA screening.

Vasectomy Unlikely to Increase Prostate Cancer Risk, Mortality

Vasectomy Unlikely to Increase Prostate Cancer Risk, Mortality

Large study challenges previous research linking the procedure to slightly higher chance of disease.

Urinary, Sexual Function Recovery Differs by Localized PCa Treatment

Urinary, Sexual Function Recovery Differs by Localized PCa Treatment

Urinary, bowel, sexual function, and quality of life among men with prostate cancer may vary depending on treatment type.

Latest Assays Can Improve Prostate Cancer Workup

Latest Assays Can Improve Prostate Cancer Workup

Clinicians now have tools for improving prostate cancer screening and risk stratification.

Bacteremia Often Caused by TURP

Bacteremia Often Caused by TURP

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Researchers' results showed that the presence of a urinary catheter and recent antibiotic use were associated with increased odds of intra-operative bacteremia.

Adding Zoledronic Acid to ADT Does Not Delay PCa Treatment Failure

Adding Zoledronic Acid to ADT Does Not Delay PCa Treatment Failure

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Study tested the combination in men with treatment-naïve prostate cancer and bone metastasis.

PSA Failure Predicts Death in Men With Low Comorbidity Burden

PSA Failure Predicts Death in Men With Low Comorbidity Burden

Findings among men with localized intermediate- and high-risk prostate cancer.

Metastatic PCa Is On the Rise

Metastatic PCa Is On the Rise

Between 2007 to 2013, the incidence of metastatic PCa increased by 7.1% annually.

PCa Treatment Can Relieve Pre-Existing LUTS

PCa Treatment Can Relieve Pre-Existing LUTS

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Patients' pre-existing urinary problems influenced their perceptions of symptom relief after prostate cancer treatment.

Long-term ADT Use Not Linked With Cognitive Decline

Long-term ADT Use Not Linked With Cognitive Decline

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Ongoing use of androgen-deprivation therapy (ADT) for up to 36 months is not associated with cognitive decline among men with prostate cancer.

Genetic Variant in Prostate Cancer Patients May Predict ADT Failure

Genetic Variant in Prostate Cancer Patients May Predict ADT Failure

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Men with 1 or 2 copies of the HSD3B1 (1245C) allele are more likely to experience disease progression.

Treatment-Related Hospitalizations Similar for PCa Surgery, Radiation

Treatment-Related Hospitalizations Similar for PCa Surgery, Radiation

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The odds were 16% lower for men who underwent external beam radiotherapy/intensity modulated radiation therapy, however.

Prostate Cancer Death Rate Higher Among Blacks in Most Big Cities

Prostate Cancer Death Rate Higher Among Blacks in Most Big Cities

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Greatest racial disparity found in Los Angeles, the least in Minneapolis.

High-Risk PCa Found in Black Men Initially on Active Surveillance

High-Risk PCa Found in Black Men Initially on Active Surveillance

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Even black men with relatively few comorbidities had increased risks of upgrading or upstaging compared with non-black patients.

Fewer Early PCa Diagnoses Following USPSTF Recs

Fewer Early PCa Diagnoses Following USPSTF Recs

Early prostate cancer diagnosis rates fell, while cases of advanced prostate cancer remained stable.

Treatment Regret Infrequent After Radical Prostatectomy, IMRT

Treatment Regret Infrequent After Radical Prostatectomy, IMRT

Overall decision regret for 16.9% of patients; more regret for RP than radiotherapy component.

Radium-223 With Concomitant Therapy May Prolong Life With mCRPC

Radium-223 With Concomitant Therapy May Prolong Life With mCRPC

Survival was longer in patients who received radium-223 plus abiraterone, enzalutamide, or both.

High-Grade Prostate Cancer Linked to Diabetes Drugs

High-Grade Prostate Cancer Linked to Diabetes Drugs

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Men who used the medications prior to radical prostatectomy had 83% greater odds of Gleason 7-10 tumors compared with non-users.

Radical Local Therapy Offers Mortality Benefit in Very High-Risk PCa

Radical Local Therapy Offers Mortality Benefit in Very High-Risk PCa

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Prostatectomy and radiotherapy with or without ADT reduced prostate cancer-specific and all-cause mortality rates.

Adjuvant ADT May Up Mortality in Black Prostate Cancer Patients

Adjuvant ADT May Up Mortality in Black Prostate Cancer Patients

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Androgen deprivation increased all-cause mortality risk by 77% among black men who underwent brachytherapy for favorable-risk prostate cancer.

Selenium May Cut Aggressive Prostate Cancer Risk

Selenium May Cut Aggressive Prostate Cancer Risk

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An analysis of individual participant data from 15 prospective studies suggests a protective effect.

ED Drugs May Not Reduce Prostate Cancer Risk

ED Drugs May Not Reduce Prostate Cancer Risk

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Prostate cancer was diagnosed in 19.5% of PDE5i users vs 22.7% of nonusers, a statistically insignificant difference.

Skeletal-Related Events Predict Higher Mortality in mCRPC

Skeletal-Related Events Predict Higher Mortality in mCRPC

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Skeletal-related events occurred in 38% of patients with metastatic castration-resistant prostate cancer.

Intestinal Autoimmunity Possibly Linked to ADT

Intestinal Autoimmunity Possibly Linked to ADT

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ADT for prostate cancer may be associated with a reduced risk of inflammatory bowel disease.

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