Prostate Cancer

Detection Down for Prostate Cancer, Up for Other Cancers Since ACA

Detection Down for Prostate Cancer, Up for Other Cancers Since ACA

The investigators found that the percentage of patients diagnosed with stage I cancer increased significantly from 2013 to 2014 after the ACA was implemented.

Prostate Cancer Subtypes Differ in ADT Response After Surgery

Prostate Cancer Subtypes Differ in ADT Response After Surgery

Only luminal B prostate cancers were significantly associated with postoperative response to ADT in a subset analysis in retrospective cohorts.

PCa Active Surveillance Safe, Effective for Younger Patients

PCa Active Surveillance Safe, Effective for Younger Patients

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A majority of active surveillance patients under age 60 did not progress to definitive prostate cancer treatment.

MRI-Fusion Biopsy Benefits PCa Active Surveillance Patients

MRI-Fusion Biopsy Benefits PCa Active Surveillance Patients

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Targeting PI-RADS 4 and 5 lesions for confirmatory biopsy improves detection of clinically significant cancer.

Sipuleucel-T Survival Benefit Greater in Blacks

Sipuleucel-T Survival Benefit Greater in Blacks

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Median overall survival was 9.3 months longer for black versus white patients with metastatic castration-resistant prostate cancer.

Fusion Biopsy Ups Detection of Clinically Significant PCa

Fusion Biopsy Ups Detection of Clinically Significant PCa

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Fusion biopsy has improved over the last decade and increasingly detects clinically significant prostate cancer, according to data trends from one institution.

Prostate Cancer Distant Metastasis Predicted by APV

Prostate Cancer Distant Metastasis Predicted by APV

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Highest quartile of alkaline phosphatase velocity in men who experience biochemical recurrence after radical prostatectomy is associated with 2-fold higher risk.

Non-index Lesions at Biopsy Help Predict Adverse RP Outcomes

Non-index Lesions at Biopsy Help Predict Adverse RP Outcomes

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Systematic biopsy parameters identified patients at higher risk of positive surgical margins.

HoLEP Feasible for BPH Patients With Low-risk Prostate Cancer

HoLEP Feasible for BPH Patients With Low-risk Prostate Cancer

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The laser procedure was successful for 7 selected patients with enlarged prostates and LUTS harboring low-risk prostate cancer.

New Risk Models May Reduce Unnecessary Prostate Biopsies

New Risk Models May Reduce Unnecessary Prostate Biopsies

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The new risk models improve upon PI-RADS version 1.0 and ERPSC risk calculators used for prostate biopsy decisions.

New Nomogram Improves Post-RP Metastasis Predictions

New Nomogram Improves Post-RP Metastasis Predictions

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Nomogram based on a cohort of men with high-risk prostate cancer is more accurate than the CAPRA and MSKCC nomograms, researchers report.

Bone Metastasis At Diagnosis Predicts Early Prostate Cancer Mortality

Bone Metastasis At Diagnosis Predicts Early Prostate Cancer Mortality

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Men who present with prostate cancer bone metastasis and no visceral metastases have a median survival time of 37 months, study finds.

Cholesterol Linked to High-Grade Prostate Cancer

Cholesterol Linked to High-Grade Prostate Cancer

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Each 10 mg/dL increase in total cholesterol is associated with a significant 23% greater odds of high-grade prostate cancer.

Biopsy Timing in Active Surveillance Not Tied to PCa Reclassification

Biopsy Timing in Active Surveillance Not Tied to PCa Reclassification

But PSA density and body mass index are associated with prostate cancer reclassification.

Yoga May Relieve Symptoms of Prostate Cancer Radiation Tx

Yoga May Relieve Symptoms of Prostate Cancer Radiation Tx

Men who attended yoga classes had less fatigue and better sexual and urinary function than those in the comparison group.

PSA Surge With Abiraterone Has No Long-Term Impact on Outcome

PSA Surge With Abiraterone Has No Long-Term Impact on Outcome

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Spike in PSA level after starting abiraterone does not affect progression-free or overall survival, study finds.

More Preclinical PCa, Progression Among Black Men

More Preclinical PCa, Progression Among Black Men

Also increased risk of progression to metastatic disease compared with the general population.

Metformin Plus Chemo Does Not Up mCRPC Survival

Metformin Plus Chemo Does Not Up mCRPC Survival

Survival curves showed that metformin use with docetaxel did not improve prostate cancer specific survival or overall survival.

USPSTF Issues Draft PCa Screening Recommendations

USPSTF Issues Draft PCa Screening Recommendations

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The US Preventive Services Task Force now suggests decisions about PSA testing should be made on an individual basis for men aged 55 to 69.

PSA Doubling Time Predicts Metastasis, Mortality Risks in CRPC

PSA Doubling Time Predicts Metastasis, Mortality Risks in CRPC

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Study identifies PSADT cut-points that can aid in risk stratification of men with non-metastatic castration-resistant prostate cancer.

Prostate Cancer Risk Lower in Black Men With High VDBP

Prostate Cancer Risk Lower in Black Men With High VDBP

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Highest vs lowest quartile of vitamin D binding protein associated with 55% lower odds of prostate cancer.

Prostate Cancer Progression Risk in AS Not Linked to Family History

Prostate Cancer Progression Risk in AS Not Linked to Family History

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A family history of prostate cancer was not a major determinant of disease progression during active surveillance, according to a systematic review.

Taking Aspirin Regularly May Reduce Death From Cancer

Taking Aspirin Regularly May Reduce Death From Cancer

Regular aspirin use linked to lower risk of cancer mortality, especially colorectal, breast, and prostate cancer.

Earlier vs Later Prostate Cancer Recurrence Characterized

Earlier vs Later Prostate Cancer Recurrence Characterized

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Pathologic Gleason scores, positive surgical margin rates, and PSA doubling times differentiate earlier from later biochemical recurrence after radical surgery.

Lack of Sleep Linked to Prostate Cancer Death in Younger Men

Lack of Sleep Linked to Prostate Cancer Death in Younger Men

Among men under the age of 65, men who got 3 to 5 hours of sleep per night had a 55% greater risk of dying of prostate cancer than men who got 7 hours of sleep per night.

Predictors of Post-RARP Readmission Identified

Predictors of Post-RARP Readmission Identified

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Patients with longer hospital stays and pre-discharge complications were at increased risk of readmission within 30 days of discharge.

Many Men Lack Information on PSA Screening Pros, Cons

Many Men Lack Information on PSA Screening Pros, Cons

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In 2014, 33.9% of men reported that their health care providers failed to communicate the benefits and risks of PSA-based screening, an increase from 2012.

Study Supports PCa Screening With MRI vs TRUS-biopsy

Study Supports PCa Screening With MRI vs TRUS-biopsy

Population-based prostate cancer screening with MRI has a significantly better risk/benefit ratio.

Study Finds Low Rate of AS Failure Regardless of PCa Risk

Study Finds Low Rate of AS Failure Regardless of PCa Risk

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Select intermediate- and high-risk patients had no greater risks of metastases, AS failure, or interventions over a median of 4 years.

Prostate Cancer Active Surveillance Does Not Up Metastasis Risk

Prostate Cancer Active Surveillance Does Not Up Metastasis Risk

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Study finds no difference in metastasis-free survival observed after 15 years compared with radiation therapy or radical prostatectomy.

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