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New Assay Predicts PCa Recurrence After Surgery

Jody A. Charnow May 23, 2012

A recently approved diagnostic assay may improve clinicians' ability to predict a prostate cancer patient's risk of clinical recurrence after radical prostatectomy (RP), a company announced at the American Urological Association 2012 annual meeting.

New Drug Prolongs Survival in Men with Late-Stage PCa

Jody A. Charnow May 23, 2012

Enzalutamide, an investigational medication formerly known as MDV3100, prolongs survival by nearly five months in men with late-stage prostate cancer previously treated with docetaxel, according to data presented at the American Urological Association 2012 annual meeting.

Healthy Diet May Protect Against LUTS

Jody A. Charnow May 23, 2012

Healthy eating may lower the risk of lower urinary tract symptoms (LUTS), according to data presented at the American Urological Association 2012 annual meeting.

Fesoterodine Relieves Nocturnal Urgency in OAB Patients

Jody A. Charnow May 23, 2012

Flexible-dose fesoterodine is superior to placebo in decreasing the number of nocturnal urgency episodes and nocturnal micturitions in patients with overactive bladder (OAB), researchers reported at the American Urological Association 2012 annual meeting.

OAB Patients Most Bothered by Urgency

Stephan Cho May 23, 2012

Patients with overactive bladder (OAB) say they are most bothered by symptoms of urinary urgency either as a primary complaint or as a driving symptom for frequency, according to a pilot study presented at the American Urological Association 2012 annual meeting.

BoNTA Safe, Effective for Diabetic OAB Patients

Stephan Cho May 23, 2012

Diabetes has no influence on intravesical botulinum toxin type A (BoNTA) injection in overactive bladder (OAB) patients, researchers reported at the American Urological Association 2012 annual meeting.

Intermittent ADT May Offer Survival Edge in Advanced Prostate Cancer

Jody A. Charnow May 22, 2012

Intermittent androgen deprivation (IAD) therapy is associated with improved all-cause and prostate cancer (PCa)-specific mortality among elderly patients with advanced PCa, according to data presented at the American Urological Association 2012 annual meeting.

Novel Catheter May Prevent Patient Injuries

Jody A. Charnow May 22, 2012

Researchers have developed a novel catheter that they say can cut down on the number of catheter-related injuries, according to a presentation at the American Urological Association 2012 annual meeting.

Pyuria, Microhematuria Duration After Prostate Surgery Quantified

Jody A. Charnow May 22, 2012

Pyuria persists longer than microhematuria after prostatic surgery and it is significantly associated with resected prostate weight, according to a study presented at the American Urological Association 2012 annual meeting.

Durable Oncologic Outcomes Reported for RARP

Stephan Cho May 22, 2012

Robotic-assisted radical prostatectomy (RARP) is associated with long-term biochemical relapse-free survival, according to a study presented at the American Urological Association 2012 annual meeting.

Women More Likely to Die from Bladder Cancer

Stephan Cho May 22, 2012

Women are more likely than men to have advanced bladder cancer disease found at the time of radical cystectomy and to die from the cancer, according to researchers at the American Urological Association 2012 annual meeting.

UI Incidence Low After Image-Guided Radiation Therapy

Stephan Cho May 22, 2012

Prostate cancer (PCa) patients undergoing image-guided radiation therapy (IGRT) experience a low incidence of treatment-related urinary incontinence (UI), researchers reported at the American Urological Association 2012 annual meeting.

Prolonged Surgical Delay Increases Bladder Cancer Recurrence Risk

Stephan Cho May 22, 2012

A prolonged delay between bladder cancer diagnosis and cystectomy is associated with an increased risk of disease recurrence and mortality, according to a study presented at the American Urological Association 2012 annual meeting.

Renal, Urothelial Cancers Linked to Lower Kidney Function

Jody A. Charnow May 22, 2012

Lower renal function is associated with an increased independent risk for renal and urothelial cancer, according to data presented at the American Urological Association 2012 annual meeting.

Urologists Condemn Task Force's Anti-PSA Testing Stance

Jody A. Charnow May 22, 2012

The U.S. Preventive Services Task Force (USPSTF) on Monday released its final recommendations on PSA-based screening for prostate cancer (PCa), which advises against the practice and gives it a grade D rating, meaning the task force believes there is "moderate or high certainty that the service has no net benefit or that the harms outweigh the benefit."

Data Suggest Caution in the Use of Nonsurgical Management of Renal Tumors

Jody A. Charnow May 22, 2012

New findings suggest a need to proceed with caution when deciding whether to use nonsurgical management (NSM) for patients with renal cell carcinoma, according to a report presented at the American Urological Association 2012 annual meeting.

Finasteride Reduces PSA, Prostate Volume in BPH Patients

Jody A. Charnow May 21, 2012

One year of finasteride treatment can decrease PSA levels and prostate volume significantly in men with benign prostatic hyperplasia (BPH), and the magnitude of change may improve clinicians' ability to diagnose prostate cancer in patients with elevated PSA levels and a prior negative biopsy, researchers reported at the American Urological Association 2012 annual meeting.

Dutasteride May Decrease Risk of BPH Clinical Progression

Jody A. Charnow May 21, 2012

Men with enlarged prostates may be able to decrease the likelihood of clinical progression of their condition by taking dutasteride, according to study findings presented at the American Urological Association 2012 annual meeting.

Statins May Decrease Prostate Growth

Jody A. Charnow May 21, 2012

Statin therapy may slow prostate growth in men with an elevated PSA level and a negative prostate biopsy, according to findings presented at the American Urological Association 2012 annual meeting.

UTUC Tumor Location Affects Oncologic Outcomes

Jody A. Charnow May 21, 2012

Tumor location independently predicts cancer-specific survival (CSS) and recurrence-free survival (RFS) in patients with upper tract urothelial carcinoma (UTUC), researchers reported at the American Urological Association 2012 annual meeting.

Expert Q&A

Optimal Sequencing of the New Prostate Cancer Drugs: An Interview with E. David Crawford, MD

Several new drugs have become available for treating advanced prostate cancer in the past year and a half. Dr. Crawford talks to Renal & Urology News about the possible ways in which these drugs might be used.

Commentary

Prostate Cancer Screening: Moving Beyond PSA

The merits of PSA screening have been widely debated due largely to its low specificity for prostate cancer (PCa), especially for high-grade disease.

On The Forefront

Sickle Cell Trait and Medullary Renal Carcinoma

A 55-year-old Caucasian woman initially presented to one of Cleveland Clinic's regional outpatient urology clinics with gross hematuria and an obstructing right ureteral stone.

Legal Issues

After Radical Prostatectomy, Patient Learns He Never Had Prostate Cancer

Is honesty always the best policy? That is the question that a urologist had to grapple with in this case.

Renal Nutrition Update

High Protein Intake May Elevate Levels of Advanced Glycation End Products

Advanced glycation end products (AGEs) are byproducts of non-enzymatic chemical reactions between sugars and amino acids, lipids, or DNA. A wide range of molecules fall into this category.