Prostate Cancer

'Jekyll & Hyde' Molecule Could Lead to Aggressive Prostate Cancer (PCa)

'Jekyll & Hyde' Molecule Could Lead to Aggressive Prostate Cancer (PCa)

Prostate cancer (PCa) patients who have the Endo180 protein present in their tumors tend to have a more aggressive form of the disease.

Overweight Men Face Higher Risk of Aggressive Prostate Cancer (PCa)

Overweight Men Face Higher Risk of Aggressive Prostate Cancer (PCa)

Obese men are at a greater risk of developing more advanced forms of prostate cancer (PCa).

Statin Plus Metformin May Reduce Prostate Cancer Relapse Risk

Statin Plus Metformin May Reduce Prostate Cancer Relapse Risk

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Dual use of both drugs significantly reduced the risk of biochemical prostate cancer recurrence after radical surgery.

Walnuts Slow Prostate Cancer Tumor Growth

Walnuts Slow Prostate Cancer Tumor Growth

Diets rich in walnuts or walnut oils slow prostate cancer (PCa) tumor growth in mice.

Optimal PSA Threshold For Targeted Biopsy Identified

Optimal PSA Threshold For Targeted Biopsy Identified

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Diagnostic usefulness of magnetic resonance imaging/ultrasound (MRI/US) fusion targeted prostate biopsy optimized in PSA level of 5.2 ng/mL or higher.

Prostate Cancer Tumor Growth Halted Through Injection

Prostate Cancer Tumor Growth Halted Through Injection

Scientists have discovered a way to "switch off" prostate cancer (PCa) cell production in mice with a thrice-weekly injection.

Prolonged Prostate Cancer Hormone Therapy Raises Fracture Risk

Prolonged Prostate Cancer Hormone Therapy Raises Fracture Risk

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Androgen-deprivation therapy (ADT) for more than 1 year is associated with a 2.5 times higher odds of fracture in prostate cancer patients.

Rising PSA with Testosterone Gel Linked with Specific Factors

Rising PSA with Testosterone Gel Linked with Specific Factors

Greater PSA increases seen in older men and those with lower baseline testosterone.

BRCA Carriers Face Worse Outcomes After Prostate Cancer Treatment

BRCA Carriers Face Worse Outcomes After Prostate Cancer Treatment

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Compared with noncarriers, BRCA carriers experience metastatic prostate cancer sooner and have shorter survival.

New Guideline for Radiation After Prostatectomy Endorsed by ASCO

New Guideline for Radiation After Prostatectomy Endorsed by ASCO

Guideline outlines use of adjuvant and salvage radiotherapy after surgery for prostate cancer.

New Tool Can Test Prostate Cancer Drug Potential

New Tool Can Test Prostate Cancer Drug Potential

AMACR enzyme is being developed to test the potential for prostate cancer drugs.

Early Prostate Cancer Post-Operation PSA Values Useful

Early Prostate Cancer Post-Operation PSA Values Useful

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PSA levels at day 30 found to predict biochemical relapse risk in men with positive surgical margins.

Blacks with Recurrent Prostate Cancer More Likely To Regret Treatment

Blacks with Recurrent Prostate Cancer More Likely To Regret Treatment

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Racial differences in prostate cancer (PCa) treatment regret more pronounced among those without sexual problems.

Androgen Deprivation Therapy (ADT) Raises Heart-Related Death Risk

Androgen Deprivation Therapy (ADT) Raises Heart-Related Death Risk

But overall risk of heart-related death risk from prostate cancer treatment is small, researchers say.

Men with More Female Partners Have Lower Prostate Cancer (PCa) Risk

Men with More Female Partners Have Lower Prostate Cancer (PCa) Risk

Men who have slept with more than 20 female partners are less likely to develop aggressive prostate cancer (PCa).

Prostate Cancer Radiotherapy Outcomes Worse in Smokers

Prostate Cancer Radiotherapy Outcomes Worse in Smokers

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Patients who smoke during external beam radiotherapy (EBRT) are at increased risk of distant metastases and dying from prostate cancer.

Eating More Tomatoes Lowers Prostate Cancer (PCa) Risk

Eating More Tomatoes Lowers Prostate Cancer (PCa) Risk

Consuming ten portions of tomatoes a week can lower the risk of prostate cancer.

Aspirin May Lower Non-Metastatic Prostate Cancer Mortality

Aspirin May Lower Non-Metastatic Prostate Cancer Mortality

Significant association observed for high-risk prostate cancers with no difference according to daily dose.

Vitamin D May Suppress Prostate Tissue Inflammation

Vitamin D May Suppress Prostate Tissue Inflammation

Vitamin D may be able to suppress inflammation in prostate tissue by boosting expression of the GDF-15 gene.

Prostate Cancer Risk Not Linked to Fertility

Prostate Cancer Risk Not Linked to Fertility

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Fathering of dizygotic twins, a marker of high fertility, was not associated with increased risk of prostate cancer.

ConfirmMDx Genetic Test Identifies Prostate Cancer Aggressiveness

ConfirmMDx Genetic Test Identifies Prostate Cancer Aggressiveness

New data confirms that ConfirmMDx, an epigenetic assay, is able to accurately identify prostate cancer aggressiveness

Testosterone Replacement Therapy (TRT) May Promote Prostate Tumor Growth

Testosterone Replacement Therapy (TRT) May Promote Prostate Tumor Growth

Testosterone replacement therapy (TRT) may promote prostate cancer tumor growth.

Prostate Cancer Recurrence After Surgery Linked to High Lipids

Prostate Cancer Recurrence After Surgery Linked to High Lipids

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Abnormal triglyceride levels found to increase the post-radical prostatectomy risk of biochemical relapse by 35%.

High Cholesterol Linked with Prostate Cancer Recurrence

High Cholesterol Linked with Prostate Cancer Recurrence

Findings suggest that normalization of blood fats may reduce risk of prostate cancer.

Prostate Cancer Death Risk Higher After External Beam Radiation Therapy (EBRT) than Surgery

Prostate Cancer Death Risk Higher After External Beam Radiation Therapy (EBRT) than Surgery

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Mortality was greater with external beam radiotherapy across treatment-specific nomograms for predicting biochemical recurrence.

In Black Prostate Cancer Patients, Active Surveillance Safe

In Black Prostate Cancer Patients, Active Surveillance Safe

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Researchers confident in this approach because candidates for active surveillance are a heavily screened population.

Gene Can Predict Aggressive Prostate Cancer at Diagnosis

Gene Can Predict Aggressive Prostate Cancer at Diagnosis

A biomarker present on the KLK3 gene can predict which GS7 prostate cancer patients will be more aggressive.

Robotic Prostate Cancer Surgery Widely Used

Robotic Prostate Cancer Surgery Widely Used

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Growth in robot-assisted radical prostatectomy (RARP) use especially pronounced among surgeons at urban hospitals.

Smoking Raises Prostate Cancer Death Risk

Smoking Raises Prostate Cancer Death Risk

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Meta-analysis shows that the risk is increased 20% with each 20 cigarettes smoked per day.

Prostate Biopsy Complication Rates Increasing

Prostate Biopsy Complication Rates Increasing

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Urologic complications requiring hospital admission grew from 3.6% in 2000 to 3.9% in 2008, largely because of infections.

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