Weigh Pros and Cons of West Nile Screening
Testing may be justified at centers in areas with high virus activity
Several transplant centers in the
“False positives can lead to not using organs that otherwise would have been suitable,” Dr. Humar said. “Another factor that confounds this issue is what type of test to use in the setting of a deceased donor.”
Although blood products are universally screened for the virus, he noted, no guidelines call for universal screening of donated kidneys and other solid organs.
So far, two multiple-transplant recipients have acquired
It is unclear how cost effective it would be to embrace universal testing for
If a community has a great deal of West Nile virus activity in a given year and a transplant program is considering screening donors for the virus, then it will need to consider issues that have not yet been thoroughly addressed, such as available assays, laboratory resources, turn-around time, and medicolegal concerns, Dr. Humar said.
The United Network for Organ Sharing only recommends testing of donated organs where there are significant prevalence rates.