Higher PSA Hikes Rescue Failure Risk
PSA levels and PSA doubling time (PSADT) prior to radiotherapy predict outcomes following rescue radiation therapy for men with prostate cancer.
Zvi Symon, MD, and his colleagues at
Overall the estimated three-year failure-free survival rate was 54%. A pre-radiotherapy PSA greater than 1 ng/mL and seminal vesicle involvement increased the risk of rescue failure 6.2 and 7.3 times, respectively, the investigators reported in the American Journal of Clinical Oncology (2006;29:446-450).