Over 15 years of follow-up, considerable proportion of men undergo prostate-specific antigen testing
No added benefit was seen with the addition of biomarkers for African-American men.
New findings suggest that clinicians consider the pathologic characteristics of the primary tumor as well as the burden of LN metastases when deciding on management, investigators say.
Radiotherapy for prostate cancer patients with persistently elevated PSA after radical surgery improved survival only among those with worse pathologic characteristics.
Routine prostate cancer screenings can be done as long as the patient makes the decision after a physician consultation.
High-income counties had far higher diagnosis rates for the four cancers than low-income counties, but the combined mortality rate was similar for both.
The researchers found that the median overall survival was 31.2 and 26.0 months in the PRO and usual care groups, respectively.
Renal & Urology News spoke with two researchers who have been involved in studies of these agents: E. David Crawford, MD, and Tomasz M. Beer, MD.
Some men who undergo multigene testing for inherited prostate cancer misinterpret findings of variants of uncertain significance.
Younger patients who chose surgery vs radiation for initial treatment had a 48% survival advantage.
Extended pelvic lymph node dissection versus limited dissection during radical prostatectomy does not improve biochemical recurrence rates.
CBP was associated with a reduction in sperm concentration, sperm vitality, sperm total and progressive motility.
New findings establish single-dose radiotherapy as the standard of care for metastatic spinal canal compression, at least for patients with a short life expectancy, researcher says.
ECOG status and baseline PSA and PSADT are significantly associated with overall survival.
Men with PSA values of 2.5 ng/mL or less and Gleason 8 to 10 prostate tumors are at higher risk of death than other high-risk PCa patients.
The researchers found that predicted monthly costs remained relatively stable throughout the observation period among the controls.
Addition of abiraterone to androgen deprivation therapy for patients with hormone-naïve advanced prostate cancer may be a new standard of care.
The 3-year overall survival rate among prostate cancer patients starting long-term hormone therapy was 83% vs 76% for men receiving abiraterone plus ADT vs ADT alone.
Urinary incontinence and diminished sexual function were common after a median follow-up of nearly 15 years, study finds.
Overall complication rates were similar between primary and salvage RARP groups, but there were some notable differences in prognosis.
Systematic biopsies always should be performed in conjunction with targeted biopsy in men with suspected clinically significant PCa at mpMRI.
The new test, IsoPSA, measures all PSA isoforms in serum and more accurately discriminates high-grade cancer from benign disease.
Combining testing of urinary T2:ERG, PCA3 at thresholds that detected aggressive prostate cancer improved specificity from 18% to 39%.
The investigators found that the percentage of patients diagnosed with stage I cancer increased significantly from 2013 to 2014 after the ACA was implemented.
Only luminal B prostate cancers were significantly associated with postoperative response to ADT in a subset analysis in retrospective cohorts.
A majority of active surveillance patients under age 60 did not progress to definitive prostate cancer treatment.
Targeting PI-RADS 4 and 5 lesions for confirmatory biopsy improves detection of clinically significant cancer.
Median overall survival was 9.3 months longer for black versus white patients with metastatic castration-resistant prostate cancer.
Fusion biopsy has improved over the last decade and increasingly detects clinically significant prostate cancer, according to data trends from one institution.
Highest quartile of alkaline phosphatase velocity in men who experience biochemical recurrence after radical prostatectomy is associated with 2-fold higher risk.
Renal and Urology News Articles
- Study: Ureterolithotripsy Best for Large Proximal Ureteral Stones
- Post-RP Radiotherapy Benefits Selected Men With Elevated PSA
- Erectile Dysfunction Risk Higher in Gout Patients
- Switch to an Iron-Based Binder Found to Improve Phosphorus Lowering
- Multimodal Therapy Found to Benefit Men With LN-positive PCa
Sign Up for Free e-newsletters
NEPHROLOGY & UROLOGY NEWS
- Acute Kidney Injury (AKI)
- Chronic Kidney Disease (CKD)
- Contrast Nephropathy
- Cardiovascular Disease (CVD)
- Diabetic Nephropathy
- End-stage Renal Disease (ESRD)
- Lupus Nephritis
- Peritoneal Dialysis
- Secondary Hyperparathyroidism (SHPT)