Overactive Bladder (OAB) - Renal and Urology News

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Overactive Bladder

Transdermal Gel for Overactive Bladder Launched

Stephan Cho April 27, 2012

Watson Pharmaceuticals of Parsippany, N.J., and Antares Pharma. Inc. of Ewing, NJ, have announced the launch of Gelnique (oxybutynin), a transdermal gel for the treatment of overactive bladder (OAB) with symptoms of urge urinary incontinence, urgency and frequency.

Novel Drug for Overactive Bladder Works Even If Antimuscarinics Do Not

Jody A. Charnow February 29, 2012

PARIS—Mirabegron, an experimental drug for overactive bladder (OAB), can effectively treat the condition in patients whether or not they failed previous antimuscarinic therapy, according to findings presented at the 27th Annual Congress of the European Association of Urology.

Repeated Toxin Injections Safe and Effective for Refractory Overactive Bladder

Jody A. Charnow December 26, 2011

Repeated injections of botulinum toxin type A (BoNTA) are safe and effective for the medium-term management of refractory overactive bladder (OAB) and idiopathic detrusor overactivity (IDO), according to British investigators.

Overactive Bladder Linked to Metabolic Syndrome in Women

Jody A. Charnow November 01, 2011

Metabolic syndrome is associated with overactive bladder (OAB) in women, according to researchers.

Botulinum Toxin Effective in OAB Patients without Detrusor Overactivity

Jody A. Charnow August 31, 2011

GLASGOW—Intravesical botulinum toxin may be an effective treatment for overactive bladder (OAB) without detrusor overactivity (DOA) on urodynamic assessment, researchers reported at the International Continence Society annual meeting.

Approval Sought for New Overactive Bladder Drug

Jody A. Charnow August 29, 2011

If cleared by the FDA, mirabegron would be the first oral treatment with a new mechanism of action for OAB in almost 30 years.

Antibiotics May Improve Treatment of Overactive Bladder

Jody A. Charnow August 29, 2011

GLASGOW—Antibiotics may be a useful adjunctive treatment for overactive bladder (OAB), according to British researchers.

Trigonal Injections of Botulinum Toxin Improve OAB Outcomes

Jody A. Charnow May 18, 2011

WASHINGTON, D.C.—Trigonal intradetrusor injections of botulinum toxin-A (BTX-A) results in greater reduction in overactive bladder (OAB) symptoms compared with trigone-sparing BTX-A injections, Irish investigators reported at the American Urological Association 2011 annual meeting.

Overactive Bladder Often Associated with Pelvic Organ Prolapse

John Schieszer May 18, 2011

WASHINGTON, D.C.—Posterior compartment pelvic organ prolapse (POP) in women is often associated with overactive bladder (OAB), and POP surgery may help to decrease OAB symptoms as well as detrusor overactive (DO), according to study findings presented at the American Urological Association 2011 annual meeting.

Surrogate Markers May Identify Age-Associated Biochemical Changes in OAB patients

John Schieszer May 18, 2011

WASHINGTON, D.C.—Urinary nerve growth factor (NGF) and MCP-1 may be surrogate markers for monitoring age-associated biochemical changes in patients with overactive bladder (OAB), according to data presented at the American Urological Association 2011 annual meeting.

'OAB-Dry' May Need to be Reassessed

John Schieszer May 17, 2011

WASHINGTON, D.C.—Questionnaires used to diagnose patients with overactive bladder (OAB) may identify anyone with polyuria, bladder hypersensitivity, and even OAB-wet with rare leakage episodes as OAB-dry, investigators reported at the American Urological Association 2011 annual meeting.

Overactive Bladder Found in One Fifth of Type 2 Diabetics

John Schieszer May 17, 2011

WASHINGTON, D.C—Japanese researchers found that more than one fifth of patients with type 2 diabetes receiving care at a dedicated diabetes center have overactive bladder (OAB).

Nocturia Is the Most Bothersome OAB Symptom in POTS Patients

John Schieszer May 17, 2011

WASHINGTON, D.C.—Nocturia is the most common overactive bladder (OAB) symptom affecting health-related quality of life (HRQL) in patients with postural tachycardia syndrome (POTS), investigators reported at the American Urological Association 2011 annual meeting.

Parkinson's Severity Associated with OAB Symptoms

John Schieszer May 17, 2011

WASHINGTON, D.C.—Overactive bladder (OAB) symptoms are common in patients with Parkinson's disease regardless of age and gender, and the severity of Parkinson's symptoms correlates with OAB symptoms, according to a study presented at the American Urological Association 2011 annual meeting.

OAB Symptoms Linked to Elevated Serum Leptin

John Schieszer May 16, 2011

WASHINGTON, D.C.—Elevation of serum leptin and a decrease in monocyte chemotactic protein-1 (MCP-1) levels are associated with overactive bladder (OAB) symptoms, according to new data presented at the American Urological Association 2011 annual meeting.

Sacral Neuromodulation Found Effective and Well-Tolerated

John Schieszer May 16, 2011

WASHINGTON, D.C.—Sacral neuromodulation with InterStim Therapy is safe and well tolerated as a treatment for patients with overactive bladder and those with urinary retention, French investigators reported at the American Urological Association 2011 annual meeting.

Adverse Events Common After Botulinum Toxin Injections

John Schieszer May 16, 2011

WASHINGTON, D.C.—Adverse events (AEs) after intravesical botulinum toxin type A for idiopathic detrusor overactivity (IDO) are encountered frequently, according to a new study presented at the American Urological Association 2011 annual meeting.

Botulinum Toxin Effective Long Term for Severe OAB

John Schieszer May 16, 2011

WASHINGTON, D.C.—Detrusor botulinum toxin type A injections are a safe and effective treatment long-term for patients with severe overactive bladder (OAB), Swiss researchers reported at the American Urological Association 2011 annual meeting.

OAB Affects Work Productivity

John Schieszer May 15, 2011

WASHINGTON, D.C.—Men and women who suffer from overactive bladder (OAB) report significantly greater levels of work limitations compared with those without urinary symptoms, according to a new study presented at the American Urological Association 2011 annual meeting.

Remission of Urologic Symptoms Not Uncommon

John Schieszer May 15, 2011

WASHINGTON, D.C.—The natural history of lower urinary tract symptoms (LUTS) and overactive bladder (OAB) may involve as much remission as progression, according to a new longitudinal study presented at the American Urological Association 2011 annual meeting.

Painless Laser Therapy for Overactive Bladder (PLTOAB)

A Study to Investigate How Effective and Safe Solifenacin Liquid Suspension is in Treating Children/Adolescents Aged 5 to Less Than 18 Years With Symptoms of Overactive Bladder (OAB) Compared to a Non-active Drug (LION)

Study of Overactive Bladder in Women With Prolapse (SOAP)

Assessment and Diagnostic Strategies for Neurogenic Bladder: Part I

Value of Preop Urodynamics for SUI Questioned

Device Cleared for Female Urinary Incontinence

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