Prostate Cancer Death Risk Higher in Diabetics

Share this article:
Two Distinct High-Risk Diabetes Populations ID'd in Children
Type 2 diabetes is associated with an increased risk of prostate cancer-specific mortality.

Men with type 2 diabetes are at increased risk for death from prostate cancer (PCa) or from any cause, Canadian researchers reported online ahead of print in Cancer Causes & Control.

A team led by Laurent Azoulay, MD, of McGill University in Montreal, studied 11,920 men newly diagnosed with non-metastatic PCa. The cohort included 1,132 men (9.5%) with pre-existing type 2 diabetes. A total of 3,605 deaths, including 1,792 from PCa, occurred during a mean 4.7 years of follow-up. Compared with non-diabetics, men with type 2 diabetes had a 23% increased risk of PCa mortality and 25% increased risk of all-cause mortality, after adjusting for potential confounders, including smoking, excessive alcohol use, comorbidities, and PCa-related variables.

The findings “may signal an association between hyperinsulinemia or other diabetes-associated metabolic derangements and cancer aggressivity,” the authors concluded.

Share this article:
You must be a registered member of RUN to post a comment.
close

Next Article in Prostate Cancer

More in Prostate Cancer

High Cholesterol Linked with Prostate Cancer Recurrence

High Cholesterol Linked with Prostate Cancer Recurrence

Findings suggest that normalization of blood fats may reduce risk of prostate cancer.

Prostate Cancer Death Risk Higher After External Beam Radiation Therapy (EBRT) than Surgery

Prostate Cancer Death Risk Higher After External Beam ...

Mortality was greater with external beam radiotherapy across treatment-specific nomograms for predicting biochemical recurrence.

In Black Prostate Cancer Patients, Active Surveillance Safe

In Black Prostate Cancer Patients, Active Surveillance Safe

Researchers confident in this approach because candidates for active surveillance are a heavily screened population.