Overactive Bladder

Methylene Blue Improves Onabotulinum Toxin A Injection Technique

Methylene Blue Improves Onabotulinum Toxin A Injection Technique

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Methylene blue aids observation of the procedure and assessment of drug distribution.

Antimuscarinic Therapy for OAB Linked to Depression in Women

Antimuscarinic Therapy for OAB Linked to Depression in Women

Clinicians should be alert to the relationship between antimuscarinics usage and depressive disorder in OAB women and provide appropriate instructions for these patients.

Botulinum Toxin Evaluated for Overactive Bladder

Botulinum Toxin Evaluated for Overactive Bladder

Onabotulinumtoxin A successfully reduced urinary frequency and urgency, but not urgency urinary incontinence episodes.

Oxybutynin Overprescribed for Overactive Bladder in Elderly

Oxybutynin Overprescribed for Overactive Bladder in Elderly

Pharmacologic properties of oxybutynin may cause significant cognitive side effects in elderly persons.

OAB Drug Mirabegron Shows Superior Patient Adherence

OAB Drug Mirabegron Shows Superior Patient Adherence

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Treatment discontinuation rate is lower than that of traditional antimuscarinics, study finds.

Long-Term BoNT-A Therapy Compliance Low Among Men

Long-Term BoNT-A Therapy Compliance Low Among Men

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Only a quarter of men receiving injections of BoNT-A comply with the treatment long-term.

OAB Sacral Neuromodulation Causes Few Serious Adverse Events

OAB Sacral Neuromodulation Causes Few Serious Adverse Events

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Prospective study reveals a 1-year surgical intervention rate of 13%.

OnabotulinumtoxinA Provides Lasting Benefit in Overactive Bladder

OnabotulinumtoxinA Provides Lasting Benefit in Overactive Bladder

Consistent mean reductions in urinary incontinence; durable improvements in quality of life.

Surgical Revision Rate 4% for Mesh-Based Prolapse Surgery

Surgical Revision Rate 4% for Mesh-Based Prolapse Surgery

Reoperation rate for transvaginal mesh prolapse surgery is 4%.

Post-RP Radiation Therapy May Raise OAB Risk

Post-RP Radiation Therapy May Raise OAB Risk

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De novo OAB — defined as urgency with or without frequency and nocturia — developed in some patients.

Patients on Psychiatric Meds Report More Severe OAB Symptoms

Patients on Psychiatric Meds Report More Severe OAB Symptoms

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These same patients, however, had less intense detrusor overactivity, urodynamic evaluation revealed.

Specialists More Likely to Prescribe Newer OAB Drugs Initially

Specialists More Likely to Prescribe Newer OAB Drugs Initially

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Urologists and gynecologists are 49% and 30% more likely than primary care doctors to prescribe second-generation agents.

Potential Medication Misuse Common With OAB

Potential Medication Misuse Common With OAB

Potentially inappropriate medication use is prevalent in older adults undergoing antimuscarinic treatment for overactive bladder.

Mirabegron Found to Relieve Refractory OAB in Children

Mirabegron Found to Relieve Refractory OAB in Children

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Patients' median bladder capacity improved from 150 to 200 mL and continence improved in nearly 90% of patients.

Overactive Bladder Risk Higher in Women Who Smoke

Overactive Bladder Risk Higher in Women Who Smoke

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Researchers also find a significant association between smoking and secondary nocturnal enuresis.

Botox Effectively Treats New OAB After Incontinence Surgery

Botox Effectively Treats New OAB After Incontinence Surgery

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A high cure rate was observed in women with de novo OAB symptoms following transobturator tape surgery.

Combo Superior for Overactive Bladder in BPH Patients

Combo Superior for Overactive Bladder in BPH Patients

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Symptom improvement was greater in patients receiving tamsulosin plus darifenacin compared with tamsulosin monotherapy.

Pelvic Floor Stimulation Improves OAB in Perimenopausal Women

Pelvic Floor Stimulation Improves OAB in Perimenopausal Women

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Adding vaginal estrogen may sustain the effects.

Two-Drug Combo Effective for Severe OAB in Elderly

Two-Drug Combo Effective for Severe OAB in Elderly

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Among seniors with severe overactive bladder, a combination of solifenacin and mirabegron decreased incontinence by an average 3.5 episodes a day.

Sacral Neuromodulation Testing Increasing

Sacral Neuromodulation Testing Increasing

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The number of neuromodulation test procedures performed per physician has increased.

Overactive Bladder Medications Only Slightly Beneficial

Overactive Bladder Medications Only Slightly Beneficial

Small reductions in urge incontinence episodes, voids per day with daily dose of medications.

OAB Drugs Prescribed Less Frequently to Men

OAB Drugs Prescribed Less Frequently to Men

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A study found that 33.8% of women received anticholinergics compared with 19.4% of men.

Overactive Bladder Increases Falling Risk in the Elderly

Overactive Bladder Increases Falling Risk in the Elderly

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OAB treatment is associated with a decreased risk of falls, study finds.

Shared Decision Making in Managing Idiopathic and Neurogenic OAB

Communicating effectively about appropriate options and eliciting patient input for overactive bladder (OAB) can improve outcomes.

OAB, SUI Worse After Vaginal Birth

OAB, SUI Worse After Vaginal Birth

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Regardless of delivery type, obesity ups the risk of more severe urinary symptoms, study shows.

Overactive Bladder Found to Raise Nocturia Risk

Overactive Bladder Found to Raise Nocturia Risk

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In a study, severe nocturia predicted increased mortality risk.

Combined High-Dosage Drugs Shown to Ease Resistant OAB

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Elderly patients with OAB may benefit from combined high-dosage antimuscarinics.

Repeat BTXA Injections Okay for Non-Neurogenic OAB

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Repeat injections of onabotulinumtoxinA (BTXA) appear to benefit patients with non-neurogenic overactive bladder.

Stubborn Overactive Bladder Responds to Sacral Neuromodulation

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Improvements in efficacy and quality of life last at least six months, study finds.

OAB: Current and Emerging Therapies for Optimal Individualized Treatment

Keeping abreast of the most current treatments for idiopathic OAB can lead to improved outcomes and quality of life.

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