New Warnings Required for Gadolinium-Based Contrast Agents

Share this article:

The FDA is requiring that gadolinium-based contrast agents (GBCAs) carry new warnings on their labels about the risk of nephrogenic systemic fibrosis (NSF) if administered to certain patients with kidney disease.

Three GBCAs—Magnevist, Omniscan, and Optimark—will be described as inappropriate for use among patients with acute kidney injury or chronic severe kidney disease, according to the FDA. All GBCA labels will emphasize the need to screen patients to detect these types of kidney problems prior to administration.

NSF is a condition involving the formation of excess fibrous connective tissue in the skin, joints, eyes, and internal organs. Symptoms can include scaling, hardening and tightening of the skin, red or dark patches on the skin, and stiffness. NSF can lead to death, particularly if it involves organs, the FDA said.

Share this article:
You must be a registered member of RUN to post a comment.
close

Next Article in Acute Kidney Injury

More in Acute Kidney Injury

Chronic Kidney Disease (CKD) Predicts Acute Kidney Injury (AKI) After Renal Cell Carcinoma Surgery

Chronic Kidney Disease (CKD) Predicts Acute Kidney Injury ...

Other predictors include neurovascular disease, obesity, and surgical approach.

FDA Clears Lab Test for Predicting Acute Kidney Injury (AKI)

FDA Clears Lab Test for Predicting Acute Kidney ...

NephroCheck detects substances in the urine that are associated with acute kidney injury (AKI).

Causes of Acute Interstitial Nephritis (AIN) Differ in the Elderly

Causes of Acute Interstitial Nephritis (AIN) Differ in ...

Individuals aged 65 and older are more likely than younger people to develop AIN as a result of medication use.