Prostate Cancer

Short-term Arterial Thromboembolism Risk Elevated in Cancer Patients

Short-term Arterial Thromboembolism Risk Elevated in Cancer Patients

The six-month cumulative incidence of myocardial infarction was 2.0% and 0.7% in patients with cancer and controls, respectively.

Cancer Patient Self-Reporting Reliable and Feasible, Studies Show

Cancer Patient Self-Reporting Reliable and Feasible, Studies Show

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Prostate cancer patients accurately report their comorbidities, and participants in cancer clinical trials report more adverse events than trial investigators.

Osteoporosis Drugs Up Bone Mineral Density in Nonmetastatic PCa

Osteoporosis Drugs Up Bone Mineral Density in Nonmetastatic PCa

Improvement in BMD was seen with denosumab, which also reduced the incidence of new radiographic vertebral fractures in one high-quality trial.

Not All High-Risk Prostate Cancers Are the Same

Not All High-Risk Prostate Cancers Are the Same

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Men with 1 high-risk factor experience better outcomes following treatment than those with 2 or 3 high-risk factors, study finds.

Blacks Less Likely to Undergo Definitive Prostate Cancer Therapy

Blacks Less Likely to Undergo Definitive Prostate Cancer Therapy

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Study of men with intermediate- or high-risk prostate cancer finds facility-level racial disparity in use of definitive treatment.

Timing of PSA Nadir Post-RP Predicts Biochemical Recurrence Risk

Timing of PSA Nadir Post-RP Predicts Biochemical Recurrence Risk

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A detectable PSA nadir combined with shorter time to nadir after prostate cancer surgery is associated with a higher risk of biochemical recurrence.

Positive Lymph Node Prostate Cancer Care Patterns Characterized

Positive Lymph Node Prostate Cancer Care Patterns Characterized

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63% of patients were managed initially with observation.

Active Surveillance for Intermediate-Risk PCa May Be Unsafe

Active Surveillance for Intermediate-Risk PCa May Be Unsafe

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Nearly 1 in 3 patients diagnosed with Gleason 3+4 favorable intermediate-risk prostate cancer had their disease upgraded or upstaged at radical prostatectomy.

Top Complaint After Prostate Biopsy Is Infection

Top Complaint After Prostate Biopsy Is Infection

Most common infection in prostate biopsy was E. coli, followed by mild bleeding.

Vascular Targeted Photodynamic Tx Tied to Good Outcomes in Low-Risk PCa

Vascular Targeted Photodynamic Tx Tied to Good Outcomes in Low-Risk PCa

Throughout the study, a total of 115 lobes were treated and 82% achieved absent clinically significant cancer.

Vasectomy Poses Minimal Risk of Prostate Cancer

Vasectomy Poses Minimal Risk of Prostate Cancer

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Researchers calculated that the absolute increase in lifetime risk of prostate cancer associated with vasectomy was just 0.6%.

Active Surveillance for Intermediate-risk Prostate Cancer Challenged

Active Surveillance for Intermediate-risk Prostate Cancer Challenged

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Study reveals that a quarter of men with low-volume intermediate-risk prostate cancer had adverse pathologic features found at radical prostatectomy.

Tall, Obese Men More Likely to Have Aggressive Prostate Cancer

Tall, Obese Men More Likely to Have Aggressive Prostate Cancer

Every additional 4 inches of height was associated with a 21% increase in risk of being diagnosed with high-grade prostate cancer, and a 17% increased risk of dying from prostate cancer.

RP for Prostate Cancer May Not Offer Survival Advantage

RP for Prostate Cancer May Not Offer Survival Advantage

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Randomized trial found no significant difference in all-cause and cancer-specific survival between radical prostatectomy and observation for localized prostate cancer.

Decisional Regret Doesn't Vary by Tx in PCa

Decisional Regret Doesn't Vary by Tx in PCa

Across time, only African-American race correlated with greater regret.

Germline Mutations Up in PCa Patients With Another Primary Cancer

Germline Mutations Up in PCa Patients With Another Primary Cancer

Men with prostate cancer and at least one additional primary cancer are enriched for harboring a germline deleterious mutation in a cancer-predisposing gene.

Radical Prostatectomy Use for High-Risk Prostate Cancer Rises Sharply

Radical Prostatectomy Use for High-Risk Prostate Cancer Rises Sharply

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Over a 10-year period, radical prostatectomy use increased steadily while radiotherapy use declined

Prostate Atrophy, Inflammation Associated With Lower PCa Risk

Prostate Atrophy, Inflammation Associated With Lower PCa Risk

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Both findings on biopsy also predict a lower odds of high-grade cancer.

Negative Confirmatory Biopsy a Good Sign in Prostate Cancer AS

Negative Confirmatory Biopsy a Good Sign in Prostate Cancer AS

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Prostate cancer patients on active surveillance who have no cancer found on confirmatory biopsy have a reduced risk of grade and volume reclassification.

PSA Testing in Controls of Screening Trial May Undermine Results

PSA Testing in Controls of Screening Trial May Undermine Results

Over 15 years of follow-up, considerable proportion of men undergo prostate-specific antigen testing

Novel Markers May Predict Prostate Cancer in Non-Black Men

Novel Markers May Predict Prostate Cancer in Non-Black Men

No added benefit was seen with the addition of biomarkers for African-American men.

Multimodal Therapy Found to Benefit Men With LN-positive PCa

Multimodal Therapy Found to Benefit Men With LN-positive PCa

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New findings suggest that clinicians consider the pathologic characteristics of the primary tumor as well as the burden of LN metastases when deciding on management, investigators say.

Post-RP Radiotherapy Benefits Selected Men With Elevated PSA

Post-RP Radiotherapy Benefits Selected Men With Elevated PSA

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Radiotherapy for prostate cancer patients with persistently elevated PSA after radical surgery improved survival only among those with worse pathologic characteristics.

Prostate Cancer Tests Are Fine With Patients Permission

Prostate Cancer Tests Are Fine With Patients Permission

Routine prostate cancer screenings can be done as long as the patient makes the decision after a physician consultation.

High-income US Counties Have Higher Diagnoses of PCa

High-income US Counties Have Higher Diagnoses of PCa

High-income counties had far higher diagnosis rates for the four cancers than low-income counties, but the combined mortality rate was similar for both.

Survival Up With Patient-Reported Symptom Monitoring During Chemo

Survival Up With Patient-Reported Symptom Monitoring During Chemo

The researchers found that the median overall survival was 31.2 and 26.0 months in the PRO and usual care groups, respectively.

Men Need Better Understanding of PCa Genetic Test Results

Men Need Better Understanding of PCa Genetic Test Results

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Some men who undergo multigene testing for inherited prostate cancer misinterpret findings of variants of uncertain significance.

Surgery May Offer Better Survival for Younger Men With High-risk PCa

Surgery May Offer Better Survival for Younger Men With High-risk PCa

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Younger patients who chose surgery vs radiation for initial treatment had a 48% survival advantage.

Extended PLND Not Associated With Short-Term Oncologic Benefits

Extended PLND Not Associated With Short-Term Oncologic Benefits

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Extended pelvic lymph node dissection versus limited dissection during radical prostatectomy does not improve biochemical recurrence rates.

Chronic Prostatitis Has Adverse Effects on Sperm

Chronic Prostatitis Has Adverse Effects on Sperm

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CBP was associated with a reduction in sperm concentration, sperm vitality, sperm total and progressive motility.

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