News in Brief

Serum Uromodulin May Predict CKD Development

Serum Uromodulin May Predict CKD Development

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Uromodulin may be a novel predictive serum biomarker.

Men With PCa Most Likely to Die From Other Causes

Men With PCa Most Likely to Die From Other Causes

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Non-metastatic prostate cancer patients are more likely to die from causes other than the disease.

Methylene Blue Improves Onabotulinum Toxin A Injection Technique

Methylene Blue Improves Onabotulinum Toxin A Injection Technique

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Methylene blue aids observation of the procedure and assessment of drug distribution.

Drug Approved for Complicated Urinary Tract Infections

Drug Approved for Complicated Urinary Tract Infections

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Vabomere, which combines meropenem and vaborbactam, demonstrated superior efficacy to piperacillin/tazobactam.

Low-Dose Aspirin May Lower Preeclampsia Risk

Low-Dose Aspirin May Lower Preeclampsia Risk

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Women at high risk for preeclampsia who took 150 mg of aspirin daily during pregnancy had 62% lower odds of developing the condition.

FDA Clears Betrixaban for VTE Prophylaxis

FDA Clears Betrixaban for VTE Prophylaxis

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Fewer VTE events were observed in the betrixaban than enoxaparin arm.

Positive Lymph Node Prostate Cancer Care Patterns Characterized

Positive Lymph Node Prostate Cancer Care Patterns Characterized

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63% of patients were managed initially with observation.

HD Catheters Linked With Highest Rate of Bloodstream Infections

HD Catheters Linked With Highest Rate of Bloodstream Infections

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Nearly 70% of access-related bloodstream infections occurred in hemodialysis patients with central venous catheters.

Low Tryptophan May Signal Diabetic Nephropathy

Low Tryptophan May Signal Diabetic Nephropathy

There was a significant association for Trp with the event of rapid decline in eGFR.

Outpatient IPP Surgery on the Rise

Outpatient IPP Surgery on the Rise

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The Southeast region performed the highest proportion of outpatient surgeries (46.7%), followed by the Midwest, Southwest, West, and Northeast.

'Real-World' Data Support PUL Use for LUTS

'Real-World' Data Support PUL Use for LUTS

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PUL involves placement of small permanent metallic implants into the prostate that lift the lateral lobes away from the urethra and remove obstruction.

Chronic Prostatitis Has Adverse Effects on Sperm

Chronic Prostatitis Has Adverse Effects on Sperm

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CBP was associated with a reduction in sperm concentration, sperm vitality, sperm total and progressive motility.

Coffee Consumption Does Not Worsen ADPKD

Coffee Consumption Does Not Worsen ADPKD

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Coffee drinkers did not have a statistically significant difference in kidney size or estimated glomerular filtration rate compared with those who did not drink coffee.

HIV-Infected Living Kidney Donors Have Low ESRD Risk

HIV-Infected Living Kidney Donors Have Low ESRD Risk

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HIV-positive individuals with well-controlled disease and no comorbidities have a low risk of ESRD following living kidney donation.

Abiraterone Plus ADT Ups Prostate Cancer Patient Survival

Abiraterone Plus ADT Ups Prostate Cancer Patient Survival

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The 3-year overall survival rate among prostate cancer patients starting long-term hormone therapy was 83% vs 76% for men receiving abiraterone plus ADT vs ADT alone.

Cinacalcet May Lower Death Risk in Dialysis Subgroups

Cinacalcet May Lower Death Risk in Dialysis Subgroups

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Researchers found lower all-cause mortality for cinacalcet-treated patients concomitantly treated with vitamin D and phosphate binders, for example.

Bladder Cancer Patient Smoking Intensity Influences Survival

Bladder Cancer Patient Smoking Intensity Influences Survival

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Patients smoking 1 or more packs of cigarettes per day had a higher risk of death compared with those who smoked less than 1.

Stenting May Improve Transplant Renal Artery Stenosis Outcomes

Stenting May Improve Transplant Renal Artery Stenosis Outcomes

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Angioplasty plus stenting is associated with less residual stenosis and a lower restenosis rate compared with angioplasty alone.

AKI Predictors in PE Patients Identified

AKI Predictors in PE Patients Identified

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Chronic kidney disease and anemia are associated with an increased risk for acute kidney injury in patients with pulmonary embolism.

Oral ED Drugs Found to Benefit Infertile Men

Oral ED Drugs Found to Benefit Infertile Men

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Oral PDE5 inhibitors improve sperm parameters and can treat erectile dysfunction in men.

OAB Drug Mirabegron Shows Superior Patient Adherence

OAB Drug Mirabegron Shows Superior Patient Adherence

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Treatment discontinuation rate is lower than that of traditional antimuscarinics, study finds.

Anemia Indication Sought for Phosphate Binder

Anemia Indication Sought for Phosphate Binder

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Company asks FDA to approve ferric citrate for iron deficiency anemia in patients with non-dialysis dependent chronic kidney disease.

Kidney Cancer Linked to Obesity

Kidney Cancer Linked to Obesity

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Study also finds associations between adiposity and 10 other cancers, particularly digestive and hormone-related malignancies.

Nivolumab Approved for Refractory Urothelial Carcinoma

Nivolumab Approved for Refractory Urothelial Carcinoma

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The drug is indicated for treating patients with locally advanced or metastatic disease that progresses despite platinum-containing chemotherapy.

Long-Term BoNT-A Therapy Compliance Low Among Men

Long-Term BoNT-A Therapy Compliance Low Among Men

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Only a quarter of men receiving injections of BoNT-A comply with the treatment long-term.

Use of 5-ARIs May Reduce Blood Loss During TURP

Use of 5-ARIs May Reduce Blood Loss During TURP

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The finasteride and dutasteride recipients had significantly less mean blood loss than the placebo group.

Benign Disease Found in 14% of PN Cases

Benign Disease Found in 14% of PN Cases

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The most common types of benign pathology were oncocytoma, angiomyolipoma, and complex cysts.

Black Gout Sufferers Have Worse HRQoL

Black Gout Sufferers Have Worse HRQoL

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Blacks had significantly higher median baseline serum urate levels compared to whites.

Aortic Calcification in CKD Patients Linked to Nutrition

Aortic Calcification in CKD Patients Linked to Nutrition

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The median aortic calcification index (ACI) decreased significantly with increasing geriatric nutritional risk index tertile.

Post-Transplant Kidney Stones Characterized

Post-Transplant Kidney Stones Characterized

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Only 1% of patients develop kidney stones after kidney transplantation.

Urinary Cancer Risk Lower in Spironolactone Users

Urinary Cancer Risk Lower in Spironolactone Users

Spironolactone use was associated with 12% decreased odds of prostate cancer in male patients and 19% decreased odds of bladder cancer in female patients.

Chronic Periodontitis Increases ED Risk

Chronic Periodontitis Increases ED Risk

Chronic periodontitis was associated with 2.2-fold increased odds of ED.

Higher Testosterone Levels May Hike Renal Stone Risk

Higher Testosterone Levels May Hike Renal Stone Risk

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Mean levels of total serum testosterone and serum dihydrotestosterone were significantly higher in urolithiasis cases compared with controls.

Study: Older Age Should Not Preclude Partial Nephrectomy

Study: Older Age Should Not Preclude Partial Nephrectomy

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Partial and radical nephrectomy were associated with similar cancer-specific and overall survival in elderly patients.

FDA Approves Removal of Boxed Warning for Hyperkalemia Drug

FDA Approves Removal of Boxed Warning for Hyperkalemia Drug

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Updated label for patiromer now recommends the drug be taken at least 3 hours before or after other oral medications.

SHPT Surgical Procedures Equally Effective

SHPT Surgical Procedures Equally Effective

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Randomized study compared total parathyroidectomy with and without autotransplantation.

Prostate Cancer BCR Risk Not Linked to Statin Use

Prostate Cancer BCR Risk Not Linked to Statin Use

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Over a median follow-up of 70 months, 15% of men studied experienced biochemical recurrence.

Bacteremia in UTI Patients Tied to Abnormal CT Findings

Bacteremia in UTI Patients Tied to Abnormal CT Findings

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In a study of 189 adult UTI patients who underwent CT scans, investigators identified bacteremia in 40.2%.

Hypertension May Raise Prostate Cancer Risk

Hypertension May Raise Prostate Cancer Risk

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Data from 21 observational studies showed an 8% increased risk of prostate cancer.

Post-ESWL Renal Hematoma Linked to High, Low BMI

Post-ESWL Renal Hematoma Linked to High, Low BMI

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High and low body mass index are can cause renal hematoma for patients undergoing extracorporeal shock wave lithotripsy.

Low Sodium Levels Up  PD Patient Mortality

Low Sodium Levels Up PD Patient Mortality

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Patients in the lowest serum sodium group had a 49% increased risk of dying compared with those who had the highest serum sodium levels.

Vitamin D Supplements Do Not Raise Stone Risk

Vitamin D Supplements Do Not Raise Stone Risk

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Vitamin D supplementation increased the risk of hypercalcemia and hypercalciuria but did not increase the risk of kidney stones.

Low Hemoglobin Associated With Elevated Risk of CIN

Low Hemoglobin Associated With Elevated Risk of CIN

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CIN developed in 14.7% of patients with low hemoglobin levels compared with 5% of those with normal levels.

Tight Glycemic Control May Help Diabetic NMIBC Patients

Tight Glycemic Control May Help Diabetic NMIBC Patients

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Patients with diabetes had a significant 42% increased risk of recurrence of cancer and 79% increased risk of progression.

Reduced Kidney Function Ups Likelihood of AFib

Reduced Kidney Function Ups Likelihood of AFib

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Over a median follow-up of 3.7 years, researchers observed 159 incident cases of atrial fibrillation.

SHPT Risk Factors Identified

SHPT Risk Factors Identified

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Serum phosphorus and serum creatinine found to be independent predictors of secondary hyperparathyroidism.

Intestinal Autoimmunity Possibly Linked to ADT

Intestinal Autoimmunity Possibly Linked to ADT

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ADT for prostate cancer may be associated with a reduced risk of inflammatory bowel disease.

Shockwave Therapy May Ease Peyronie's Disease

Shockwave Therapy May Ease Peyronie's Disease

ESWT is associated with significantly increased odds of reduced plaques and pain relief.

Venous Thromboembolism Linked to High Uric Acid

Venous Thromboembolism Linked to High Uric Acid

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Highest vs lowest uric acid levels associated with a 2-fold increased risk of VTE.

Hip Fracture Rate Higher in Non-Dialysis CKD

Hip Fracture Rate Higher in Non-Dialysis CKD

Patients with non-dialysis chronic kidney disease (CKD) may be at elevated risk for hip fracture, according the Journal of Bone and Mineral Research.

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