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Commentary Prostate Cancer Genetics: Ready for Clinical Use?

Prostate Cancer Genetics: Ready for Clinical Use?

For decades, prostate cancer risk (PCa) stratification was based primarily on the architectural pattern of the tumor.

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Preoperative MRI May Benefit Some Prostate Surgery Patients

Preoperative MRI May Benefit Some Prostate Surgery Patients

Imaging was associated with a lower risk of positive surgical margins in men with cT1 prostate tumors, but not in other subgroups.

Cause of Post-RP Death in High-Risk PCa Patients Linked to Age

Cause of Post-RP Death in High-Risk PCa Patients Linked to Age

Within 10 years of surgery, men younger than 60 years are more likely to die from prostate cancer than from other causes.

Return to Full Potency Rare After Prostate Surgery

Return to Full Potency Rare After Prostate Surgery

Only 6.7% of men reported erections that were as good after radical prostatectomy, as before—much lower than would be expected by IIEF-5 scores.

Prostate Cancer Recurrence Risk After Surgery Higher in Smokers

Prostate Cancer Recurrence Risk After Surgery Higher in Smokers

Even patients who quit smoking less than 10 years after radical prostatectomy are at increased risk.

Low Testosterone After ADT Linked with Improved Survival

Low Testosterone After ADT Linked with Improved Survival

Low serum testosterone levels within the first year of androgen-deprivation therapy (ADT) is associated with improved cause-specific survival.

Factors Affecting Treatment Regret in Prostate Cancer

Factors Affecting Treatment Regret in Prostate Cancer

The researchers found that 12% of the participants experienced treatment decisional regret.

CVD Risk Increased in Patients on Androgen Deprivation Therapy for Prostate Cancer

CVD Risk Increased in Patients on Androgen Deprivation Therapy for Prostate Cancer

Highest risk during first 6 months of ADT among men who had cardiovascular events before treatment.

Fatal Prostate Cancer Not Associated with Vitamin D

Fatal Prostate Cancer Not Associated with Vitamin D

Also, no significant associations found between vitamin D-related SNPs and fatal prostate cancer

Low-Grade Prostate Cancers Rarely Metastasize

Low-Grade Prostate Cancers Rarely Metastasize

In a study, not a single case of metastatic disease developed among 449 men who had a tumor grade of Gleason 6 or less at radical prostatectomy.

PCa Family History May Raise Breast Cancer Risks

PCa Family History May Raise Breast Cancer Risks

Doctors should ask women about the medical history of their first-degree male relatives, researchers say

IMRT Used Less in Black Prostate Cancer Patients

IMRT Used Less in Black Prostate Cancer Patients

African American patients are less likely than Caucasians to receive intensity-modulated radiation therapy for localized prostate cancer.

Metformin May Reduce Prostate Cancer Recurrence Risk

Metformin May Reduce Prostate Cancer Recurrence Risk

Meta-analysis shows that use of medication is associated with an 18% lower risk.

Low-dose Brachytherapy Provides Better Outcomes in Intermediate PCa

Low-dose Brachytherapy Provides Better Outcomes in Intermediate PCa

Low-dose-rate brachytherapy boost (LDR-PB) achieves better rates of biochemically disease-free outcomes in prostate cancer.

Nerve Wrap May Hasten Potency Return

Nerve Wrap May Hasten Potency Return

The average time to return of continence and potency following prostatectomy was significantly shorter in the allograft than no-allograft group.