Prostate Cancer Death Risk Higher in Diabetics

Share this article:
Two Distinct High-Risk Diabetes Populations ID'd in Children
Type 2 diabetes is associated with an increased risk of prostate cancer-specific mortality.

Men with type 2 diabetes are at increased risk for death from prostate cancer (PCa) or from any cause, Canadian researchers reported online ahead of print in Cancer Causes & Control.

A team led by Laurent Azoulay, MD, of McGill University in Montreal, studied 11,920 men newly diagnosed with non-metastatic PCa. The cohort included 1,132 men (9.5%) with pre-existing type 2 diabetes. A total of 3,605 deaths, including 1,792 from PCa, occurred during a mean 4.7 years of follow-up. Compared with non-diabetics, men with type 2 diabetes had a 23% increased risk of PCa mortality and 25% increased risk of all-cause mortality, after adjusting for potential confounders, including smoking, excessive alcohol use, comorbidities, and PCa-related variables.

The findings “may signal an association between hyperinsulinemia or other diabetes-associated metabolic derangements and cancer aggressivity,” the authors concluded.

Share this article:
You must be a registered member of RUN to post a comment.
close

Next Article in Prostate Cancer

More in Prostate Cancer

Blacks with Recurrent Prostate Cancer More Likely To Regret Treatment

Blacks with Recurrent Prostate Cancer More Likely To ...

Racial differences in prostate cancer (PCa) treatment regret more pronounced among those without sexual problems.

Androgen Deprivation Therapy (ADT) Raises Heart-Related Death Risk

Androgen Deprivation Therapy (ADT) Raises Heart-Related Death Risk

But overall risk of heart-related death risk from prostate cancer treatment is small, researchers say.

Men with More Female Partners Have Lower Prostate Cancer (PCa) Risk

Men with More Female Partners Have Lower Prostate ...

Men who have slept with more than 20 female partners are less likely to develop aggressive prostate cancer (PCa).