Prostate Cancer News Archive

Smoking Ups Bladder Cancer Risk, Lowers Prostate Cancer Risk

Smoking Ups Bladder Cancer Risk, Lowers Prostate Cancer Risk

Men and women who smoke are at 2.3-fold and 2.7-fold increased risk of bladder cancer compared with non-smokers.

Cancer Incidences and Burden Expected to Shift in HIV-Positive

Cancer Incidences and Burden Expected to Shift in HIV-Positive

Prostate and lung cancer expected to emerge as the most common types by 2030.

USPSTF Updates Prostate Cancer Screening Recommendations

USPSTF Updates Prostate Cancer Screening Recommendations

The new statement emphasizes shared decision-making on screening for men aged 55 to 69 years who are at average risk for prostate cancer.

Surgical Overtreatment of Prostate Cancer May Be Decreasing

Surgical Overtreatment of Prostate Cancer May Be Decreasing

Canadian study shows that nearly all men undergoing radical prostatectomy in Eastern Ontario in recent years have clinically significant prostate cancer.

Gleason 4+3 vs 3+4 PCa Tied To Higher Risk of Metastasis at Diagnosis

Gleason 4+3 vs 3+4 PCa Tied To Higher Risk of Metastasis at Diagnosis

Men with Gleason score (GS) 4+3 prostate cancer have a 3-fold higher risk of distant metastasis at diagnosis than those with GS 3+4 PCa.

Obesity Linked to Lower Death Risk in Non-metastatic CRPC

Obesity Linked to Lower Death Risk in Non-metastatic CRPC

Obese men with non-metastatic castration-resistant prostate cancer have a 21% decreased risk of death compared with normal weight men, according to a study.

Cancer Screening More Likely After a Previous False Positive

Cancer Screening More Likely After a Previous False Positive

Findings for both men and women with a false-positive prostate or breast cancer test result.

BRCA Mutations Up Risk for PCa, Other Cancers

BRCA Mutations Up Risk for PCa, Other Cancers

Increased incidence of malignant disease, specifically prostate, melanoma, pancreas, breast cancers

Survey Highlights Emotional Responses to Prostate Cancer

Survey Highlights Emotional Responses to Prostate Cancer

Sexual dysfunction was a chief complaint among survey respondents with prostate cancer.

Myocarditis Rare Side Effect of Immune Checkpoint Inhibitors

Myocarditis Rare Side Effect of Immune Checkpoint Inhibitors

Myocarditis with ICIs may be more common than initially thought; responds to higher steroid dosages

Diet, Exercise With Behavioral Counseling Can Reduce ADT Side Effects

Diet, Exercise With Behavioral Counseling Can Reduce ADT Side Effects

A novel component of an interventional program was cognitive-behavioral counseling administered in a group setting to promote behavioral change.

Socioeconomics May Not Explain Racial Gap in Prostate Cancer Mortality

Socioeconomics May Not Explain Racial Gap in Prostate Cancer Mortality

In a study, race independently predicted prostate cancer-specific mortality beyond a number of risk factors, including health insurance status.

Low-Dose Abiraterone Noninferior for Castration-Resistant PCa

Low-Dose Abiraterone Noninferior for Castration-Resistant PCa

Low-dose AA with low-fat breakfast had greater effect on PSA; similar effect to standard dose

Adjuvant RT Plus ADT Beneficial in Selected Prostate Cancer Cases

Adjuvant RT Plus ADT Beneficial in Selected Prostate Cancer Cases

Study identifies which PCa patients with positive lymph nodes may have improved survival with the addition of adjuvant radiotherapy to androgen-deprivation therapy.

Biopsy-to-RP Delay May Up Prostate Cancer Recurrence Risk

Biopsy-to-RP Delay May Up Prostate Cancer Recurrence Risk

Researchers concluded that a greater than 90-day interval from prostate biopsy to radical prostatectomy increases the risk of biochemical recurrence among men with Gleason 3+4 disease.

Metastatic Prostate Cancer at Diagnosis in Decline

Metastatic Prostate Cancer at Diagnosis in Decline

Study documents a drop in the incidence of de novo metastatic PCa from 1980 to 2011 in the United States.

Finasteride Cuts Prostate Cancer Risk Long Term

Finasteride Cuts Prostate Cancer Risk Long Term

New study shows that men are at lower risk of prostate cancer for years after they stop taking the medication.

MRI Scans Can Avert Many Prostate Biopsies

MRI Scans Can Avert Many Prostate Biopsies

In a large international trial, pre-biopsy MRI scans spared 28% of men from having to undergo a biopsy and resulted in a lower detection of clinically insignificant cancers vs standard biopsy.

Dose-Escalated RT Does Not Improve Survival in Intermediate-Risk PCa

Dose-Escalated RT Does Not Improve Survival in Intermediate-Risk PCa

Researchers observed reductions in biochemical failure and distant metastasis rates in patients who had dose-escalated radiation therapy.

No Advantages With Aggressive Treatment in Metastatic Prostate Cancer

No Advantages With Aggressive Treatment in Metastatic Prostate Cancer

However, mortality higher with conservative therapy in locally advanced, non-metastatic prostate cancer.

Single PSA Screening Has No Effect on Prostate Cancer Mortality

Single PSA Screening Has No Effect on Prostate Cancer Mortality

Findings from a large study of men in the United Kingdom do not support single PSA testing for population-based screening.

EBRT+BT+ADT May Be Optimal for High-Grade PCa

EBRT+BT+ADT May Be Optimal for High-Grade PCa

In a study, extremely dose-escalated radiotherapy combined with androgen deprivation therapy offered the best cancer-specific survival among men with Gleason 9-10 prostate cancer.

Nocturia May Contribute to Sleep Problems in ADT Recipients

Nocturia May Contribute to Sleep Problems in ADT Recipients

In a 12-month study, men with prostate cancer treated with ADT reported more nocturia episodes than men with prostate cancer treated with prostatectomy alone and men with no history of cancer.

MRI May Help Cut Down on Unnecessary Prostate Biopsies

MRI May Help Cut Down on Unnecessary Prostate Biopsies

Multiparametic MRI findings added to conventional clinical predictors decreases the number of false-positive biopsy results without increasing the number of clinically significant tumors left undiagnosed, study finds.

FDA Oks Drug for Non-metastatic Castration-Resistant Prostate Cancer

FDA Oks Drug for Non-metastatic Castration-Resistant Prostate Cancer

Apalutamide prolonged metastasis-free survival by 2 years compared with placebo.

Upfront Docetaxel May Have Role in Advanced Prostate Cancer

Upfront Docetaxel May Have Role in Advanced Prostate Cancer

Added to hormone therapy, docetaxel offers a cost effective way to prolong hormone-sensitive disease and improve quality of life years, especially among men with non-metastatic disease, study finds.

Inclusion Criteria for PCa Trials Inadvertently Exclude Blacks

Inclusion Criteria for PCa Trials Inadvertently Exclude Blacks

Trials sponsored by academic investigators, cooperative groups more likely to use these criteria

Low-Carb Diet Tested as Way to Slow Recurrent Prostate Cancer

Low-Carb Diet Tested as Way to Slow Recurrent Prostate Cancer

In a small phase 2 study of overweight men with recurrent prostate cancer, consuming less than 20 grams of carbohydrates a day resulted in profound weight loss.

PSA Trajectory in nmCRPC Predicts Metastasis, Mortality Risk

PSA Trajectory in nmCRPC Predicts Metastasis, Mortality Risk

Metastasis and death are more likely to occur among patients with relatively high PSA levels at diagnosis of nmCRPC and rising PSA levels during follow-up.

Adverse Prostate Cancer Pathology Accurately Predicted With MRI

Adverse Prostate Cancer Pathology Accurately Predicted With MRI

Multiparametric MRI has high positive and negative predictive values for extracapsular extension, seminal vesicle invasion, lymph node involvement, and high-risk Gleason score.

Urologic Cancer Surgery Readmission Rate Highest for RC

Urologic Cancer Surgery Readmission Rate Highest for RC

In a study, nearly 20% of radical cystectomy patients were readmitted for complications within 90 days compared with 1.9% and 5.9% for radical prostatectomy and radical nephrectomy, respectively.

Early Prostate Cancer Salvage ADT Therapy Better

Early Prostate Cancer Salvage ADT Therapy Better

Among men who had PSA failure following radiation therapy for localized PCa, those with a long PSA doubling time had an increased risk of PCa mortality if they started androgen-deprivation therapy later.

Prostate Cancer Pathologic Features Worse in Blacks

Prostate Cancer Pathologic Features Worse in Blacks

Black men undergoing radical prostatectomy for prostate cancer are more likely to have indications for adjuvant radiotherapy compared with white men.

Statin Use May Improve Survival in Advanced Prostate Cancer

Statin Use May Improve Survival in Advanced Prostate Cancer

Statin use is associated with greater overall survival among men with metastatic castration-resistant prostate cancer and improved survival among patients with high-risk prostate cancer.

Negative Repeat Biopsy in PCa Active Surveillance a Positive Sign

Negative Repeat Biopsy in PCa Active Surveillance a Positive Sign

In a study, a negative confirmatory prostate biopsy in prostate cancer patients on active surveillance predicts a lower risk of progressing to treatment.

Earlier Prostate Cancer Drug Use in CRPC Cuts Metastasis Risk

Earlier Prostate Cancer Drug Use in CRPC Cuts Metastasis Risk

In separate studies, apalutamide and enzalutamide prolonged metastasis-free survival in men with non-metastatic castration-resistant prostate cancer.

Testosterone Therapy May Reduce PCa Risk in Hypogonadal Men

Testosterone Therapy May Reduce PCa Risk in Hypogonadal Men

In a study of hypogonadal men, those who received testosterone therapy had a lower incidence of prostate cancer than those who did not.

Telementoring Useful for Teaching Robotic Surgery

Telementoring Useful for Teaching Robotic Surgery

The technology facilitates teaching of advanced surgical skills, delivery of care to underserved

Brachytherapy Alone May Be Sufficient for More Risky PCa Cases

Brachytherapy Alone May Be Sufficient for More Risky PCa Cases

The investigators observed no difference in mortality between BT alone and BT plus ADT and/or EBRT supplemental therapy.

LDR Brachytherapy for Prostate Cancer Offers Excellent Survival

LDR Brachytherapy for Prostate Cancer Offers Excellent Survival

In a study, the 17-year prostate cancer-specific and biochemical failure-free survival rates were 97% and 79%, respectively.

Adjuvant Better Than Early Salvage RT for Some High-risk PCa Patients

Adjuvant Better Than Early Salvage RT for Some High-risk PCa Patients

Adjuvant radiotherapy was associated with lower risks for biochemical failure and distant metastases and increased overall survival in patients with adverse pathologic features found after radical prostatectomy.

Obesity, Metabolic Syndrome Increases Risk for PCa Recurrence

Obesity, Metabolic Syndrome Increases Risk for PCa Recurrence

Following radical prostatectomy, higher BMI increases risk of recurrence for prostate cancer.

Prostate Cancer ADT May Up Risk for Thromboembolism

Prostate Cancer ADT May Up Risk for Thromboembolism

Androgen-deprivation therapy without estrogen is associated with a significant 43% increased risk of thromboembolic events, meta-analysis shows.

Fosfomycin Tops Fluoroquinolones for Prostate Biopsy Prophylaxis

Fosfomycin Tops Fluoroquinolones for Prostate Biopsy Prophylaxis

In a meta-analysis, the risk of infectious complications was 78% lower with fosfomycin trometamol versus fluoroquinolones in men undergoing TRUS-guided prostate biopsy.

Routine Office Urine Culture Before Prostate Biopsy Is Unnecessary

Routine Office Urine Culture Before Prostate Biopsy Is Unnecessary

In a single center study, asymptomatic bacteriuria resolved before prostate biopsy, without additional treatment.

Polygenic Hazard Score Predicts Age of Prostate Cancer Diagnosis

Polygenic Hazard Score Predicts Age of Prostate Cancer Diagnosis

Polygenic hazard score can guide screening based off predicted prostate cancer diagnosis age.

PSA at 7 Months Prognostic in Treated mHSPC

PSA at 7 Months Prognostic in Treated mHSPC

A study showed longer survival among patients with metastatic hormone-sensitive prostate cancer who achieved a PSA level of 0.2 ng/mL or less 7 months after initiating ADT.

Mediterranean Diet Best for Lowering Aggressive Prostate Cancer Risk

Mediterranean Diet Best for Lowering Aggressive Prostate Cancer Risk

Study finds that closely adhering to a Mediterranean-style diet possibly protects men from aggressive and advanced prostate cancer.

High-grade Prostate Cancer Risk Again Linked to Cholesterol

High-grade Prostate Cancer Risk Again Linked to Cholesterol

Each 10 mg/dL increase in serum levels of total and HDL cholesterol are associated with a significant 5% and 14% increased risk of high-grade PCa, respectively.

Prostate Cancer Surgery Complications More Likely Among Older Men

Prostate Cancer Surgery Complications More Likely Among Older Men

Patient age 70 years and above is an independent risk factor for perioperative morbidity, according to data from a national cohort.

Odds of Prostate Cancer Treatment With SBRT Linked to Travel Distance

Odds of Prostate Cancer Treatment With SBRT Linked to Travel Distance

Patients who have to travel longer distances for prostate cancer treatment are more likely to receive stereotactic body radiotherapy.

Repeat Prostate Biopsies Do Not Raise Risk of Post-RP Complications

Repeat Prostate Biopsies Do Not Raise Risk of Post-RP Complications

Rates of erectile dysfunction and urinary incontinence at 1, 2, and 3 years after radical surgery are not higher among men who have multiple prostate biopsies while on active surveillance for prostate cancer.

Shift Workers at Higher Risk for Prostate Cancer

Shift Workers at Higher Risk for Prostate Cancer

A rotating shift schedule appeared the most risky.

Smaller Difference in Prostate Cancer Death Risk Found Between RT, RP

Smaller Difference in Prostate Cancer Death Risk Found Between RT, RP

Among patients with high-risk prostate cancer, investigators observe no significant difference in cancer-related death risk between radiotherapy and radical prostatectomy.

High Intakes of Teas, Peas, Soybeans May Increase Prostate Cancer Risk

High Intakes of Teas, Peas, Soybeans May Increase Prostate Cancer Risk

An analysis of an intervention arm of the PLCO Cancer Screening Trial evaluated the risk of prostate cancer relative to dietary consumption of isoflavones, a dietary compound found in some plant foods.

Enzalutamide Does Not Appear to Up Seizures in mCRPC

Enzalutamide Does Not Appear to Up Seizures in mCRPC

Male patients with mCRPC and seizure risk factors did not have increased seizure incidents when taking Enzalutamide.

Severe Acne May Boost Prostate Cancer Risk

Severe Acne May Boost Prostate Cancer Risk

Recent research suggests that P. acnes, which is associated with acne vulgaris, is more likely to be present in the prostatic tissue of patients with the disease than in healthy individuals.

MRI Predicts Outcomes of Prostate Cancer Salvage Radiotherapy

MRI Predicts Outcomes of Prostate Cancer Salvage Radiotherapy

A negative mpMRI is associated with a higher risk for PSA recurrence and metastasis following salvage radiotherapy for recurrent prostate cancer after radical prostatectomy.

Cancer Pts With Private Insurance, Medicare May Have Survival Advantage

Cancer Pts With Private Insurance, Medicare May Have Survival Advantage

Cancer survival was greatly skewed toward patients with Medicare or private insurance.

Less Frequent Biopsies May Be Appropriate for PCa Active Surveillance

Less Frequent Biopsies May Be Appropriate for PCa Active Surveillance

Investigators who compared 4 active surveillance cohorts found that biennial prostate biopsies appear to be an acceptable alternative to annual biopsies.

Prostate Health Index Shown to Decrease Number of Prostate Biopsies

Prostate Health Index Shown to Decrease Number of Prostate Biopsies

Results of a large prospective study show that appropriate use of the phi test can improve physicians' ability to diagnose and manage patients.

PET/CT Imaging Phenotype Tied With Survival in mCRPC

PET/CT Imaging Phenotype Tied With Survival in mCRPC

Assessments of androgen receptor, glycolysis prognostic in castration-resistant prostate cancer.

Testosterone Therapy May Lower Prostate Cancer Incidence

Testosterone Therapy May Lower Prostate Cancer Incidence

Hypogonadal men who received testosterone replacement therapy had a lower incidence of prostate cancer than those who did not, and their cancers were less severe.

Second-Line Enzalutamide May Benefit Some mCRPC Patients

Second-Line Enzalutamide May Benefit Some mCRPC Patients

In a prospective study, mCRPC patients placed on enzalutamide after their disease progressed while on abiraterone therapy had a median radiographic progression-free survival of 8.1 months.

Active Surveillance Required After Prostate Cancer Focal Ablation

Active Surveillance Required After Prostate Cancer Focal Ablation

In a small but meaningful number of patients, Gleason pattern 4 disease missed by MRI and systematic biopsy is present outside the focal ablation zone.

Genetic Variant Predicts Faster Time to Prostate Cancer Metastasis

Genetic Variant Predicts Faster Time to Prostate Cancer Metastasis

The variant HSD3B1 allele increases the likelihood of metastasis in men receiving androgen-deprivation therapy for biochemically recurrent disease after radiotherapy for localized PCa.

Men With PCa Most Likely to Die From Other Causes

Men With PCa Most Likely to Die From Other Causes

Non-metastatic prostate cancer patients are more likely to die from causes other than the disease.

Prostate Cancer Hormone Therapy Ups Cardiac Risks

Prostate Cancer Hormone Therapy Ups Cardiac Risks

Exposure to androgen-deprivation therapy was associated with a nearly 2-fold increased risk of heart failure among men without pre-existing cardiovascular disease.

Brachytherapy + EBRT for High-Risk PCa Offers 'Excellent' Outcomes

Brachytherapy + EBRT for High-Risk PCa Offers 'Excellent' Outcomes

Biochemical failure and prostate cancer-specific mortality rates were 13.3% and 4.9% at 10 years, respectively.

Prostate Cancer Pathologic Stage Alone Independently Predicts BCRFS

Prostate Cancer Pathologic Stage Alone Independently Predicts BCRFS

Pathologic stages T3a and T3b versus T2a were associated with 8.45 and 7.1 times increased risk of biochemical recurrence on multivariable analysis.

Testosterone Patterns Predict Prostate Cancer Risk

Testosterone Patterns Predict Prostate Cancer Risk

The later a man's testosterone level dropped below 12.1 nmol/L, the lower his lifetime risk for prostate cancer.

BRCA2 Mutations Tied With Poor Survival, Progression in mCRPC

BRCA2 Mutations Tied With Poor Survival, Progression in mCRPC

Researchers find BRCA2 mutations are associated with worse outcomes among men with mCRPC.

IMRT for Prostate Cancer Radiation Therapy Soars

IMRT for Prostate Cancer Radiation Therapy Soars

Use of intensity-modulated radiation therapy for prostate cancer increased from 3.5% to 64% from 2002 to 2012.

Prostate Cancer Risk Lower in NSAID Users

Prostate Cancer Risk Lower in NSAID Users

In a case-control study, men who had ever used non-steroid anti-inflammatory drugs had a 23% decreased risk of prostate cancer.

Prostate Cancer Active Surveillance Use Low, But Increasing

Prostate Cancer Active Surveillance Use Low, But Increasing

Use of active surveillance for very low-risk prostate cancer rose from 11.6% of patients in 2010 to 27.3% in 2013, study finds.

First Metastasis Site Predicts Prostate Cancer-Specific Survival

First Metastasis Site Predicts Prostate Cancer-Specific Survival

Following curative treatment for localized PCa, 5-year PCa-specific survival rates are higher for patients with initial lymph node or locoregional metastases versus initial metastases in bone only or in multiple sites.

Additions to Standard Care in High-Risk PCa May Up Survival

Additions to Standard Care in High-Risk PCa May Up Survival

Findings from this comparative study indicate a favorable failure-free survival and progression-free survival with Standard of Care plus abiraterone acetate and prednisone.

Proximal PSA Predicts Prostate Cancer Metastasis Risk

Proximal PSA Predicts Prostate Cancer Metastasis Risk

PSA levels of 10 ng/mL or higher in men who have biochemically recurrent PCa after radical prostatectomy and a PSADT less than 12 months are at imminent risk for metastatic disease.

Toxicity Similar for 6- and 2- Fraction HDR Brachytherapy in PCa

Toxicity Similar for 6- and 2- Fraction HDR Brachytherapy in PCa

The researchers found that there was no difference between the 6- and 2-fraction groups in baseline and post-implantation IPSS scores.

Prostate Cancer Screening Saves Lives, New Analysis Shows

Prostate Cancer Screening Saves Lives, New Analysis Shows

A European trial found a survival benefit from PCa screening and a US trial did not, but a new analysis finds that both trials provide compatible evidence that screening decreases PCa mortality.

Prostate Cancer ADT Linked With Cardiovascular Risks, Depression

Prostate Cancer ADT Linked With Cardiovascular Risks, Depression

In a study, the risk for heart failure was 81% higher among patients who received androgen deprivation therapy.

Urologist Ownership of IMRT Linked to Its Greater Use for PCa

Urologist Ownership of IMRT Linked to Its Greater Use for PCa

Patients are more likely to receive intensity-modulated radiation therapy if they are managed by urology practices with an ownership interest in the modality, study finds.

Short-term Arterial Thromboembolism Risk Elevated in Cancer Patients

Short-term Arterial Thromboembolism Risk Elevated in Cancer Patients

The six-month cumulative incidence of myocardial infarction was 2.0% and 0.7% in patients with cancer and controls, respectively.

Cancer Patient Self-Reporting Reliable and Feasible, Studies Show

Cancer Patient Self-Reporting Reliable and Feasible, Studies Show

Prostate cancer patients accurately report their comorbidities, and participants in cancer clinical trials report more adverse events than trial investigators.

Osteoporosis Drugs Up Bone Mineral Density in Nonmetastatic PCa

Osteoporosis Drugs Up Bone Mineral Density in Nonmetastatic PCa

Improvement in BMD was seen with denosumab, which also reduced the incidence of new radiographic vertebral fractures in one high-quality trial.

Not All High-Risk Prostate Cancers Are the Same

Not All High-Risk Prostate Cancers Are the Same

Men with 1 high-risk factor experience better outcomes following treatment than those with 2 or 3 high-risk factors, study finds.

Blacks Less Likely to Undergo Definitive Prostate Cancer Therapy

Blacks Less Likely to Undergo Definitive Prostate Cancer Therapy

Study of men with intermediate- or high-risk prostate cancer finds facility-level racial disparity in use of definitive treatment.

Timing of PSA Nadir Post-RP Predicts Biochemical Recurrence Risk

Timing of PSA Nadir Post-RP Predicts Biochemical Recurrence Risk

A detectable PSA nadir combined with shorter time to nadir after prostate cancer surgery is associated with a higher risk of biochemical recurrence.

Positive Lymph Node Prostate Cancer Care Patterns Characterized

Positive Lymph Node Prostate Cancer Care Patterns Characterized

63% of patients were managed initially with observation.

Active Surveillance for Intermediate-Risk PCa May Be Unsafe

Active Surveillance for Intermediate-Risk PCa May Be Unsafe

Nearly 1 in 3 patients diagnosed with Gleason 3+4 favorable intermediate-risk prostate cancer had their disease upgraded or upstaged at radical prostatectomy.

Top Complaint After Prostate Biopsy Is Infection

Top Complaint After Prostate Biopsy Is Infection

Most common infection in prostate biopsy was E. coli, followed by mild bleeding.

Vascular Targeted Photodynamic Tx Tied to Good Outcomes in Low-Risk PCa

Vascular Targeted Photodynamic Tx Tied to Good Outcomes in Low-Risk PCa

Throughout the study, a total of 115 lobes were treated and 82% achieved absent clinically significant cancer.

Vasectomy Poses Minimal Risk of Prostate Cancer

Vasectomy Poses Minimal Risk of Prostate Cancer

Researchers calculated that the absolute increase in lifetime risk of prostate cancer associated with vasectomy was just 0.6%.

Active Surveillance for Intermediate-risk Prostate Cancer Challenged

Active Surveillance for Intermediate-risk Prostate Cancer Challenged

Study reveals that a quarter of men with low-volume intermediate-risk prostate cancer had adverse pathologic features found at radical prostatectomy.

Tall, Obese Men More Likely to Have Aggressive Prostate Cancer

Tall, Obese Men More Likely to Have Aggressive Prostate Cancer

Every additional 4 inches of height was associated with a 21% increase in risk of being diagnosed with high-grade prostate cancer, and a 17% increased risk of dying from prostate cancer.

RP for Prostate Cancer May Not Offer Survival Advantage

RP for Prostate Cancer May Not Offer Survival Advantage

Randomized trial found no significant difference in all-cause and cancer-specific survival between radical prostatectomy and observation for localized prostate cancer.

Decisional Regret Doesn't Vary by Tx in PCa

Decisional Regret Doesn't Vary by Tx in PCa

Across time, only African-American race correlated with greater regret.

Germline Mutations Up in PCa Patients With Another Primary Cancer

Germline Mutations Up in PCa Patients With Another Primary Cancer

Men with prostate cancer and at least one additional primary cancer are enriched for harboring a germline deleterious mutation in a cancer-predisposing gene.

Radical Prostatectomy Use for High-Risk Prostate Cancer Rises Sharply

Radical Prostatectomy Use for High-Risk Prostate Cancer Rises Sharply

Over a 10-year period, radical prostatectomy use increased steadily while radiotherapy use declined

Prostate Atrophy, Inflammation Associated With Lower PCa Risk

Prostate Atrophy, Inflammation Associated With Lower PCa Risk

Both findings on biopsy also predict a lower odds of high-grade cancer.

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