News in Brief

Intestinal Autoimmunity Possibly Linked to ADT

Intestinal Autoimmunity Possibly Linked to ADT

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ADT for prostate cancer may be associated with a reduced risk of inflammatory bowel disease.

Shockwave Therapy May Ease Peyronie's Disease

Shockwave Therapy May Ease Peyronie's Disease

ESWT is associated with significantly increased odds of reduced plaques and pain relief.

Venous Thromboembolism Linked to High Uric Acid

Venous Thromboembolism Linked to High Uric Acid

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Highest vs lowest uric acid levels associated with a 2-fold increased risk of VTE.

Hip Fracture Rate Higher in Non-Dialysis CKD

Hip Fracture Rate Higher in Non-Dialysis CKD

Patients with non-dialysis chronic kidney disease (CKD) may be at elevated risk for hip fracture, according the Journal of Bone and Mineral Research.

New Study Supports Use of Trimodal Therapy for MIBC

New Study Supports Use of Trimodal Therapy for MIBC

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Researchers find no difference in 5-year disease-specific survival between multi-disciplinary bladder-sparing approach and radical cystectomy.

New Drug Cleared to Treat SHPT in Chronic Kidney Disease Patients

New Drug Cleared to Treat SHPT in Chronic Kidney Disease Patients

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Calcifediol formulation is indicated for CKD stage 3 or 4 patients with secondary hyperparathyroidism associated with vitamin D insufficiency.

Lupus Nephritis ESRD Has Worse Outcomes

Lupus Nephritis ESRD Has Worse Outcomes

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Researchers find an increased risk of death among patients.

Post-RP Radiation Therapy May Raise OAB Risk

Post-RP Radiation Therapy May Raise OAB Risk

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De novo OAB — defined as urgency with or without frequency and nocturia — developed in some patients.

Morbid Obesity Ups Viral Infection Risk After a Kidney Transplant

Morbid Obesity Ups Viral Infection Risk After a Kidney Transplant

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In a study, viral infections occurred in 52.4% of patients with a BMI of 35 kg/m2 or higher compared with 37.1% of those with a lower BMI.

Drug Cleared for Refractory Advanced Bladder Cancer

Drug Cleared for Refractory Advanced Bladder Cancer

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Atezolizumab received accelerated FDA approval for patients whose disease has progressed despite platinum-based chemotherapy.

Surgeons Perform First Penile Transplant in the US

Surgeons Perform First Penile Transplant in the US

The 15-hour surgery took place in early May.

N-Acetylcysteine May Protect Against CIN

N-Acetylcysteine May Protect Against CIN

N-acetylcysteine patients had significantly decreased odds of contrast-induced nephropathy.

Aminosalicylates Cut PCa Risk in Men with IBD

Aminosalicylates Cut PCa Risk in Men with IBD

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Researchers found an adjusted 68% decreased risk of prostate cancer in men with IBD who used aminosalicylate.

PSA Screening More Likely Among Blacks

PSA Screening More Likely Among Blacks

The odds of PSA screening were higher among blacks than non-Hispanic whites.

Fluoroquinolones May Be Unwarranted for High PSA

Fluoroquinolones May Be Unwarranted for High PSA

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PSA level declined by an average of 0.68 ng/mL in the treatment group.

Hidden Hypercalcemia Common in Hemodialysis Patients

Hidden Hypercalcemia Common in Hemodialysis Patients

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The condition is associated with a death risk similar to that of apparent hypercalcemia.

PTH Level Unrelated to Parathyroid Glands' Weight, Blood Flow

PTH Level Unrelated to Parathyroid Glands' Weight, Blood Flow

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Iranian study of hemodialysis patients with secondary hyperparathyroidism finds no significant correlation.

Silodosin Safe, Effective for Symptomatic BPH

Silodosin Safe, Effective for Symptomatic BPH

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Three quarters of patients experienced significant improvements in lower urinary tract symptoms and quality of life observed and were satisfied with treatment.

Mirabegron Found to Relieve Refractory OAB in Children

Mirabegron Found to Relieve Refractory OAB in Children

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Patients' median bladder capacity improved from 150 to 200 mL and continence improved in nearly 90% of patients.

Nighttime BP Elevated in Prediabetes Patients With CKD

Nighttime BP Elevated in Prediabetes Patients With CKD

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In these patients, systolic blood pressure at night was elevated by an average of 2.9 mm Hg.

Poor Appetite, Lower GFR Linked in Children With CKD

Poor Appetite, Lower GFR Linked in Children With CKD

Children with a ieGFR below 30 mL/min/1.73m2 have 4.5-fold greater odds of having a worse appetite.

Intradialytic Hypotension Hikes Long-Term Death Risk

Intradialytic Hypotension Hikes Long-Term Death Risk

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The condition is independently associated with a 60% increased risk of 5-year mortality in maintenance hemodialysis patients.

Racial Disparity in Survival Found in Pediatric Dialysis Patients

Racial Disparity in Survival Found in Pediatric Dialysis Patients

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African-American children are 64% more likely to die than white children.

Bariatric Surgery Type Influences Stone Risk

Bariatric Surgery Type Influences Stone Risk

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Roux-en-Y gastric bypass surgery is associated with a 73% increased pooled RR of kidney stones.

Suprapubic Tubes May Be Better for RALP Patients

Suprapubic Tubes May Be Better for RALP Patients

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Advantages in terms of bother and pain surface in a prospective randomized trial comparing suprapubic tubes and urethral catheters.

Rosiglitazone May Up Bladder Cancer Risk

Rosiglitazone May Up Bladder Cancer Risk

Exclusive rosiglitazone use is associated with 3-fold increased odds of bladder cancer.

Mid-Urethral Slings for SUI Offer Long-Term Efficacy

Mid-Urethral Slings for SUI Offer Long-Term Efficacy

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More than 95% of women reported no stress urinary incontinence at 2-, 5-, and 10 year follow-up.

Papillary RCC More Common in African Americans

Papillary RCC More Common in African Americans

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Racial difference found among patients undergoing robotic partial nephrectomy for renal tumors.

PAE Effect on Prostate Zones Characterized

PAE Effect on Prostate Zones Characterized

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Prostatic arterial embolization significantly reduced volumes of median lobes, central zones, peripheral zones, and whole prostate glands.

Hypospadias Prevalence Found to Vary Widely

Hypospadias Prevalence Found to Vary Widely

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True prevalence of hypospadias and related trends are difficult to estimate.

Statin Use May Raise Kidney Disease Risk

Statin Use May Raise Kidney Disease Risk

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Statin users had 30% increased odds of acute kidney injury and 36% increased odds of chronic kidney disease compared with non-users.

Study Supports Use of SWL for Moderate-Sized Stones

Study Supports Use of SWL for Moderate-Sized Stones

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SWL treatment success rate was 70.4% and 53.1% for stones less than 15 mm and 15 mm or larger, respectively.

Hyperkalemia Linked to Aldosterone Antagonist Use

Hyperkalemia Linked to Aldosterone Antagonist Use

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Researchers identified the association in a cohort of older patients with reduced ejection fraction after acute myocardial infarction.

RCC Surgery Outcomes Not Worse in Extremely Obese Patients

RCC Surgery Outcomes Not Worse in Extremely Obese Patients

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Study reveals no significant differences in hospital readmission rates and overall, cancer-specific, and recurrence-free survival rates.

Hyperkalemia-Diabetes Link Found in CKD Patients

Hyperkalemia-Diabetes Link Found in CKD Patients

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Among patients with stage 3 chronic kidney disease, hyperkalemia prevalence is significantly higher among diabetic than non-diabetics.

Low Chloride Levels Linked to Adverse Outcomes in Pre-dialysis CKD

Low Chloride Levels Linked to Adverse Outcomes in Pre-dialysis CKD

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Researchers observe an increased risk of a composite outcome of death from any cause and cardiovascular events.

Levocarnitine Improves Cardiac Function in Hemodialysis Patients

Levocarnitine Improves Cardiac Function in Hemodialysis Patients

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Patients also experienced a reduction in left ventricular mass index.

FDA Approves Hyperkalemia Drug

FDA Approves Hyperkalemia Drug

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Patiromer for oral suspension lowers potassium levels in hyperkalemic patients with chronic kidney disease.

Adding Beta-Lactams to Vancomycin Raises AKI Risk

Adding Beta-Lactams to Vancomycin Raises AKI Risk

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New studies may clarify the risks associated with antibiotic combinations that include vancomycin, a drug with well-known nephrotoxicities.

Waist-to-Height Ratio Best Predictor of Metabolic Syndrome

Waist-to-Height Ratio Best Predictor of Metabolic Syndrome

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Metabolic Syndrome was present in 74.5% of the cohort.

More Exercise Linked to Less Risk of Erectile Dysfunction

More Exercise Linked to Less Risk of Erectile Dysfunction

Analytic sample of 692 men wearing ActiGraph 7164 accelerometer confirms inverse association.

Alfuzosin Safe, Effective for Ureteral Stone Expulsion

Alfuzosin Safe, Effective for Ureteral Stone Expulsion

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Stone-free rate and expulsion time did not differ significantly between alfuzosin and tamsulosin.

Pre-Cystectomy CT Scans May Predict Outcomes

Pre-Cystectomy CT Scans May Predict Outcomes

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Computed tomography (CT) scans prior to radical cystectomy for invasive bladder cancer may be useful.

Prostate Cancer Death Risk Linked to Stress

Prostate Cancer Death Risk Linked to Stress

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Study finds a 66% increased risk of dying from the malignancy in prostate cancer patients with the highest stress levels.

Finasteride Use May Lower Bladder Cancer Risk in Men

Finasteride Use May Lower Bladder Cancer Risk in Men

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The malignancy is 36% less likely to develop, after adjusting for age and smoking, data show.

Early Chemotherapy Offers No Survival Edge in mCRPC

Early Chemotherapy Offers No Survival Edge in mCRPC

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Giving docetaxel before abiraterone does not improve progression-free and overall survival compared with the reverse sequence.

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