Flu Shots Safe And Effective For Transplant Patients
Influenza vaccination is safe and effective for renal transplant patients, according to European researchers.
Investigators at University Hospital Gasthuisberg in
The researchers defined seroprotection (SP) and seroreponse (SR) as a titer of 40 and higher and a fourfold rise in hemagglutination-inhibiting (HI) antibody titer, respectively. The two groups had similar SR rates, according to a report in the American Journal of Transplantation (2008;8:332-337). Post-vaccination SP rates among the transplant recipients were 92.7%, 78.7%, and 82.9% for A/H1N1, A/HcN2, and B, respectively.
Patients receiving mycophenolate mofetil had a 2.6 to five times lower SR, but they showed good post-vaccination SP rates. A boost dose did not increase SP or SR rates. The vaccinations did not affect allograft function nor did they cause rejection.
A recent study conducted at