Video Series: Current Topics in the Treatment of Advanced PCa
Philip Kantoff, MD, Andrew Armstrong, MD, William Oh, MD, and A. Oliver Sartor, MD, discuss advances in treatment of castration-resistant prostate cancer and metastatic castration-resistant prostate cancer, specifically newer hormonal therapies.
Latest Prostate Cancer News
Early prostate cancer diagnosis rates fell, while cases of advanced prostate cancer remained stable.
Overall decision regret for 16.9% of patients; more regret for RP than radiotherapy component.
Survival was longer in patients who received radium-223 plus abiraterone, enzalutamide, or both.
Men who used the medications prior to radical prostatectomy had 83% greater odds of Gleason 7-10 tumors compared with non-users.
Prostatectomy and radiotherapy with or without ADT reduced prostate cancer-specific and all-cause mortality rates.
Androgen deprivation increased all-cause mortality risk by 77% among black men who underwent brachytherapy for favorable-risk prostate cancer.
An analysis of individual participant data from 15 prospective studies suggests a protective effect.
Prostate cancer was diagnosed in 19.5% of PDE5i users vs 22.7% of nonusers, a statistically insignificant difference.
Skeletal-related events occurred in 38% of patients with metastatic castration-resistant prostate cancer.
ADT for prostate cancer may be associated with a reduced risk of inflammatory bowel disease.
Ethnicity, education identified as factors that influence patients treatment decisions.
Prevalence of obesity is high in adults with a history of breast, prostate, or colorectal cancer.
External beam radiation therapy (EBRT) plus brachytherapy found to offer improved systemic control versus EBRT alone and radical prostatectomy.
No significant differences observed in standard oncologic outcomes and quality of life at 12 weeks.
Blacks found to be slightly more likely than whites to leave observational management to undergo radiotherapy or surgery.
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