Features

PIVOT Study Results Challenged

Researchers question the generalizability of a major study showing no significant difference in cancer-specific and overall survival between surgery and observation for localized prostate cancer.

Managing Lymph Node-Positive PCa

In patients with suspicious lymph node involvement at preoperative imaging, radiation therapy or radical prostatectomy with or without systemic therapies should be recommended as part ...

New Ways to Cut Prostate Biopsy Infection Risk

Alcohol needle washing and pre-biopsy rectal cultures for targeted prophylaxis are among the potentially beneficial strategies.

Extended Lymph Node Dissection for PCa

Study shows that the risk of recurrence after salvage radiotherapy is inversely related to the number of nodes resected at radical prostatectomy.

Management of Oligometastatic PCa

More and more cases of oligometastatic PCa are being diagnosed as a result of advances in molecular imaging, but clinical trial data about the best ...

Latest Prostate Cancer News

Prostate Cancer ADT Ups Thromboembolic Event Risk

Prostate Cancer ADT Ups Thromboembolic Event Risk

Pulmonary embolism is associated with GnRH agonist use and orchiectomy.

Partial Brachytherapy May Lead to Poor Outcomes in Intermediate-Risk PCa

Partial Brachytherapy May Lead to Poor Outcomes in Intermediate-Risk PCa

The impact of partial brachytherapy on metastasis and disease-specific mortality is unclear.

Advanced Prostate Cancer Variant More Common Than Thought

Advanced Prostate Cancer Variant More Common Than Thought

Incidence of tx-emergent small-cell neuroendocrine prostate cancer 17% among those with mCRPC.

Focal HIFU Effective Over 5 Years for PCa

Focal HIFU Effective Over 5 Years for PCa

Failure-free survival was 88% at 5 years among patients with nonmetastatic prostate cancer who underwent focal therapy with high-intensity focused ultrasound.

Automated Bone Scan Index Prognostic for Prostate Cancer

Automated Bone Scan Index Prognostic for Prostate Cancer

aBSI validated as prognostic biomarker of survival in metastatic castration-resistant prostate cancer

Conservative Management Up for Low-Risk Prostate Cancer in Veterans

Conservative Management Up for Low-Risk Prostate Cancer in Veterans

More conservative management and active surveillance utilized at VA hospitals from 2005 to 2015.

Metformin Added to Prostate Cancer ADT Ups Survival

Metformin Added to Prostate Cancer ADT Ups Survival

Metformin plus androgen deprivation therapy is associated with a lower death risk vs ADT alone in men without diabetes, study of US veterans shows.

Enzalutamide Delays Metastasis in CRPC

Enzalutamide Delays Metastasis in CRPC

Men receiving enzalutamide plus ADT had a significant 71% lower risk for metastasis or death compared with men receiving placebo plus ADT.

Testosterone Levels May Be Determined in Childhood

Testosterone Levels May Be Determined in Childhood

Children who migrated to the UK from Bangladesh before puberty and Bangladeshis born in the UK had significantly higher levels of testosterone compared with life-long residents of Bangladesh.

Prostate Cancer Vaccine Found Not to Improve Survival

Prostate Cancer Vaccine Found Not to Improve Survival

In a phase 3 trial, Prostvac-V/F did not significantly prolong overall survival among men with asymptomatic or minimally symptomatic mCRPC.

End-of-Life Prostate Cancer-Related Complications Characterized

End-of-Life Prostate Cancer-Related Complications Characterized

Men with advanced prostate cancer at diagnosis have an elevated risk of spinal cord compression, renal failure, and other cancer-related morbidities.

Prostate Biopsy Complications Deter Patients From Re-Biopsy

Prostate Biopsy Complications Deter Patients From Re-Biopsy

Study participants with acute urinary retention after TRUS-guided prostate biopsy were 4.5 times more likely to skip a recommended re-biopsy than men who had no initial biopsy-related complications.

Long-Term Data Support Finasteride for PCa Prevention

Long-Term Data Support Finasteride for PCa Prevention

Clinicians can rest easier about recommending finasteride to more men, according to experts.

Prostate Cancer Treatment Side Effects Linked to Distress

Prostate Cancer Treatment Side Effects Linked to Distress

Those with worse emotional distress also report worse urinary, sexual, bowel functions.

Biparametric MRI Improves Detection of Significant PCa

Biparametric MRI Improves Detection of Significant PCa

If externally validated, bpMRI could be used to triage men for prostate biopsy.

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